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Risk Factors for Methicillin-Resistant Staphylococcus aureus Surgical Site Infection

Published online by Cambridge University Press:  02 January 2015

Stephan Harbarth*
Affiliation:
Infection Control Program, University of Geneva Hospitals and Medical School, Geneva, Switzerland
Benedikt Huttner
Affiliation:
Infection Control Program, University of Geneva Hospitals and Medical School, Geneva, Switzerland
Pascal Gervaz
Affiliation:
Department of Surgery, University of Geneva Hospitals and Medical School, Geneva, Switzerland
Carolina Fankhauser
Affiliation:
Infection Control Program, University of Geneva Hospitals and Medical School, Geneva, Switzerland
Marie-Noelle Chraiti
Affiliation:
Infection Control Program, University of Geneva Hospitals and Medical School, Geneva, Switzerland
Jacques Schrenzel
Affiliation:
Microbiology Laboratory, University of Geneva Hospitals and Medical School, Geneva, Switzerland
Marc Licker
Affiliation:
Department of Anesthesiology, Pharmacology and Intensive Care, University of Geneva Hospitals and Medical School, Geneva, Switzerland
Didier Pittet
Affiliation:
Infection Control Program, University of Geneva Hospitals and Medical School, Geneva, Switzerland
*
Infection Control Program, University of Geneva Hospitals and Medical School, 24, rue Micheli-du-Crest, 1211 Geneva 14 - , Switzerland (stephan.harbarth@hcuge.ch)

Abstract

We prospectively evaluated 46 possible risk factors for methicillin-resistant Staphylococcus aureus (MRSA) surgical site infection (SSI) among patients with MRSA carriage in a large intervention study. Of 6,130 study patients, 68 (1.1%) developed MRSA SSI, which occurred a median of 14 days after surgery. Risk factors associated with MRSA SSI were receipt of emergency surgery, presence of comorbid condition, receipt of immunosuppressive therapy, receipt of contaminated surgery, and a surgical duration longer than the 75th percentile. MRSA carriage on admission did not predict MRSA SSI.

Type
Concise Communication
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2008

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References

1.Davis, KA, Stewart, JJ, Crouch, HK, Florez, CE, Hospenthal, D. Methicillin-resistant Staphylococcus aureus (MRSA) nares colonization at hospital admission and its effect on subsequent MRSA infection. Clin Infect Dis 2004;39:776782.CrossRefGoogle ScholarPubMed
2.Morange-Saussier, V, Giraudeau, B, van der Mee, N, Lermusiaux, P, Quentin, R. Nasal carriage of methicillin-resistant Staphylococcus aureus in vascular surgery. Ann Vase Surg 2006;20:767772.Google Scholar
3.Manian, FA, Meyer, PL, Setzer, J, Senkel, D. Surgical site infections associated with methicillin-resistant Staphylococcus aureus: do postoperative factors play a role? Clin Infect Dis 2003;36:863868.CrossRefGoogle ScholarPubMed
4.Harbarth, S, Fankhauser, C, Schrenzel, J, et al.Universal screening for methicillin-resistant Staphylococcus aureus at hospital admission and nosocomial infection in surgical patients. JAMA 2008;299:11491157.Google Scholar
5.Mangram, AJ, Horan, TC, Pearson, ML, Silver, LC, Jarvis, WR. Guideline for prevention of surgical site infection, 1999. Infect Control Hosp Epidemiol 1999;20:250278.CrossRefGoogle ScholarPubMed
6.Anderson, DJ, Sexton, DJ, Kanafani, ZA, Auten, G, Kaye, KS. Severe surgical site infection in community hospitals: epidemiology, key procedures, and the changing prevalence of methicillin-resistant Staphylococcus aureus. Infect Control Hosp Epidemiol 2007;28:10471053.CrossRefGoogle ScholarPubMed
7.Engemann, JJ, Carmeli, Y, Cosgrove, SE, et al.Adverse clinical and economic outcomes attributable to methicillin resistance among patients with Staphylococcus aureus surgical site infection. Clin Infect Dis 2003;36:592598.CrossRefGoogle ScholarPubMed
8.Marshall, C, Wolfe, R, Kossmann, T, Wesselingh, S, Harrington, G, Spelman, D. Risk factors for acquisition of methicillin-resistant Staphylococcus aureus (MRSA) by trauma patients in the intensive care unit. J Hosp Infect 2004;57:245252.CrossRefGoogle ScholarPubMed
9.Shams, WE, Rapp, RP. Methicillin-resistant staphylococcal infections: an important consideration for orthopedic surgeons. Orthopedics 2004;27:565568.CrossRefGoogle ScholarPubMed
10.San Juan, R, Chaves, F, Lopez Gude, MJ, et al.Staphylococcus aureus post-sternotomy mediastinitis: description of two distinct acquisition pathways with different potential preventive approaches. J Thorac Cardiovasc Surg 2007;134:670676.Google Scholar