Published in:
01-10-2015 | Reply
Response to: Relationship between preeclampsia, gestational hypertension, and vitamin D receptor (VDR) gene polymorphisms
Author:
Rimpi Singla
Published in:
Archives of Gynecology and Obstetrics
|
Issue 4/2015
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Excerpt
Pathophysiology of preeclampsia, and hence preventive measures are still not elucidated. One hypothesis states that it results from superficial placentation due to immune maladaptation [
1]. Vitamin D (1,25(OH)2D), through its immunomodulatory properties, has been shown to control these adverse immune reactions [
2,
3]. It has an important role in promoting a shift from Th1 to a Th2-dominated pattern in immune response which is favourable for pregnancy [
4,
5]. …