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Archives of Gynecology and Obstetrics
Published in: Archives of Gynecology and Obstetrics 4/2015

01-10-2015 | General Gynecology

Lactobacilli vaginal colonisation after oral consumption of Respecta® complex: a randomised controlled pilot study

Authors: Davide De Alberti, Rosario Russo, Fabio Terruzzi, Vincenzo Nobile, Arthur C. Ouwehand

Published in: Archives of Gynecology and Obstetrics | Issue 4/2015

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Abstract

Purpose

The aim of the current pilot study was to determine if oral consumption of a combination of two probiotics; L. acidophilus La-14, L. rhamnosus HN001, and bovine lactoferrin (Respecta® complex), would lead to the detection with molecular techniques of the consumed probiotic strains in the vagina.

Methods

Healthy volunteers (40) consumed the study product twice daily for 2 weeks. Vaginal swabs were collected at 0, 1, 2 and 3 weeks and analysed for the consumed organisms by qPCR.

Results

Vaginal L. rhamnosus and L. acidophilus levels were significantly increased on days 14 and 21. On days 14 and 21 a significant number of women had increased levels of vaginal L. acidophilus and on days 7 and 21 a significant number of women had increased levels of vaginal L. rhamnosus.

Conclusions

Consumption of L. acidophilus La-14, L. rhamnosus HN001 in combination with bovine lactoferrin leads to vaginal detection; even 1 week after consumption was stopped. This provides a basis for future studies on urogenital tract health.
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Metadata
Title
Lactobacilli vaginal colonisation after oral consumption of Respecta® complex: a randomised controlled pilot study
Authors
Davide De Alberti
Rosario Russo
Fabio Terruzzi
Vincenzo Nobile
Arthur C. Ouwehand
Publication date
01-10-2015
Publisher
Springer Berlin Heidelberg
Published in
Archives of Gynecology and Obstetrics / Issue 4/2015
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-015-3711-4

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