Issue 1/2012
Content (119 Articles)
Erratum to: Genome-wide analysis of the mouse lung transcriptome reveals novel molecular gene interaction networks and cell-specific expression signatures
Rudi Alberts, Lu Lu, Robert W Williams, Klaus Schughart
Inhibition of Pyk2 blocks lung inflammation and injury in a mouse model of acute lung injury
Yingli Duan, Jonathan Learoyd, Angelo Y Meliton, Alan R Leff, Xiangdong Zhu
The pathogenesis of COPD and IPF: Distinct horns of the same devil?
Marco Chilosi, Venerino Poletti, Andrea Rossi
Diminished levels of nasal S100A7 (psoriasin) in seasonal allergic rhinitis: an effect mediated by Th2 cytokines
Anne Månsson Kvarnhammar, Camilla Rydberg, Malin Järnkrants, Mia Eriksson, Rolf Uddman, Mikael Benson, Lars-Olaf Cardell
Systemic inflammatory profile and response to anti-tumor necrosis factor therapy in chronic obstructive pulmonary disease
Matthew J Loza, Rosemary Watt, Frédéric Baribaud, Elliot S Barnathan, Stephen I Rennard
Endothelial-monocyte activating polypeptide II disrupts alveolar epithelial type II to type I cell transdifferentiation
Yao Chen, Susan K Legan, Anne Mahan, Janet Thornton, Haiming Xu, Margaret A Schwarz
Surfactant Protein D modulates allergen particle uptake and inflammatory response in a human epithelial airway model
Carsten Schleh, Barbara M Rothen-Rutishauser, Fabian Blank, Hans D Lauenstein, Matthias Nassimi, Norbert Krug, Armin Braun, Veit J Erpenbeck, Peter Gehr, Jens M Hohlfeld
Inhibition of allergic airway responses by heparin derived oligosaccharides: identification of a tetrasaccharide sequence
Tahir Ahmed, Gregory Smith, Iontcho Vlahov, William M Abraham
Is low dose inhaled corticosteroid therapy as effective for inflammation and remodeling in asthma? A randomized, parallel group study
Melissa Baraket, Brian GG Oliver, Janette K Burgess, Sam Lim, Gregory G King, Judith L Black
"GOLD or lower limit of normal definition? a comparison with expert-based diagnosis of chronic obstructive pulmonary disease in a prospective cohort-study"
Gülmisal Güder, Susanne Brenner, Christiane E Angermann, Georg Ertl, Matthias Held, Alfred P Sachs, Jan-Willem Lammers, Pieter Zanen, Arno W Hoes, Stefan Störk, Frans H Rutten
Fractionated breath condensate sampling: H2O2 concentrations of the alveolar fraction may be related to asthma control in children
Jordis Trischler, Nick Merkel, Stephanie Könitzer, Christina-Maria Müller, Susanne Unverzagt, Christiane Lex
Observational study on the impact of initiating tiotropium alone versus tiotropium with fluticasone propionate/salmeterol combination therapy on outcomes and costs in chronic obstructive pulmonary disease
Arjun Chatterjee, Manan Shah, Anna O D'Souza, Benno Bechtel, Glenn Crater, Anand A Dalal
Gastrin-releasing peptide receptor expression in non-cancerous bronchial epithelia is associated with lung cancer: a case-control study
Ann Marie Egloff, Autumn Gaither Davis, Yongli Shuai, Stephanie Land, Joseph M Pilewski, James D Luketich, Rodney Landreneau, York E Miller, Jennifer R Grandis, Jill M Siegfried
Effects of hypercapnia and NO synthase inhibition in sustained hypoxic pulmonary vasoconstriction
Farzaneh Ketabchi, Hossein A Ghofrani, Ralph T Schermuly, Werner Seeger, Friedrich Grimminger, Bakytbek Egemnazarov, S Mostafa Shid-Moosavi, Gholam A Dehghani, Norbert Weissmann, Natascha Sommer
Association of IREB2 and CHRNA3polymorphisms with airflow obstruction in severe alpha-1 antitrypsin deficiency
Woo Jin Kim, Alice M Wood, Alan F Barker, Mark L Brantly, Edward J Campbell, Edward Eden, Gerard McElvaney, Stephen I Rennard, Robert A Sandhaus, James M Stocks, James K Stoller, Charlie Strange, Gerard Turino, Edwin K Silverman, Robert A Stockley, Dawn L DeMeo
Poractant alfa (Curosurf®) increases phagocytosis of apoptotic neutrophils by alveolar macrophages in vivo
Coen HMP Willems, Florian Urlichs, Silvia Seidenspinner, Steffen Kunzmann, Christian P Speer, Boris W Kramer
Differences of cardiac output measurements by open-circuit acetylene uptake in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension: a cohort study
Martin Schwaiblmair, Christian Faul, Wolfgang von Scheidt, Thomas M Berghaus
T lymphocyte insensitivity to corticosteroids in chronic obstructive pulmonary disease
Manminder Kaur, Lucy JC Smyth, Paul Cadden, Seamus Grundy, David Ray, Jonathan Plumb, Dave Singh
Relationship between body composition, inflammation and lung function in overweight and obese asthma
Hayley A Scott, Peter G Gibson, Manohar L Garg, Jeffrey J Pretto, Philip J Morgan, Robin Callister, Lisa G Wood
A prospective cohort study of the long-term effects of CPAP on carotid artery intima-media thickness in Obstructive sleep apnea syndrome
David S Hui, Qing Shang, Fanny W Ko, Susanna S Ng, Cheuk-Chun Szeto, Jenny Ngai, Alvin H Tung, Kin-Wang To, Tat-On Chan, Cheuk-Man Yu
Transient receptor potential genes, smoking, occupational exposures and cough in adults
Lidwien AM Smit, Manolis Kogevinas, Josep M Antó, Emmanuelle Bouzigon, Juan Ramón González, Nicole Le Moual, Hans Kromhout, Anne-Elie Carsin, Isabelle Pin, Deborah Jarvis, Roel Vermeulen, Christer Janson, Joachim Heinrich, Ivo Gut, Mark Lathrop, Miguel A Valverde, Florence Demenais, Francine Kauffmann
Combination of roflumilast with a beta-2 adrenergic receptor agonist inhibits proinflammatory and profibrotic mediator release from human lung fibroblasts
Stacey L Tannheimer, Clifford D Wright, Michael Salmon
The ion channel transient receptor potential melastatin-2 does not play a role in inflammatory mouse models of chronic obstructive pulmonary diseases
Liz Hardaker, Parmjit Bahra, Benjamin Cochin de Billy, Mark Freeman, Natalia Kupfer, Daniel Wyss, Alexandre Trifilieff
Bacteria in sputum of stable severe asthma and increased airway wall thickness
Qingling Zhang, Rowland Illing, Christopher K Hui, Kate Downey, Denis Carr, Martin Stearn, Khalid Alshafi, Andrew Menzies-Gow, Nanshan Zhong, Kian Fan Chung
Evidence for local dendritic cell activation in pulmonary sarcoidosis
Bregje Ten Berge, Alex KleinJan, Femke Muskens, Hamida Hammad, Henk C Hoogsteden, Rudi W Hendriks, Bart N Lambrecht, Bernt Van den Blink
Characterization of proximal pulmonary arterial cells from chronic thromboembolic pulmonary hypertension patients
Rozenn Quarck, Marijke Wynants, Alicja Ronisz, Maria Rosario Sepulveda, Frank Wuytack, Dirk Van Raemdonck, Bart Meyns, Marion Delcroix
Occupation and three-year incidence of respiratory symptoms and lung function decline: the ARIC Study
Maria C Mirabelli, Stephanie J London, Luenda E Charles, Lisa A Pompeii, Lynne E Wagenknecht
Donor lung derived myeloid and plasmacytoid dendritic cells differentially regulate T cell proliferation and cytokine production
Heather L Benson, Hidemi Suzuki, Jeremy Lott, Amanda Jo Fisher, Crystal Walline, Kathleen M Heidler, Randy Brutkiewicz, Janice S Blum, David S Wilkes
Oxidative stress induced Interleukin-32 mRNA expression in human bronchial epithelial cells
Megumi Kudo, Emiko Ogawa, Daisuke Kinose, Akane Haruna, Tamaki Takahashi, Naoya Tanabe, Satoshi Marumo, Yuma Hoshino, Toyohiro Hirai, Hiroaki Sakai, Shigeo Muro, Hiroshi Date, Michiaki Mishima
Mechanical ventilation with high tidal volumes attenuates myocardial dysfunction by decreasing cardiac edema in a rat model of LPS-induced peritonitis
Lonneke Smeding, Frans B Plötz, Regis R Lamberts, Willem J van der Laarse, Martin CJ Kneyber, AB Johan Groeneveld
Regulation of ENaC-mediated alveolar fluid clearance by insulin via PI3K/Akt pathway in LPS-induced acute lung injury
Wang Deng, Chang-Yi Li, Jin Tong, Wei Zhang, Dao-Xin Wang
Risk factors for morbidity and death in non-cystic fibrosis bronchiectasis: a retrospective cross-sectional analysis of CT diagnosed bronchiectatic patients
Pieter Christian Goeminne, Hans Scheers, Ann Decraene, Sven Seys, Lieven Joseph Dupont
The counter regulatory response induced by CpG oligonucleotides prevents bleomycin induced pneumopathy
Takeshi Kinjo, Koji Tomaru, Diana C Haines, Dennis M Klinman
Hyperoxia disrupts pulmonary epithelial barrier in newborn rats via the deterioration of occludin and ZO-1
Kai You, Xuewen Xu, Jianhua Fu, Shuyan Xu, Xiaohong Yue, Zhiling Yu, Xindong Xue
Drug-induced interstitial lung disease: mechanisms and best diagnostic approaches
Osamu Matsuno
Inhaled fluticasone propionate impairs pulmonary clearance of Klebsiella Pneumoniae in mice
Craig M Patterson, Richard L Morrison, Alain D’Souza, Xu S Teng, Kyle I Happel
Step-down from high dose fixed combination therapy in asthma patients: a randomized controlled trial
Alberto Papi, Gabriele Nicolini, Nunzio Crimi, Leonardo Fabbri, Dario Olivieri, Andrea Rossi, Pierluigi Paggiaro
Clinical utility of diagnostic guidelines and putative biomarkers in lymphangioleiomyomatosis
William YC Chang, Jennifer L Cane, John D Blakey, Maruti Kumaran, Kate S Pointon, Simon R Johnson
Rituximab therapy in pulmonary alveolar proteinosis improves alveolar macrophage lipid homeostasis
Anagha Malur, Mani S Kavuru, Irene Marshall, Barbara P Barna, Isham Huizar, Reema Karnekar, Mary Jane Thomassen
HIF-1 expression is associated with CCL2 chemokine expression in airway inflammatory cells: implications in allergic airway inflammation
Guillermina J Baay-Guzman, Ilona G Bebenek, Michelle Zeidler, Rogelio Hernandez-Pando, Mario I Vega, Eduardo A Garcia-Zepeda, Gabriela Antonio-Andres, Benjamin Bonavida, Marc Riedl, Eric Kleerup, Donald P Tashkin, Oliver Hankinson, Sara Huerta-Yepez
Comparison of the variability of the annual rates of change in FEV1 determined from serial measurements of the pre- versus post-bronchodilator FEV1 over 5 years in mild to moderate COPD: Results of the lung health study
Donald P Tashkin, He-Jing Wang, David Halpin, Eric C Kleerup, John Connett, Ning Li, Robert Elashoff
The prevalence and identity of Chlamydia -specific IgE in children with asthma and other chronic respiratory symptoms
Katir K Patel, Erica Anderson, Paul S Salva, Wilmore C Webley
Effect of β2-adrenergic receptor gene (ADRB2) 3′ untranslated region polymorphisms on inhaled corticosteroid/long-acting β2-adrenergic agonist response
Helen J Ambrose, Rachael M Lawrance, Carl J Cresswell, Mitchell Goldman, Deborah A Meyers, Eugene R Bleecker
Increased plasma mannose binding lectin levels are associated with bronchiolitis obliterans after lung transplantation
Steven J Budd, Robert M Aris, Ayorinde A Medaiyese, Stephen L Tilley, Isabel P Neuringer
Synergistic protection against hyperoxia-induced lung injury by neutrophils blockade and EC-SOD overexpression
Jae H Min, Champa N Codipilly, Sonya Nasim, Edmund J Miller, Mohamed N Ahmed
A mathematical reason for FEV1/FVC dependence on age
Tomasz Gólczewski, Wojciech Lubiński, Andrzej Chciałowski
Longitudinal inspiratory capacity changes in chronic obstructive pulmonary disease
Bartolome R Celli, Marc Decramer, Theodore Lystig, Steven Kesten, Donald P Tashkin
Differential effects of simvastatin on IL-13-induced cytokine gene expression in primary mouse tracheal epithelial cells
Amir A Zeki, Phil Thai, Nicholas J Kenyon, Reen Wu
GOLD or lower limit of normal definition? a letter and authors’ response
Philip Quanjer, Carlos A Vaz Fragoso, Martin R Miller, Gülmisal Güder, Stefan Störk, Arno W Hoes, Frans Rutten
Airway responses and inflammation in subjects with asthma after four days of repeated high-single-dose allergen challenge
Johannes Schulze, Sandra Voss, Ulrich Zissler, Markus A Rose, Stefan Zielen, Ralf Schubert
25-hydroxycholesterol enhances cytokine release and toll-like receptor 3 response in airway epithelial cells
Akira Koarai, Satoru Yanagisawa, Hisatoshi Sugiura, Tomohiro Ichikawa, Takashi Kikuchi, Kanako Furukawa, Keiichiro Akamatsu, Tsunahiko Hirano, Masanori Nakanishi, Kazuto Matsunaga, Yoshiaki Minakata, Masakazu Ichinose
Clinical trial design in chronic obstructive pulmonary disease: current perspectives and considerations with regard to blinding of tiotropium
Kai-Michael Beeh, Jutta Beier, James F Donohue
Measurement of asthma control according to global initiative for asthma guidelines: a comparison with the asthma control questionnaire
José María Olaguibel, Santiago Quirce, Berta Juliá, Cristina Fernández, Ana María Fortuna, Jesús Molina, Vicente Plaza
A Newfoundland cohort of familial and sporadic idiopathic pulmonary fibrosis patients: clinical and genetic features
Bridget A Fernandez, George Fox, Rick Bhatia, Eric Sala, Barbara Noble, Nash Denic, Dzintra Fernandez, Nigel Duguid, Amanda Dohey, Fady Kamel, Laura Edwards, Krista Mahoney, Susan Stuckless, Patrick S Parfrey, Michael O Woods
The effect of budesonide/formoterol maintenance and reliever therapy on the risk of severe asthma exacerbations following episodes of high reliever use: an exploratory analysis of two randomised, controlled studies with comparisons to standard therapy
Roland Buhl, Piotr Kuna, Matthew J Peters, Tomas LG Andersson, Ian P Naya, Stefan Peterson, Klaus F Rabe
Pulmonary hypertension in patients with Martorell hypertensive leg ulcer: a case control study
Leonardo Glutz von Blotzheim, Felix C Tanner, Georg Noll, Matthias Brock, Manuel Fischler, Jürg Hafner, Rudolf Speich, Silvia Ulrich, Lars C Huber
Emphysema distribution and annual changes in pulmonary function in male patients with chronic obstructive pulmonary disease
Naoya Tanabe, Shigeo Muro, Shiro Tanaka, Susumu Sato, Tsuyoshi Oguma, Hirofumi Kiyokawa, Tamaki Takahashi, Daisuke Kinose, Yuma Hoshino, Takeshi Kubo, Emiko Ogawa, Toyohiro Hirai, Michiaki Mishima
Maternal smoking and the retinoid pathway in the developing lung
Sara E Manoli, Lacey A Smith, Carrie A Vyhlidal, Chang Hyeok An, Yolanda Porrata, Wellington V Cardoso, Rebecca M Baron, Kathleen J Haley
WNT7B in fibroblastic foci of idiopathic pulmonary fibrosis
Travis Meuten, Ariel Hickey, Katherine Franklin, Brian Grossi, Jeremy Tobias, Donna R Newman, Samuel H Jennings, Maria Correa, Philip L Sannes
Vibration response imaging: a novel noninvasive tool for evaluating the initial therapeutic effect of noninvasive positive pressure ventilation in patients with acute exacerbation of chronic obstructive pulmonary disease
Dai Bing, Kang Jian, Sun Long-feng, Tan Wei, Zhao Hong-wen
TNF-α is associated with loss of lean body mass only in already cachectic COPD patients
Tomas ML Eagan, Esteban C Gabazza, Corina D’Alessandro-Gabazza, Paloma Gil-Bernabe, Shinya Aoki, Jon A Hardie, Per S Bakke, Peter D Wagner
Non-typeable Haemophilus influenzae decreases cilia beating via protein kinase C epsilon
Kristina L Bailey, Tricia D LeVan, Daniel A Yanov, Jaqueline A Pavlik, Jane M DeVasure, Joseph H Sisson, Todd A Wyatt
Resistin-like molecule alpha1 (Fizz1) recruits lung dendritic cells without causing pulmonary fibrosis
Satish K Madala, Ramakrishna Edukulla, Katy R Davis, Stephanie Schmidt, Cynthia Davidson, Joseph A Kitzmiller, William D Hardie, Thomas R Korfhagen
L-citrulline supplementation reverses the impaired airway relaxation in neonatal rats exposed to hyperoxia
Ramadan B Sopi, Syed IA Zaidi, Mitko Mladenov, Hazbije Sahiti, Zahide Istrefi, Icko Gjorgoski, Azem Lajçi, Muharrem Jakupaj
Repeated intranasal TLR7 stimulation reduces allergen responsiveness in allergic rhinitis
Lennart Greiff, Anders Cervin, Cecilia Ahlström-Emanuelsson, Gun Almqvist, Morgan Andersson, Jan Dolata, Leif Eriksson, Edward Högestätt, Anders Källén, Per Norlén, Inga-Lisa Sjölin, Henrik Widegren
Increased human Ca2+-activated Cl-channel 1 expression and mucus overproduction in airway epithelia of smokers and chronic obstructive pulmonary disease patients
Hiroki Iwashita, Keisaku Fujimoto, Shigeru Morita, Atsushi Nakanishi, Keishi Kubo
Airway protease/antiprotease imbalance in atopic asthmatics contributes to increased Influenza A virus cleavage and replication
Matthew J Kesic, Michelle Hernandez, Ilona Jaspers
Detection of Pseudomonas aeruginosa in sputum headspace through volatile organic compound analysis
Pieter C Goeminne, Thomas Vandendriessche, Johan Van Eldere, Bart M Nicolai, Maarten LATM Hertog, Lieven J Dupont
Lipoteichoic acid induces surfactant protein-A biosynthesis in human alveolar type II epithelial cells through activating the MEK1/2-ERK1/2-NF-κB pathway
Feng-Lin Liu, Chi-Yuan Chuang, Yu-Ting Tai, Hsiu-Lien Tang, Tyng-Guey Chen, Ta-Liang Chen, Ruei-Ming Chen
Observational study of the outcomes and costs of initiating maintenance therapies in patients with moderate exacerbations of COPD
Anand A Dalal, Manan B Shah, Anna O D’Souza, Orsolya E Lunacsek, Saurabh P Nagar, Glenn D Crater
A predictive scoring instrument for tuberculosis lost to follow-up outcome
Teresa Rodrigo, Joan A Caylà, Martí Casals, José Mª García-García, José A Caminero, Juan Ruiz-Manzano, Rafael Blanquer, Rafael Vidal, Neus Altet, José L Calpe, Antón Penas
A low resting heart rate at diagnosis predicts favourable long-term outcome in pulmonary arterial and chronic thromboembolic pulmonary hypertension. A prospective observational study
Florian F Hildenbrand, Ivan Fauchère, Lars C Huber, Stephan Keusch, Rudolf Speich, Silvia Ulrich
Prediction and course of symptoms and lung function around an exacerbation in chronic obstructive pulmonary disease
Maarten van den Berge, Wim CJ Hop, Thys van der Molen, Jan A van Noord, Jacques PHM Creemers, Ad JM Schreurs, Emiel FM Wouters, Dirkje S Postma
Inflammatory and repair serum biomarker pattern. Association to clinical outcomes in COPD
Victor Pinto-Plata, Ciro Casanova, Hana Müllerova, Juan P de Torres, Henneth Corado, Nerea Varo, Elizabeth Cordoba, Salah Zeineldine, Hildegarde Paz, Rebeca Baz, Miguel Divo, Felipe Cortopassi, Bartolome R Celli
Vitamin D supplementation during rehabilitation in COPD: a secondary analysis of a randomized trial
Miek Hornikx, Hans Van Remoortel, An Lehouck, Chantal Mathieu, Karen Maes, Ghislaine Gayan-Ramirez, Marc Decramer, Thierry Troosters, Wim Janssens
Heterogeneity of respiratory dendritic cell subsets and lymphocyte populations in inbred mouse strains
Holger Hackstein, Andreas Wachtendorf, Sabine Kranz, Jürgen Lohmeyer, Gregor Bein, Nelli Baal
Nitric oxide-induced eosinophil apoptosis is dependent on mitochondrial permeability transition (mPT), JNK and oxidative stress: apoptosis is preceded but not mediated by early mPT-dependent JNK activation
Pinja Ilmarinen-Salo, Eeva Moilanen, Vuokko L Kinnula, Hannu Kankaanranta
NT-proBNP independently predicts long term mortality after acute exacerbation of COPD – a prospective cohort study
Arne Didrik Høiseth, Torbjørn Omland, Tor-Arne Hagve, Pål H Brekke, Vidar Søyseth
Transbronchial biopsy is useful in predicting UIP pattern
Sara Tomassetti, Alberto Cavazza, Thomas V Colby, Jay H Ryu, Oriana Nanni, E Scarpi, Paola Tantalocco, Matteo Buccioli, Alessandra Dubini, Sara Piciucchi, Claudia Ravaglia, Christian Gurioli, Gian Luca Casoni, Carlo Gurioli, Micaela Romagnoli, Venerino Poletti
Fas-deficient mice have impaired alveolar neutrophil recruitment and decreased expression of anti-KC autoantibody:KC complexes in a model of acute lung injury
Sucheol Gil, Alex W Farnand, William A Altemeier, Sean E Gill, Anna Kurdowska, Agnieszka Krupa, Jon M Florence, Gustavo Matute-Bello
Low intensity, long-term outpatient rehabilitation in COPD: a randomised controlled trial
Hans Jörg Baumann, Stefan Kluge, Katrin Rummel, Hans Klose, Jan K Hennigs, Tibor Schmoller, Andreas Meyer
Thiazolidinediones inhibit airway smooth muscle release of the chemokine CXCL10: in vitro comparison with current asthma therapies
Petra Seidel, Hatem Alkhouri, Daniel J Lalor, Janette K Burgess, Carol L Armour, J Margaret Hughes
Transformation of adrenal medullary chromaffin cells increases asthmatic susceptibility in pups from allergen-sensitized rats
Jun-Tao Feng, Xiu-Ming Wu, Xiao-Zhao Li, Ye-Qiang Zou, Ling Qin, Cheng-Ping Hu
The dendritic cell niche in chronic obstructive pulmonary disease
Angela Haczku
Heterozygosity for E292V in ABCA3, lung function and COPD in 64,000 individuals
Marie Bækvad-Hansen, Børge G Nordestgaard, Morten Dahl
HSULF-1 inhibits ERK and AKT signaling and decreases cell viability in vitro in human lung epithelial cells
Huiying Zhang, Donna R Newman, Philip L Sannes
Exhaled volatile organic compounds for phenotyping chronic obstructive pulmonary disease: a cross-sectional study
Maria Basanta, Baharudin Ibrahim, Rachel Dockry, David Douce, Mike Morris, Dave Singh, Ashley Woodcock, Stephen J Fowler
Low tidal volume protects pulmonary vasomotor function from “second-hit” injury in acute lung injury rats
Chun Pan, Jianqiang Wang, Wei Liu, Ling Liu, Liang Jing, Yi Yang, Haibo Qiu
Functional characterization of the matrix metalloproteinase-1 cigarette smoke-responsive region and association with the lung health study
Alison M Wallace, Becky A Mercer, Jianqing He, Robert F Foronjy, Domenico Accili, Andrew J Sandford, Peter D Paré, Jeanine M D’Armiento
Leaky lysosomes in lung transplant macrophages: azithromycin prevents oxidative damage
H L Persson, Linda K Vainikka, Maria Sege, Urban Wennerström, Sören Dam-Larsen, Jenny Persson
How air pollution influences clinical management of respiratory diseases. A case-crossover study in Milan
Pierachille Santus, Antonio Russo, Enzo Madonini, Luigi Allegra, Francesco Blasi, Stefano Centanni, Antonio Miadonna, Gianfranco Schiraldi, Sandro Amaducci
Hypoxia-induced DNA hypermethylation in human pulmonary fibroblasts is associated with Thy-1 promoter methylation and the development of a pro-fibrotic phenotype
Claire M Robinson, Roisin Neary, Ashleigh Levendale, Chris J Watson, John A Baugh
Cigarette smoke-induced accumulation of lung dendritic cells is interleukin-1α-dependent in mice
Fernando M Botelho, Jake K Nikota, Carla MT Bauer, Mathieu C Morissette, Yoichiro Iwakura, Roland Kolbeck, Donna Finch, Alison A Humbles, Martin R Stämpfli
Analysis of longitudinal changes in dyspnea of patients with chronic obstructive pulmonary disease: an observational study
Toru Oga, Mitsuhiro Tsukino, Takashi Hajiro, Akihiko Ikeda, Koichi Nishimura
Nrf2 protects human alveolar epithelial cells against injury induced by influenza A virus
Beata Kosmider, Elise M Messier, William J Janssen, Piruz Nahreini, Jieru Wang, Kevan L Hartshorn, Robert J Mason
Repair of tracheal epithelium by basal cells after chlorine-induced injury
Sadiatu Musah, Jing Chen, Gary W Hoyle
Effects of guaifenesin, N-acetylcysteine, and ambroxol on MUC5AC and mucociliary transport in primary differentiated human tracheal-bronchial cells
JeanClare Seagrave, Helmut H Albrecht, David B Hill, Duncan F Rogers, Gail Solomon
Gene expression analysis of a murine model with pulmonary vascular remodeling compared to end-stage IPAH lungs
Kayoko Shimodaira, Yoichiro Okubo, Eri Ochiai, Haruo Nakayama, Harutaka Katano, Megumi Wakayama, Minoru Shinozaki, Takao Ishiwatari, Daisuke Sasai, Naobumi Tochigi, Tetsuo Nemoto, Tsutomu Saji, Katsuhiko Kamei, Kazutoshi Shibuya
Snail promotes an invasive phenotype in lung carcinoma
Heta Merikallio, Taina Turpeenniemi-Hujanen, Paavo Pääkkö, Riitta Mäkitaro, Kaarteenaho Riitta, Sirpa Salo, Tuula Salo, Terttu Harju, Ylermi Soini
Differential effects of formoterol on thrombin- and PDGF-induced proliferation of human pulmonary arterial vascular smooth muscle cells
Elena A Goncharova, Irene S Khavin, Dmitry A Goncharov, Vera P Krymskaya
Resolvin D1 attenuates inflammation in lipopolysaccharide-induced acute lung injury through a process involving the PPARγ/NF-κB pathway
Zenglin Liao, Jiajia Dong, Wei Wu, Ting Yang, Tao Wang, Lingli Guo, Lei Chen, Dan Xu, Fuqiang Wen
Gene expression profiling following NRF2 and KEAP1 siRNA knockdown in human lung fibroblasts identifies CCL11/Eotaxin-1 as a novel NRF2 regulated gene
Jimmy Fourtounis, I-Ming Wang, Marie-Claude Mathieu, David Claveau, Tenneille Loo, Aimee L Jackson, Mette A Peters, Alex G Therien, Yves Boie, Michael A Crackower
Strain variation in response to lung ischemia: role of MMP-12
Clarke G Tankersley, Aigul Moldobaeva, Elizabeth M Wagner
The effect of lipoprotein-associated phospholipase A2 deficiency on pulmonary allergic responses in aspergillus fumigatus sensitized mice
Zhilong Jiang, Melane L Fehrenbach, Giulia Ravaioli, Blerina Kokalari, Imre G Redai, Steven A Sheardown, Stephen Wilson, Colin Macphee, Angela Haczku
An investigation of the resolution of inflammation (catabasis) in COPD
Aina Noguera, Cristina Gomez, Rosa Faner, Borja Cosio, Ana González-Périz, Joan Clària, Angel Carvajal, Alvar Agustí
Cleaved cytokeratin-18 is a mechanistically informative biomarker in idiopathic pulmonary fibrosis
Seung-Ick Cha, Christopher J Ryerson, Joyce S Lee, Jasleen Kukreja, Sophia S Barry, Kirk D Jones, Brett M Elicker, Dong Soon Kim, Feroz R Papa, Harold R Collard, Paul J Wolters
The association of down-regulated toll-like receptor 4 expression with airflow limitation and emphysema in smokers
Sei Won Lee, Dal Rae Kim, Tae Jung Kim, Jin Ho Paik, Jin-Haeng Chung, Sanghoon Jheon, Jin Won Huh, Jae-Ho Lee, Choon-Taek Lee
Statins as potential therapeutic drug for asthma?
Cheng Yuan, Lin Zhou, Jiyun Cheng, Jingying Zhang, Yue Teng, Mao Huang, Ian M Adcock, Peter J Barnes, Xin Yao
1-year prospective real life monitoring of asthma control and quality of life in Italy
Claudio Terzano, Giovanni Cremonesi, Giuseppe Girbino, Eleonora Ingrassia, Serafino Marsico, Gabriele Nicolini, Luigi Allegra
Specific IgA and metalloproteinase activity in bronchial secretions from stable chronic obstructive pulmonary disease patients colonized by Haemophilus influenzae
Laura Millares, Alicia Marin, Judith Garcia-Aymerich, Jaume Sauleda, José Belda, Eduard Monsó
Elevated cardiovascular risk among adults with obstructive and restrictive airway functioning in the United States: a cross-sectional study of the National Health and Nutrition Examination Survey from 2007–2010
Earl S Ford, Anne G Wheaton, David M Mannino, Letitia Presley-Cantrell, Chaoyang Li, Janet B Croft
Patient-reported outcomes to assess the efficacy of extended-release guaifenesin for the treatment of acute respiratory tract infection symptoms
Helmut Albrecht, Margaret Vernon, Gail Solomon
Clinical use of exhaled volatile organic compounds in pulmonary diseases: a systematic review
Kim DG van de Kant, Linda JTM van der Sande, Quirijn Jöbsis, Onno CP van Schayck, Edward Dompeling
Ultrasound assessment of lower limb muscle mass in response to resistance training in COPD
Manoj K Menon, Linzy Houchen, Samantha Harrison, Sally J Singh, Michael D Morgan, Michael C Steiner
Stage-dependent association of BDNF and TGF-β1with lung function in stable COPD
Paul Stoll, Urs Wuertemberger, Kai Bratke, Christiana Zingler, J Christian Virchow, Marek Lommatzsch
Prevention of airway hyperresponsiveness induced by left ventricular dysfunction in rats
Ferenc Petak, Gergely Albu, Eniko Lele, Maurice Beghetti, Walid Habre
Can spirometric norms be set using pre- or post- bronchodilator test results in older people?
Bernet Kato, Amund Gulsvik, William Vollmer, Christer Janson, Michael Studnika, Sonia Buist, Peter Burney
The prognostic value of pulmonary embolism severity index in acute pulmonary embolism: a meta-analysis
Xiao-Yu Zhou, Su-Qin Ben, Hong-Lin Chen, Song-Shi Ni
Individuals with increased inflammatory response to ozone demonstrate muted signaling of immune cell trafficking pathways
Rebecca C Fry, Julia E Rager, Haibo Zhou, Baiming Zou, June W Brickey, Jenny Ting, John C Lay, David B Peden, Neil E Alexis