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Endocrine
Published in: Endocrine 3/2021

01-06-2021 | Refractive Errors | Research Letter

Ocular morphology development and function in children with congenital hypothyroidism diagnosed by neonatal screening

Authors: Angelo Tropeano, Anna Maria Roszkowska, Tommaso Aversa, Domenico Corica, Giorgia Pepe, Pasquale Aragona, Malgorzata Wasniewska

Published in: Endocrine | Issue 3/2021

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Excerpt

The ocular globe, as part of the central nervous system, is vulnerable to the lack of appropriate thyroid hormones (THs) levels especially during a period of active and rapid growth named “brain growth spurt”, which endures in early postnatal life [1]. In animal models of congenital hypothyroidism (CH), THs have shown a crucial function in craniofacial and eye development. In particular, corneal maturation, in terms of light transmission and epithelial development, as well as retinal thickness and layering, have been related to THs levels [1‐5]. …
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Metadata
Title
Ocular morphology development and function in children with congenital hypothyroidism diagnosed by neonatal screening
Authors
Angelo Tropeano
Anna Maria Roszkowska
Tommaso Aversa
Domenico Corica
Giorgia Pepe
Pasquale Aragona
Malgorzata Wasniewska
Publication date
01-06-2021
Publisher
Springer US
Published in
Endocrine / Issue 3/2021
Print ISSN: 1355-008X
Electronic ISSN: 1559-0100
DOI
https://doi.org/10.1007/s12020-020-02457-4

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