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Published in: World Journal of Surgical Oncology 1/2016

Open Access 01-12-2016 | Case report

Primary undifferentiated pleomorphic sarcoma of the breast in a young female: a case report

Authors: Banushree C. Srinivasamurthy, Ambedkar Raj Kulandaivelu, Kaushik Saha, Arpita Saha

Published in: World Journal of Surgical Oncology | Issue 1/2016

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Abstract

Background

Undifferentiated pleomorphic sarcoma is a rare entity and requires extensive immunohistochemical markers to differentiate it from other tumors of the breast.

Case presentation

We present a 29-year-old female with a left breast lump for 2 months. Initial diagnosis of malignant spindle cell tumor was done on core biopsy following which total mastectomy was done. After extensive sampling, on histology, highly pleomorphic spindle cells palisading the area of geographic necrosis with very high atypical mitosis were seen. As there was diagnostic difficulty, immunohistochemical antibody panel was used and diagnosis of undifferentiated pleomorphic sarcoma of the breast was made by exclusion.

Conclusions

Core biopsy with immunostaining is possibly superior to FNA as an initial diagnostic modality for breast masses with atypical features.
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Metadata
Title
Primary undifferentiated pleomorphic sarcoma of the breast in a young female: a case report
Authors
Banushree C. Srinivasamurthy
Ambedkar Raj Kulandaivelu
Kaushik Saha
Arpita Saha
Publication date
01-12-2016
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2016
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/s12957-016-0947-9

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