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Published in: Medical Oncology 4/2012

01-12-2012 | Case Report

Primary mantle cell lymphoma of the trachea

Authors: Achuta K. Guddati, Creticus P. Marak

Published in: Medical Oncology | Issue 4/2012

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Abstract

Primary mantle cell lymphoma (MCL) is a controversial entity. It is difficult to diagnose MCL in a single organ without lymph node involvement. However, with the advent of PET-CT scans and large panels of immunohistochemistry markers, there have been increasing reports of primary MCL detected in various organs of which the GI tract is the most common. In this case report, we describe the diagnosis and clinical course of a patient who presented with “B symptoms” and respiratory distress. On further investigation, he was found to have a mass in his trachea, which was diagnosed as primary MCL.
Literature
1.
go back to reference Banks PM, Chan J, Cleary ML, et al. Mantle cell lymphoma. A proposal for unification of morphologic, immunologic, and molecular data. Am J Surg Pathol. 1992;16:637–40.PubMedCrossRef Banks PM, Chan J, Cleary ML, et al. Mantle cell lymphoma. A proposal for unification of morphologic, immunologic, and molecular data. Am J Surg Pathol. 1992;16:637–40.PubMedCrossRef
2.
go back to reference Jaffe ES, Harris NL, Diebold J, Muller-Hermelink HK. World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues. A progress report. Am J Clin Pathol. 1999;111:S8–12.PubMed Jaffe ES, Harris NL, Diebold J, Muller-Hermelink HK. World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues. A progress report. Am J Clin Pathol. 1999;111:S8–12.PubMed
3.
go back to reference Hunt KE, Reichard KK, Wilson CS. Mantle cell lymphoma lacking the t(11;14) translocation: a case report and brief review of the literature. J Clin Pathol. 2008;61:869–70.PubMedCrossRef Hunt KE, Reichard KK, Wilson CS. Mantle cell lymphoma lacking the t(11;14) translocation: a case report and brief review of the literature. J Clin Pathol. 2008;61:869–70.PubMedCrossRef
4.
go back to reference Fu K, Weisenburger DD, Greiner TC, et al. Cyclin D1-negative mantle cell lymphoma: a clinicopathologic study based on gene expression profiling. Blood. 2005;106:4315–21.PubMedCrossRef Fu K, Weisenburger DD, Greiner TC, et al. Cyclin D1-negative mantle cell lymphoma: a clinicopathologic study based on gene expression profiling. Blood. 2005;106:4315–21.PubMedCrossRef
5.
go back to reference Yatabe Y, Suzuki R, Tobinai K, et al. Significance of cyclin D1 overexpression for the diagnosis of mantle cell lymphoma: a clinicopathologic comparison of cyclin D1-positive MCL and cyclin D1-negative MCL-like B-cell lymphoma. Blood. 2000;95:2253–61.PubMed Yatabe Y, Suzuki R, Tobinai K, et al. Significance of cyclin D1 overexpression for the diagnosis of mantle cell lymphoma: a clinicopathologic comparison of cyclin D1-positive MCL and cyclin D1-negative MCL-like B-cell lymphoma. Blood. 2000;95:2253–61.PubMed
6.
go back to reference Weigert O, Unterhalt M, Hiddemann W, Dreyling M. Mantle cell lymphoma: state-of-the-art management and future perspective. Leuk Lymphoma. 2009;50:1937–50.PubMedCrossRef Weigert O, Unterhalt M, Hiddemann W, Dreyling M. Mantle cell lymphoma: state-of-the-art management and future perspective. Leuk Lymphoma. 2009;50:1937–50.PubMedCrossRef
7.
go back to reference Romaguera JE, Medeiros LJ, Hagemeister FB, et al. Frequency of gastrointestinal involvement and its clinical significance in mantle cell lymphoma. Cancer. 2003;97:586–91.PubMedCrossRef Romaguera JE, Medeiros LJ, Hagemeister FB, et al. Frequency of gastrointestinal involvement and its clinical significance in mantle cell lymphoma. Cancer. 2003;97:586–91.PubMedCrossRef
8.
go back to reference Saxman S, Righi P. Mantle cell lymphoma appearing as a tongue base mass. Ear Nose Throat J. 1997;76:35–6.PubMed Saxman S, Righi P. Mantle cell lymphoma appearing as a tongue base mass. Ear Nose Throat J. 1997;76:35–6.PubMed
9.
go back to reference Licci S, Morelli L, Covello R. Primary mantle cell lymphoma of the testis. Ann Hematol. 2011;90:483–4.PubMedCrossRef Licci S, Morelli L, Covello R. Primary mantle cell lymphoma of the testis. Ann Hematol. 2011;90:483–4.PubMedCrossRef
10.
go back to reference Aspiotis M, Gorezis S, Asproudis I, et al. Primary mantle cell lymphoma of the conjunctiva: a case report. Virchows Arch. 2006;449:472–5.PubMedCrossRef Aspiotis M, Gorezis S, Asproudis I, et al. Primary mantle cell lymphoma of the conjunctiva: a case report. Virchows Arch. 2006;449:472–5.PubMedCrossRef
11.
go back to reference Ferry JA, Fung CY, Zukerberg L, et al. Lymphoma of the ocular adnexa: a study of 353 cases. Am J Surg Pathol. 2007;31:170–84.PubMedCrossRef Ferry JA, Fung CY, Zukerberg L, et al. Lymphoma of the ocular adnexa: a study of 353 cases. Am J Surg Pathol. 2007;31:170–84.PubMedCrossRef
12.
go back to reference Sen F, Medeiros LJ, Lu D, et al. Mantle cell lymphoma involving skin: cutaneous lesions may be the first manifestation of disease and tumors often have blastoid cytologic features. Am J Surg Pathol. 2002;26:1312–8.PubMedCrossRef Sen F, Medeiros LJ, Lu D, et al. Mantle cell lymphoma involving skin: cutaneous lesions may be the first manifestation of disease and tumors often have blastoid cytologic features. Am J Surg Pathol. 2002;26:1312–8.PubMedCrossRef
13.
go back to reference Estrozi B, Sanches JA Jr, Varela PC, Bacchi CE. Primary cutaneous blastoid mantle cell lymphoma-case report. Am J Dermatopathol. 2009;31:398–400.PubMedCrossRef Estrozi B, Sanches JA Jr, Varela PC, Bacchi CE. Primary cutaneous blastoid mantle cell lymphoma-case report. Am J Dermatopathol. 2009;31:398–400.PubMedCrossRef
14.
go back to reference Zattra E, Zambello R, Marino F, Bordignon M, Alaibac M. Primary cutaneous mantle cell lymphoma. Acta Derm Venereol. 2011;91:474–5.PubMedCrossRef Zattra E, Zambello R, Marino F, Bordignon M, Alaibac M. Primary cutaneous mantle cell lymphoma. Acta Derm Venereol. 2011;91:474–5.PubMedCrossRef
15.
go back to reference Ziepert M, Hasenclever D, Kuhnt E, et al. Standard International prognostic index remains a valid predictor of outcome for patients with aggressive CD20+ B-cell lymphoma in the rituximab era. J Clin Oncol. 2010;28:2373–80.PubMedCrossRef Ziepert M, Hasenclever D, Kuhnt E, et al. Standard International prognostic index remains a valid predictor of outcome for patients with aggressive CD20+ B-cell lymphoma in the rituximab era. J Clin Oncol. 2010;28:2373–80.PubMedCrossRef
Metadata
Title
Primary mantle cell lymphoma of the trachea
Authors
Achuta K. Guddati
Creticus P. Marak
Publication date
01-12-2012
Publisher
Springer US
Published in
Medical Oncology / Issue 4/2012
Print ISSN: 1357-0560
Electronic ISSN: 1559-131X
DOI
https://doi.org/10.1007/s12032-012-0199-7

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