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31-07-2022 | Preterm Labor | Topic Paper

A comparison of adverse pregnancy events between ureteral stents and percutaneous nephrostomy tubes in the treatment of nephrolithiasis during pregnancy: A propensity score-matched analysis of a large multi-institutional research network

Authors: Matthew M. Mason, Sirpi Nackeeran, Soum Lokeshwar, Marisa R. Carino Mason, Taylor Kohn, Hemendra N. Shah, Ranjith Ramasamy

Published in: World Journal of Urology | Issue 7/2023

Abstract

Purpose

To investigate rates of adverse pregnancy events associated with the use of percutaneous nephrostomy tubes (PCN) versus ureteral stents in the treatment of nephrolithiasis during pregnancy.

Methods

We queried the TriNetX Diamond Network database to evaluate pregnant women (ICD-10 Z34, O09) with a history of nephrolithiasis (N20-23) who underwent a PCN (CPT 50432) or ureteral stent (52332) placement up to 6 months before delivery (O80-82). We controlled for the following potentially confounding variables through propensity score matching: age, race, ethnicity, acute pyelonephritis (N10), infections of the genitourinary tract in pregnancy (O23.0), and other sepsis (A41) at the time of stent or PCN placement.

Results

We identified 2,999 pregnant women who underwent ureteral stent placement and 321 who underwent PCN. Following propensity score matching, we found there to be no significant difference in the rate of premature labor or delivery (aOR 1.08, 95% CI 0.735–1.588), premature rupture of membranes (0.889, 0.453–1.743), intrauterine infection (0.906, 0.379–2.165), or c-Sect. (0.825, 0.408–1.667). Within 6 months of their initial procedure, women with a ureteral stent experienced a significantly decreased rate of subsequent urinary tract infection (UTI) or pyelonephritis (0.52, 0.38–0.71), inpatient hospital stay (0.40, 0.26–0.64), emergency department visit (0.65, 0.48–0.89), and repeat exchange procedure (0.70, 0.51–0.96).

Conclusion

In the treatment of nephrolithiasis during pregnancy, PCN versus ureteral stent placement does not confer a significant difference in rates of adverse pregnancy events. However, ureteral stent placement was associated with a lower incidence of hospital admissions, emergency department visits, exchange procedures, and new UTIs or pyelonephritis.

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Title: A comparison of adverse pregnancy events between ureteral stents and percutaneous nephrostomy tubes in the treatment of nephrolithiasis during pregnancy: A propensity score-matched analysis of a large multi-institutional research network
Authors: Matthew M. Mason
Sirpi Nackeeran
Soum Lokeshwar
Marisa R. Carino Mason
Taylor Kohn
Hemendra N. Shah
Ranjith Ramasamy
Publication date: 31-07-2022
Publisher: Springer Berlin Heidelberg
Keywords: Preterm Labor
Premature Rupture of Membranes
Septicemia
Pyelonephritis
Septicemia
Nephrostomy
Urinary Tract Infection
Nephrostomy
Urolithiasis
Pyelonephritis
Published in: World Journal of Urology / Issue 7/2023
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI: https://doi.org/10.1007/s00345-022-04111-2

2024 ASCO Annual Meeting

Springer Medicine

A comparison of adverse pregnancy events between ureteral stents and percutaneous nephrostomy tubes in the treatment of nephrolithiasis during pregnancy: A propensity score-matched analysis of a large multi-institutional research network

Abstract

Purpose

Methods

Results

Conclusion

2024 ASCO Annual Meeting

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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