In the last decade, researchers have made a concerted effort to move beyond their restrictive silos so as to practice cross-discipline studies in ways that have led to some paradigm-shifting observations and practices. This is an exciting era of discovery as so-called system approaches become multi-system studies. The new discoveries and methods highlighted in this issue will likely expedite solutions for some of the more enigmatic diseases, such as ophthalmic and male breast cancer, for example. …
Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.