After working for the Agricultural Research Service to develop diagnostic probes for virally infected germplasm imported into the USA, Dr. Stephanie Tucker trained at the Henry Jackson Foundation in Bethesda, Maryland, where she worked on mechanisms of microbial pathogenesis of enteric bacterial pathogens. Dr. Tucker went on to graduate from Stony Brook University in New York, where she earned her doctoral degree for the identification and characterization of the type three secretion system (TTSS) of Salmonella typhimurium. Her findings suggested that the TTSS was not unique to Shigella flexneri as was previously thought and opened the door to discovering the prevalence of the TTSS as a wide-spread bacterial toxin delivery system. …
Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.