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01-01-2014 | Original Article

Potential anti-inflammatory effect of low-level laser therapy on the experimental reflux laryngitis: a preliminary study

Authors: Renata R. Marinho, Renata M. Matos, Jandson S. Santos, Maria A. G. Ribeiro, Ronaldo A. Ribeiro, Roberto C. P. Lima Jr, Ricardo L. C. Albuquerque Jr, Sara M. Thomazzi

Published in: Lasers in Medical Science | Issue 1/2014

Abstract

The most common cause of laryngitis is the laryngopharyngeal reflux disease. The symptoms of laryngitis can be hoarseness, globus, chronic cough, voice fatigue, throat pain, and dysphagia. Low-level laser therapy (LLLT) is beneficial to reduce the pain and inflammatory response without side effects. Therefore, LLLT may be a useful tool for the treatment of laryngitis. This study proposes to analyze the effect of laser therapy in a model of reflux-induced laryngitis. The animals were randomly put into three groups: control—non-intubated; nasogastric intubation—intubated; and nasogastric intubation with laser therapy—intubated treated with 105-J/cm² laser irradiation. For the induction of laryngitis, the animals were anesthetized and a nasogastric tube was inserted through the nasopharynx until it reached the stomach, for 1 week. Thereafter, measurement of myeloperoxidase activity and the histopathological procedures were performed. In conclusion, we observed in this study that 105-J/cm² infrared laser reduced the influx of neutrophils in rats, and it improved the reparative collagenization of the laryngeal tissues.

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Title: Potential anti-inflammatory effect of low-level laser therapy on the experimental reflux laryngitis: a preliminary study
Authors: Renata R. Marinho
Renata M. Matos
Jandson S. Santos
Maria A. G. Ribeiro
Ronaldo A. Ribeiro
Roberto C. P. Lima Jr
Ricardo L. C. Albuquerque Jr
Sara M. Thomazzi
Publication date: 01-01-2014
Publisher: Springer London
Published in: Lasers in Medical Science / Issue 1/2014
Print ISSN: 0268-8921
Electronic ISSN: 1435-604X
DOI: https://doi.org/10.1007/s10103-013-1323-4

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Potential anti-inflammatory effect of low-level laser therapy on the experimental reflux laryngitis: a preliminary study

Abstract

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Springer Medicine

Abstract

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