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01-01-2014 | Original Article

In vitro cell tests of pancreatic malignant tumor cells by photothermotherapy based on DMSO porous silicon colloids

Authors: Chanseok Hong, Chongmu Lee

Published in: Lasers in Medical Science | Issue 1/2014

Abstract

Dimethyl sulfoxide porous silicon (DMSO-PSi) colloid in which DMSO was used as a surfactant suitable for inhibiting the agglomeration of PSi nanoparticles was prepared for use in cancer photothermotherapy. The photothermal effect of the DMSO-PSi colloid was found to be high enough to destroy cancer cells (T = ∼52 °C). The mean particle size of the PSi nanoparticles in the DMSO-PSi colloid was 67 nm, which is low enough to flow through blood vessels without causing a blockage. The DMSO-PSi colloid in combination with an NIR laser resulted in a cell viability of 5.70 %, which is a sufficiently high cytotoxic effect.

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Title: In vitro cell tests of pancreatic malignant tumor cells by photothermotherapy based on DMSO porous silicon colloids
Authors: Chanseok Hong
Chongmu Lee
Publication date: 01-01-2014
Publisher: Springer London
Published in: Lasers in Medical Science / Issue 1/2014
Print ISSN: 0268-8921
Electronic ISSN: 1435-604X
DOI: https://doi.org/10.1007/s10103-013-1316-3

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In vitro cell tests of pancreatic malignant tumor cells by photothermotherapy based on DMSO porous silicon colloids

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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