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Open Access 01-12-2023 | Postoperative Nausea and Vomiting | Research

Risk estimation for postoperative nausea and vomiting: development and validation of a nomogram based on point-of-care gastric ultrasound

Authors: Huohu Zhong, Yingchao Liu, Piaopiao Liu, Zecheng Wang, Xihua Lian, Zhirong Xu, Ruopu Xu, Shanshan Su, Guorong Lyu, Zhenhong Xu

Published in: BMC Anesthesiology | Issue 1/2023

Abstract

Background

We aimed to develop a nomogram that can be combined with point-of-care gastric ultrasound and utilised to predict postoperative nausea and vomiting (PONV) in adult patients after emergency surgery.

Methods

Imaging and clinical data of 236 adult patients undergoing emergency surgery in a university hospital between April 2022 and February 2023 were prospectively collected. Patients were divided into a training cohort (n = 177) and a verification cohort (n = 59) in a ratio of 3:1, according to a random number table. After univariate analysis and multivariate logistic regression analysis of the training cohort, independent risk factors for PONV were screened to develop the nomogram model. The receiver operating characteristic curve, calibration curve, decision curve analysis (DCA) and clinical impact curve (CIC) were used to evaluate the prediction efficiency, accuracy, and clinical practicability of the model.

Results

Univariate analysis and multivariate logistic regression analysis showed that female sex, history of PONV, history of migraine and gastric cross-sectional area were independent risk factors for PONV. These four independent risk factors were utilised to construct the nomogram model, which achieved significant concordance indices of 0.832 (95% confidence interval [CI], 0.771–0.893) and 0.827 (95% CI, 0.722–0.932) for predicting PONV in the training and validation cohorts, respectively. The nomogram also had well-fitted calibration curves. DCA and CIC indicated that the nomogram had great clinical practicability.

Conclusions

This study demonstrated the prediction efficacy, differentiation, and clinical practicability of a nomogram for predicting PONV. This nomogram may serve as an intuitive and visual guide for rapid risk assessment in patients with PONV before emergency surgery.

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Title: Risk estimation for postoperative nausea and vomiting: development and validation of a nomogram based on point-of-care gastric ultrasound
Authors: Huohu Zhong
Yingchao Liu
Piaopiao Liu
Zecheng Wang
Xihua Lian
Zhirong Xu
Ruopu Xu
Shanshan Su
Guorong Lyu
Zhenhong Xu
Publication date: 01-12-2023
Publisher: BioMed Central
Keywords: Postoperative Nausea and Vomiting
Migraine
Vomiting
Published in: BMC Anesthesiology / Issue 1/2023
Electronic ISSN: 1471-2253
DOI: https://doi.org/10.1186/s12871-023-02345-0

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Risk estimation for postoperative nausea and vomiting: development and validation of a nomogram based on point-of-care gastric ultrasound

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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