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Open Access 29-01-2024 | Pleural Effusion | Case Report

Isolated massive pleural effusion as a manifestation of chronic graft versus host disease successfully treated with corticosteroid

Authors: Yasutaka Masuda, Sho Yamazaki, Akira Honda, Yosuke Masamoto, Mineo Kurokawa

Published in: Annals of Hematology | Issue 4/2024

Abstract

Isolated pleural effusion is a rare manifestation of chronic graft versus host disease (cGVHD) after hematopoietic stem cell transplantation (HSCT). We herein report a 58-year-old woman presenting with massive pleural effusion approximately 1 year after allogeneic HSCT, who was successfully treated with corticosteroid. She had discontinued tacrolimus approximately 1 month before she presented with pleural effusion, which was attributed to cGVHD after a thorough exclusion process. This case illustrates a unique manifestation of atypical cGVHD and highlights the need for prompt therapy initiation.

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Title: Isolated massive pleural effusion as a manifestation of chronic graft versus host disease successfully treated with corticosteroid
Authors: Yasutaka Masuda
Sho Yamazaki
Akira Honda
Yosuke Masamoto
Mineo Kurokawa
Publication date: 29-01-2024
Publisher: Springer Berlin Heidelberg
Keywords: Pleural Effusion
Graft-Versus-Host Disease
Graft-Versus-Host Disease
Stem Cell Transplantation
Stem Cell Transplantion
Stem Cell Transplantation
Tacrolimus
Published in: Annals of Hematology / Issue 4/2024
Print ISSN: 0939-5555
Electronic ISSN: 1432-0584
DOI: https://doi.org/10.1007/s00277-024-05643-w

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