Published in:
01-11-2019 | Petechiae | IM - CASE RECORD
A 29-year-old woman with persistent thrombocytopenia
Authors:
Irene Di Pasquale, Antonella Bertomoro, Fabrizio Vianello, Piero Marson, Francesca Boscaro, Fabrizio Fabris
Published in:
Internal and Emergency Medicine
|
Issue 8/2019
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Excerpt
Dr. Di Pasquale, Dr. Boscaro: In November 2013, a 29-year-old Moldovan woman was referred to our center with a platelet count of 4 × 109/L and bleeding symptoms such as epistaxis and petechiae. She had been diagnosed with immune thrombocytopenia (ITP) in 2002. Ever since her childhood, her thrombocytopenia had been associated with hemolytic anemia (Evans syndrome) requiring blood transfusions, and complicated by HCV-related hepatitis (anti-HCV antibodies, HCV-RNA 1257491 IU/ml, genotype 1b). Previous therapy for ITP, based on prednisone, intravenous immunoglobulin (IVIg) and azathioprine had been ineffective. In 2006, she underwent splenectomy, and achieved a stable complete remission (CR), maintained with a low daily dose of prednisone (2.5 mg). …