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Published in: Journal of Nuclear Cardiology 4/2020

01-08-2020 | Pantoprazole | LETTER TO THE EDITOR

Duration of proton pump inhibitor abstinence before MPI

Authors: Ashwani Sood, DNB, Bhagwant Rai Mittal, MD, DNB, Harpreet Singh, MD

Published in: Journal of Nuclear Cardiology | Issue 4/2020

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Excerpt

We would like to express our appreciation to Lee et al. for showing great interest and critically analyzing the study we had published1. They have raised valid concerns regarding the duration of stoppage of Proton Pump Inhibitors (PPI). As they have pointed out from the study by Shin et al2, various PPI agents such as omeprazole, lansoprazole, and pantoprazole showed different times for the recovery of gastric acid secretion following stoppage of the drug. Pantoprazole had the longest duration at 45.9 hours. This would mean that the various drugs would have to be stopped for varying time durations to have the desired effect as suggested by Lee et al. …
Literature
2.
go back to reference Shin JM, Sachs G (2002) Restoration of acid secretion following treatment with proton pump inhibitors. Gastroenterology 123:1588-1597CrossRef Shin JM, Sachs G (2002) Restoration of acid secretion following treatment with proton pump inhibitors. Gastroenterology 123:1588-1597CrossRef
3.
go back to reference Katashima M, Yamamoto K, Tokuma Y et al (1998) Comparative pharmacokinetic/ pharmacodynamic analysis of proton pump inhibitors omeprazole, lansoprazole and pantoprazole in humans. Eur J Drug Metab Pharmacokinet 23:19-26CrossRef Katashima M, Yamamoto K, Tokuma Y et al (1998) Comparative pharmacokinetic/ pharmacodynamic analysis of proton pump inhibitors omeprazole, lansoprazole and pantoprazole in humans. Eur J Drug Metab Pharmacokinet 23:19-26CrossRef
Metadata
Title
Duration of proton pump inhibitor abstinence before MPI
Authors
Ashwani Sood, DNB
Bhagwant Rai Mittal, MD, DNB
Harpreet Singh, MD
Publication date
01-08-2020
Publisher
Springer International Publishing
Published in
Journal of Nuclear Cardiology / Issue 4/2020
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI
https://doi.org/10.1007/s12350-020-02193-2

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