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Current Treatment Options in Gastroenterology

26-04-2024 | Pancreatic Cyst

Pancreatic Cyst Fluid Assessment: Updates in Genetic Analysis and Risk for Progression

Authors: Muaz Aijazi, MD, Rohit Das, MD

Published in: Current Treatment Options in Gastroenterology

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Abstract

Purpose of Review

Given some pancreatic cysts require surveillance due to established malignant potential, efforts are being made to develop precise methods of early detection of advanced pancreatic neoplasia. This review focuses on genetic analysis of pancreatic cyst fluid for early detection of pancreatic cysts at high risk for neoplastic progression.

Recent Findings

Expanded, targeted next generation sequencing pathways, such as PancreaSeq, are highly sensitive and specific not just for cyst type, but also prognosticating progression to advanced neoplasia. Currently published guidelines aiding in management of pancreatic cyst surveillance have been shown to have inferior diagnostic performance when compared to algorithms involving next-generation sequencing.

Summary

Recent developments in novel next-generation sequencing pathways involving DNA/RNA based assays have increasingly allowed practitioners highly sensitive and specific modalities for early detection of advanced pancreatic neoplasia.
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Metadata
Title
Pancreatic Cyst Fluid Assessment: Updates in Genetic Analysis and Risk for Progression
Authors
Muaz Aijazi, MD
Rohit Das, MD
Publication date
26-04-2024
Publisher
Springer US
Published in
Current Treatment Options in Gastroenterology
Print ISSN: 1092-8472
Electronic ISSN: 1534-309X
DOI
https://doi.org/10.1007/s11938-024-00446-4
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

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Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

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Developed by: Springer Medicine
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