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Published in: The journal of nutrition, health & aging 6/2019

01-06-2019 | Nutrition

How Much Intake of Sodium Is Good for Frailty? : The Korean Frailty and Aging Cohort Study (KFACS)

Authors: S. Kim, M. Kim, J. Min, J. Yoo, M. Kim, J. Kang, Chang Won Won

Published in: The journal of nutrition, health & aging | Issue 6/2019

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Abstract

Objective

The aim of this study was to determine how sodium intake can affect frailty, but not anorexia, in community-dwelling older adults in Korea.

Design

This was a cross-sectional study.

Setting

The study used data from the Korean Frailty and Aging Cohort Survey (KFACS), a multi-center longitudinal study addressing 10 centers across urban, rural, and suburban communities in Korea, between 2016 and 2017.

Participants

A total of 954 older adults who underwent both 24-hour dietary recall assessment and physical function test during the first-year baseline investigation of the KFACS.

Measurements

Frailty was determined according to the Fried frailty index (FFI).

Results

Of the 954 participants, 461 (48.3%) were male and the mean age was 76.3 years old. The average daily sodium intake was 3857 mg. The frailty prevalence in first to third quartiles was 21.8%, 7.5%, and 5.4%, respectively, and increased in the fourth quartile of sodium intake to 8.9%. Using the second quartile of sodium intake (2504–3575 mg) as reference, the odds ratios of frailty were 1.64 (95% confidence interval: 0.84–3.22), 1.33 (0.57–3.06), and 4.00 (1.72–9.27) for the first (<2504 mg), third (3575–4873 mg), and fourth (≥4873 mg) quartiles, respectively, in a multivariate-adjusted analysis.

Conclusion

Low sodium intake (<2504 mg) is related to frailty in older people, but it seems to be a less important factor than other nutritional factors. The prevalence of frailty did not increase up to a daily sodium intake of 3575 mg, but it increased upon a daily sodium intake higher than 3575 mg.
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Literature
1.
go back to reference Statistics Korea. Korea Statistical Information System (KOSIS). 2013;2014:. Statistics Korea. Korea Statistical Information System (KOSIS). 2013;2014:.
2.
go back to reference Wan He, Daniel Goodkind, and Paul Kowal. International Population Reports, An Aging World: 2015, U S Census Bureau 2016;P95/16-1 Wan He, Daniel Goodkind, and Paul Kowal. International Population Reports, An Aging World: 2015, U S Census Bureau 2016;P95/16-1
3.
go back to reference Fried LP, Ferrucci L, Darer J, Williamson JD, Anderson G. Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care. J Gerontol A Biol Sci Med Sci 2004;59:255–63CrossRefPubMed Fried LP, Ferrucci L, Darer J, Williamson JD, Anderson G. Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care. J Gerontol A Biol Sci Med Sci 2004;59:255–63CrossRefPubMed
4.
go back to reference Hardy SE, Dubin JA, Holford TR, Gill TM. Transitions between states of disability and independence among older persons. Am J Epidemiol 2005;161:575–84.CrossRefPubMed Hardy SE, Dubin JA, Holford TR, Gill TM. Transitions between states of disability and independence among older persons. Am J Epidemiol 2005;161:575–84.CrossRefPubMed
5.
go back to reference Kobayashi S, Suga H, Sasaki S. Diet with a combination of high protein and high total antioxidant capacity is strongly associated with low prevalence of frailty among old Japanese women: a multicenter cross-sectional study. Nutr J. 2017;16(1):29.CrossRefPubMedPubMedCentral Kobayashi S, Suga H, Sasaki S. Diet with a combination of high protein and high total antioxidant capacity is strongly associated with low prevalence of frailty among old Japanese women: a multicenter cross-sectional study. Nutr J. 2017;16(1):29.CrossRefPubMedPubMedCentral
7.
go back to reference Fried LP. “Interventions for human frailty: physical activity as a model.” Cold Spring Harbor perspectives in medicine (2016): a025916. Fried LP. “Interventions for human frailty: physical activity as a model.” Cold Spring Harbor perspectives in medicine (2016): a025916.
8.
go back to reference Morley JE. Pathophysiology of the anorexia of aging. Curr Opin Clin Nutr Metab Care 2013;16;1:27–32.CrossRefPubMed Morley JE. Pathophysiology of the anorexia of aging. Curr Opin Clin Nutr Metab Care 2013;16;1:27–32.CrossRefPubMed
9.
go back to reference Martone AM, Onder G, Vetrano DL et al. Anorexia of aging: a modifiable risk factor for frailty. Nutrition 2013;5;10:4126–33. Martone AM, Onder G, Vetrano DL et al. Anorexia of aging: a modifiable risk factor for frailty. Nutrition 2013;5;10:4126–33.
10.
11.
go back to reference Strazzullo P, D’Elia L, Kandala NB, Cappuccio FP. Salt intake, stroke, and cardiovascular disease:meta-analysis of prospective studies. BMJ. 2009; 339:b4567. [PubMed: 19934192]CrossRefPubMedPubMedCentral Strazzullo P, D’Elia L, Kandala NB, Cappuccio FP. Salt intake, stroke, and cardiovascular disease:meta-analysis of prospective studies. BMJ. 2009; 339:b4567. [PubMed: 19934192]CrossRefPubMedPubMedCentral
12.
go back to reference Koo S, Kim Y, Kim MK, Yoon JS, Park K. Nutrient intake, lifestyle factors and prevalent hypertension in Korean adults: results from 2007–2008 Korean National Health and Nutrition Examination Survey. Korean J Community Nutr 2012;17: 329–40.CrossRef Koo S, Kim Y, Kim MK, Yoon JS, Park K. Nutrient intake, lifestyle factors and prevalent hypertension in Korean adults: results from 2007–2008 Korean National Health and Nutrition Examination Survey. Korean J Community Nutr 2012;17: 329–40.CrossRef
13.
go back to reference Nan HM, Park JW, Song YJ, Yun HY, Park JS, Hyun T, et al. Kimchi and soybean pastes are risk factors of gastric cancer. World J Gastroenterol 2005;11:3175–81.CrossRefPubMedPubMedCentral Nan HM, Park JW, Song YJ, Yun HY, Park JS, Hyun T, et al. Kimchi and soybean pastes are risk factors of gastric cancer. World J Gastroenterol 2005;11:3175–81.CrossRefPubMedPubMedCentral
14.
go back to reference Tak, YJ, et al. “Excessive Sodium Intake and Related Factors According to Energy Intakes Among Korean Elderly: A Nationwide Cross-Sectional Study.” Journal of the Korean Geriatrics Society 18.4 (2014): 185–198.CrossRef Tak, YJ, et al. “Excessive Sodium Intake and Related Factors According to Energy Intakes Among Korean Elderly: A Nationwide Cross-Sectional Study.” Journal of the Korean Geriatrics Society 18.4 (2014): 185–198.CrossRef
17.
go back to reference Appel LJ, Espeland MA, Easter L, Wilson AC, Folmar S, Lacy CR. Effects of reduced sodium intake on hypertension control in older individuals: results from the Trial of Nonpharmacologic Interventions in the Elderly (TONE). Arch Intern Med 2001;161:685–93CrossRefPubMed Appel LJ, Espeland MA, Easter L, Wilson AC, Folmar S, Lacy CR. Effects of reduced sodium intake on hypertension control in older individuals: results from the Trial of Nonpharmacologic Interventions in the Elderly (TONE). Arch Intern Med 2001;161:685–93CrossRefPubMed
18.
go back to reference Morley, John E. “Why do physicians fail to recognize and treat malnutrition in older persons?.” Journal of the American Geriatrics Society 39.11 1991; 1139–1140.CrossRef Morley, John E. “Why do physicians fail to recognize and treat malnutrition in older persons?.” Journal of the American Geriatrics Society 39.11 1991; 1139–1140.CrossRef
19.
go back to reference Won CW, Lee Y, Choi J, Kim KW, Park Y, Park H, Oh I, Ga H, Kim YS, Jang HC. Starting construction of frailty cohort for elderly and intervention study. Annals of Geriatric Medicine and Research 2016; 20: 114–7.CrossRef Won CW, Lee Y, Choi J, Kim KW, Park Y, Park H, Oh I, Ga H, Kim YS, Jang HC. Starting construction of frailty cohort for elderly and intervention study. Annals of Geriatric Medicine and Research 2016; 20: 114–7.CrossRef
20.
go back to reference Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 2001;56: M146–56.CrossRefPubMed Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 2001;56: M146–56.CrossRefPubMed
21.
go back to reference Chen LK, Liu LK, Woo J, Assantachai P, Auyeung TW, Bahyah KS, et al. Sarcopenia in asia: consensus report of the asian working group for sarcopenia. J Am Med Dir Assoc 2014;15:95–101.CrossRefPubMed Chen LK, Liu LK, Woo J, Assantachai P, Auyeung TW, Bahyah KS, et al. Sarcopenia in asia: consensus report of the asian working group for sarcopenia. J Am Med Dir Assoc 2014;15:95–101.CrossRefPubMed
22.
go back to reference Orme J, Reis J, Herz E. Factorial and discriminate validity of the Center for Epidemiological Studies depression (CES-D) scale. J Clin Psychol. 1986;42:28–33.CrossRefPubMed Orme J, Reis J, Herz E. Factorial and discriminate validity of the Center for Epidemiological Studies depression (CES-D) scale. J Clin Psychol. 1986;42:28–33.CrossRefPubMed
23.
go back to reference Son J, Kim S, Won C, Choi H, Kim B, Park M. Physical frailty predicts medical expenses in community-dwelling, elderly patients: three-year prospective findings from living profiles of older people surveys in Korea. European Geriatric Medicine. 2015;6(5):412–6CrossRef Son J, Kim S, Won C, Choi H, Kim B, Park M. Physical frailty predicts medical expenses in community-dwelling, elderly patients: three-year prospective findings from living profiles of older people surveys in Korea. European Geriatric Medicine. 2015;6(5):412–6CrossRef
24.
go back to reference Kim SY, Kang MS, Kim SN, Kim JB, Cho YS, Park HJ, Kim JH. tFood composition tables and national information network for food nutrition in Korea. Food Sci Ind 201;44:2–20 Kim SY, Kang MS, Kim SN, Kim JB, Cho YS, Park HJ, Kim JH. tFood composition tables and national information network for food nutrition in Korea. Food Sci Ind 201;44:2–20
25.
go back to reference MacKinnon, David P., Jennifer L. Krull, and Chondra M. Lockwood. “Equivalence of the mediation, confounding and suppression effect.” Prevention science 1.4 2000;173–181CrossRef MacKinnon, David P., Jennifer L. Krull, and Chondra M. Lockwood. “Equivalence of the mediation, confounding and suppression effect.” Prevention science 1.4 2000;173–181CrossRef
26.
go back to reference Graudal NJ, Jürgens G, Baslund B, Alderman MH. Compared with usual sodium intake, low- and excessive-sodium diets are associated with increased mortality: a meta-analysis. Am J Hypertens 2014; 27(9): 8. Graudal NJ, Jürgens G, Baslund B, Alderman MH. Compared with usual sodium intake, low- and excessive-sodium diets are associated with increased mortality: a meta-analysis. Am J Hypertens 2014; 27(9): 8.
28.
go back to reference Lee HS, Duffey KJ, Popkin BM. Sodium and potassium intake patterns and trends in South Korea. J Hum Hypertens 2013; 27:298–303.CrossRefPubMed Lee HS, Duffey KJ, Popkin BM. Sodium and potassium intake patterns and trends in South Korea. J Hum Hypertens 2013; 27:298–303.CrossRefPubMed
33.
go back to reference Zhang, Yong, et al. “Elevation of Fasting Ghrelin in Healthy Human Subjects Consuming a High-Salt Diet: A Novel Mechanism of Obesity?.” Nutrients 8.6 (2016):323.CrossRef Zhang, Yong, et al. “Elevation of Fasting Ghrelin in Healthy Human Subjects Consuming a High-Salt Diet: A Novel Mechanism of Obesity?.” Nutrients 8.6 (2016):323.CrossRef
Metadata
Title
How Much Intake of Sodium Is Good for Frailty? : The Korean Frailty and Aging Cohort Study (KFACS)
Authors
S. Kim
M. Kim
J. Min
J. Yoo
M. Kim
J. Kang
Chang Won Won
Publication date
01-06-2019
Publisher
Springer Paris
Keyword
Nutrition
Published in
The journal of nutrition, health & aging / Issue 6/2019
Print ISSN: 1279-7707
Electronic ISSN: 1760-4788
DOI
https://doi.org/10.1007/s12603-019-1198-6

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