Skip to main content
Top
Published in: Journal of Nuclear Cardiology 6/2020

01-12-2020 | Neurotomy | Editorial

I-123-MIBG cardiac innervation imaging in patients with atrial fibrillation

Author: Anna Teresińska, PhD

Published in: Journal of Nuclear Cardiology | Issue 6/2020

Login to get access

Excerpt

Atrial fibrillation (AF) is a supraventricular tachyarrhythmia with uncoordinated atrial activation and consequently ineffective atrial contraction.1 AF is one of the most important health problems in developed countries, with the prevalence of approximately 3% in adults aged 20 years or older, significantly increasing with advancing age. It is associated with an increased risk of stroke (five-fold), heart failure (three-fold), and dementia (two-fold). This arrhythmia is independently associated with nearly a two-fold increased risk of all-cause mortality, especially cardiovascular mortality due to sudden death, heart failure, or stroke.1,2
Literature
1.
go back to reference January CT, Wann LS, Alpert JS, Calkins H, Cigarroa JE, Cleveland JC Jr, et al. 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol. 2014;64:e1–76.CrossRef January CT, Wann LS, Alpert JS, Calkins H, Cigarroa JE, Cleveland JC Jr, et al. 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol. 2014;64:e1–76.CrossRef
2.
go back to reference Kirchhof P, Benussi S, Kotecha D, Ahlsson A, Atar D, Casadei B, et al. 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS. Eur Heart J. 2016;37:2893–962.CrossRef Kirchhof P, Benussi S, Kotecha D, Ahlsson A, Atar D, Casadei B, et al. 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS. Eur Heart J. 2016;37:2893–962.CrossRef
3.
go back to reference Calkins H, Hindricks G, Cappato R, Kim Y-H, Saad EB, Aguinaga L, et al. 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation. Europace. 2017;20:e1–160.CrossRef Calkins H, Hindricks G, Cappato R, Kim Y-H, Saad EB, Aguinaga L, et al. 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation. Europace. 2017;20:e1–160.CrossRef
4.
go back to reference Chirumamilla A, Travin MI. Cardiac applications of 123I-mIBG imaging. Semin Nucl Med. 2011;41:374–87.CrossRef Chirumamilla A, Travin MI. Cardiac applications of 123I-mIBG imaging. Semin Nucl Med. 2011;41:374–87.CrossRef
5.
go back to reference Akutsu Y, Kaneko K, Kodama Y, Li HL, Suyama J, Shinozuka A, et al. Significance of cardiac sympathetic nervous system abnormality for predicting vascular events in patients with idiopathic paroxysmal atrial fibrillation. Eur J Nucl Med Mol Imaging. 2010;37:742–9.CrossRef Akutsu Y, Kaneko K, Kodama Y, Li HL, Suyama J, Shinozuka A, et al. Significance of cardiac sympathetic nervous system abnormality for predicting vascular events in patients with idiopathic paroxysmal atrial fibrillation. Eur J Nucl Med Mol Imaging. 2010;37:742–9.CrossRef
6.
go back to reference Akutsu Y, Kaneko K, Kodama Y, Li H-L, Suyama J, Shinozuka A, et al. Iodine-123 mIBG imaging for predicting the development of atrial fibrillation. JACC Cardiovasc Imaging. 2011;4:78–86.CrossRef Akutsu Y, Kaneko K, Kodama Y, Li H-L, Suyama J, Shinozuka A, et al. Iodine-123 mIBG imaging for predicting the development of atrial fibrillation. JACC Cardiovasc Imaging. 2011;4:78–86.CrossRef
7.
go back to reference Arimoto T, Tada H, Igarashi M, Sekiguchi Y, Sato A, Koyama T, et al. High washout rate of iodine-123-metaiodobenzylguanidine imaging predicts the outcome of catheter ablation of atrial fibrillation. J Cardiovasc Electrophysiol. 2011;22:1297–304.CrossRef Arimoto T, Tada H, Igarashi M, Sekiguchi Y, Sato A, Koyama T, et al. High washout rate of iodine-123-metaiodobenzylguanidine imaging predicts the outcome of catheter ablation of atrial fibrillation. J Cardiovasc Electrophysiol. 2011;22:1297–304.CrossRef
8.
go back to reference Wenning C, Lange PS, Schulke Ch, Vrachimis A, Monnig G, Schober O, et al. Pulmonary vein isolation in patients with paroxysmal atrial fibrillation is associated with regional cardiac sympathetic denervation. EJNMMI Res. 2013;3:81.CrossRef Wenning C, Lange PS, Schulke Ch, Vrachimis A, Monnig G, Schober O, et al. Pulmonary vein isolation in patients with paroxysmal atrial fibrillation is associated with regional cardiac sympathetic denervation. EJNMMI Res. 2013;3:81.CrossRef
9.
go back to reference Lemery R, Ben-Haim S, Wells G, Ruddy T. I-123-Metaiodobenzylguanidine imaging in patients with atrial fibrillation undergoing cardiac mapping and ablation of autonomic ganglia. Heart Rhythm. 2017;14:128–32.CrossRef Lemery R, Ben-Haim S, Wells G, Ruddy T. I-123-Metaiodobenzylguanidine imaging in patients with atrial fibrillation undergoing cardiac mapping and ablation of autonomic ganglia. Heart Rhythm. 2017;14:128–32.CrossRef
10.
go back to reference Ovadia M, Dugue KS. The Potential Utility of 123I-mIBG in Atrial Fibrillation and in the Electrophysiology Laboratory. Curr Cardiol Rep. 2012;4:200–7.CrossRef Ovadia M, Dugue KS. The Potential Utility of 123I-mIBG in Atrial Fibrillation and in the Electrophysiology Laboratory. Curr Cardiol Rep. 2012;4:200–7.CrossRef
11.
go back to reference Armour JA. Potential clinical relevance of the “little brain” on the mammalian heart. Exp Physiol. 2008;93:165–76.CrossRef Armour JA. Potential clinical relevance of the “little brain” on the mammalian heart. Exp Physiol. 2008;93:165–76.CrossRef
12.
go back to reference Teresinska A, Sliwinski M, Konieczna S, Szumilak B, Szymanska M, Debski A, et al. Changes in cardiac adrenergic nervous system after transmyocardial laser revascularisation assessed by I-123-MIBG SPECT. A preliminary report. Kardiol Pol. 2004;60:15–26.PubMed Teresinska A, Sliwinski M, Konieczna S, Szumilak B, Szymanska M, Debski A, et al. Changes in cardiac adrenergic nervous system after transmyocardial laser revascularisation assessed by I-123-MIBG SPECT. A preliminary report. Kardiol Pol. 2004;60:15–26.PubMed
13.
go back to reference Awad M, Czer LSC, Hou M, Golshani SS, Goltche M, De Robertis M, et al. Early denervation and later reinnervation of the heart following cardiac transplantation: a review. J Am Heart Assoc. 2016;5:e004070.CrossRef Awad M, Czer LSC, Hou M, Golshani SS, Goltche M, De Robertis M, et al. Early denervation and later reinnervation of the heart following cardiac transplantation: a review. J Am Heart Assoc. 2016;5:e004070.CrossRef
14.
go back to reference Katritsis DG, Pokushalov E, Romanov A, Giazitzoglou E, Siontis GCM, Po SS, et al. Autonomic denervation added to pulmonary vein isolation for paroxysmal atrial fibrillation: a randomized clinical trial. J Am Coll Cardiol. 2013;62:2318–25.CrossRef Katritsis DG, Pokushalov E, Romanov A, Giazitzoglou E, Siontis GCM, Po SS, et al. Autonomic denervation added to pulmonary vein isolation for paroxysmal atrial fibrillation: a randomized clinical trial. J Am Coll Cardiol. 2013;62:2318–25.CrossRef
15.
go back to reference Bauer A, Deisenhofer I, Schneider R, Zrenner B, Barthel P, Karch M, et al. Effects of circumferential or segmental pulmonary vein ablation for paroxysmal atrial fibrillation on cardiac autonomic function. Heart Rhythm. 2006;3:1428–35.CrossRef Bauer A, Deisenhofer I, Schneider R, Zrenner B, Barthel P, Karch M, et al. Effects of circumferential or segmental pulmonary vein ablation for paroxysmal atrial fibrillation on cardiac autonomic function. Heart Rhythm. 2006;3:1428–35.CrossRef
16.
go back to reference Stavrakis S, Po S. Ganglionated Plexi Ablation: physiology and Clinical Applications. Arrhythm Electrophysiol Rev. 2017;6:186–90.CrossRef Stavrakis S, Po S. Ganglionated Plexi Ablation: physiology and Clinical Applications. Arrhythm Electrophysiol Rev. 2017;6:186–90.CrossRef
17.
go back to reference Bellevre D, Manrique A, Legallois D, Bross S, Baavour R, Roth N, et al. First determination of the heart-to-mediastinum ratio using cardiac dual isotope (123I-MIBG/99mTc-tetrofosmin) CZT imaging in patients with heart failure: the ADRECARD study. Eur J Nucl Med Mol Imaging. 2015;42:1912–9.CrossRef Bellevre D, Manrique A, Legallois D, Bross S, Baavour R, Roth N, et al. First determination of the heart-to-mediastinum ratio using cardiac dual isotope (123I-MIBG/99mTc-tetrofosmin) CZT imaging in patients with heart failure: the ADRECARD study. Eur J Nucl Med Mol Imaging. 2015;42:1912–9.CrossRef
18.
go back to reference Gambhir SS, Berman DS, Ziffer J, Nagler M, Sandler M, Patton J, et al. A novel high-sensitivity rapid-acquisition single-photon cardiac imaging camera. J Nucl Med. 2009;50:635–43.CrossRef Gambhir SS, Berman DS, Ziffer J, Nagler M, Sandler M, Patton J, et al. A novel high-sensitivity rapid-acquisition single-photon cardiac imaging camera. J Nucl Med. 2009;50:635–43.CrossRef
19.
go back to reference Romanov A, Minin S, Breault Ch, Pokushalov E. Visualization and ablation of the autonomic nervous system corresponding to ganglionated plexi guided by D-SPECT 123ImIBG imaging in patient with paroxysmal atrial fibrillation. Clin Res Cardiol. 2017;106:76–8.CrossRef Romanov A, Minin S, Breault Ch, Pokushalov E. Visualization and ablation of the autonomic nervous system corresponding to ganglionated plexi guided by D-SPECT 123ImIBG imaging in patient with paroxysmal atrial fibrillation. Clin Res Cardiol. 2017;106:76–8.CrossRef
20.
go back to reference Stirrup J, Gregg S, Baavour R, Roth N, Breault Ch, Agostini D, et al. (2019) Hybrid solid-state SPECT/CT left atrial innervation imaging for identification of left atrial ganglionated plexi: technique and validation in patients with atrial fibrillation. J Nucl Cardiol. Stirrup J, Gregg S, Baavour R, Roth N, Breault Ch, Agostini D, et al. (2019) Hybrid solid-state SPECT/CT left atrial innervation imaging for identification of left atrial ganglionated plexi: technique and validation in patients with atrial fibrillation. J Nucl Cardiol.
21.
go back to reference Joshi NV, Vesey AT, Williams MC, Shah AS, Calvert PA, Craighead FH, et al. 18F-fluoride positron emission tomography for identification of ruptured and high-risk coronary atherosclerotic plaques: a prospective clinical trial. Lancet. 2014;383:705–13.CrossRef Joshi NV, Vesey AT, Williams MC, Shah AS, Calvert PA, Craighead FH, et al. 18F-fluoride positron emission tomography for identification of ruptured and high-risk coronary atherosclerotic plaques: a prospective clinical trial. Lancet. 2014;383:705–13.CrossRef
22.
go back to reference Werner RA, Chen X, Hirano M, Rowe SP, Lapa C, Javadi, Higuchi T. SPECT vs. PET in cardiac innervation imaging: clash of the titans. Clin Transl Imaging. 2018;6:293–303.CrossRef Werner RA, Chen X, Hirano M, Rowe SP, Lapa C, Javadi, Higuchi T. SPECT vs. PET in cardiac innervation imaging: clash of the titans. Clin Transl Imaging. 2018;6:293–303.CrossRef
Metadata
Title
I-123-MIBG cardiac innervation imaging in patients with atrial fibrillation
Author
Anna Teresińska, PhD
Publication date
01-12-2020
Publisher
Springer International Publishing
Published in
Journal of Nuclear Cardiology / Issue 6/2020
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI
https://doi.org/10.1007/s12350-019-01601-6

Other articles of this Issue 6/2020

Journal of Nuclear Cardiology 6/2020 Go to the issue