Hepatic radiotracer: Still difficult to suppress?

Excerpt

Coronary artery disease, CAD, is the leading cause of death and disability in most developed nations and of increasing prevalence in developing nations worldwide. Single-photon emission computed tomography SPECT myocardial perfusion imaging (SPECT MPI), with radiotracer 99mTc-methoxyisobutylisonitrile (MIBI), provides an accurate, safe, and clinically useful tool for the diagnosis, prognostication, and management of patients with known or suspected CAD. SPECT MPI serves as the most common imaging modality for assessment for possible coronary ischemia with approximately 15-20 million cases annually.1 Nevertheless, imaging artifacts may limit SPECT accuracy including motion artifacts, attenuation artifacts from overlying soft tissue structures such as breast, or altered myocardial tracer appearance from excessive bowel or liver tracer. …