Advances for pediatricians in 2022: allergy, anesthesiology, cardiology, dermatology, endocrinology, gastroenterology, genetics, global health, infectious diseases, metabolism, neonatology, neurology, oncology, pulmonology

1.

Ricci G, Andreozzi L, Cipriani F, Giannetti A, Gallucci M, Caffarelli C. Wheat allergy in children: a comprehensive update. Med (Kaunas). 2019;55:400. https://doi.org/10.3390/medicina55070400.CrossRef

2.

Mastrorilli C, Cardinale F, Giannetti A, Caffarelli C. Pollen-food allergy syndrome: a not so rare disease in childhood. Med (Kaunas). 2016;55:641. https://doi.org/10.3390/medicina55100641.CrossRef

3.

Berni Canani R, Caffarelli C, Calvani M, Martelli A, Carucci L, Cozzolino T, et al. Diagnostic therapeutic care pathway for pediatric food allergies and intolerances in Italy: a joint position paper by the italian society for Pediatric Gastroenterology Hepatology and Nutrition (SIGENP) and the italian society for Pediatric Allergy and Immunology (SIAIP). Ital J Pediatr. 2022;48:87. https://doi.org/10.1186/s13052-022-01277-8.CrossRefPubMedPubMedCentral

4.

Caffarelli C, Ricò S, Varini M, Povesi-Dascola C, Mastrorilli C. Skin prick test and development of tolerance in egg allergy. Pediatr Allergy Immunol. 2016;27:881–4. https://doi.org/10.1111/pai.12625.CrossRefPubMed

5.

Caffarelli C, Ricò S, Rinaldi L, Povesi Dascola C, Terzi C, Bernasconi S. Blood pressure monitoring in children undergoing food challenge: association with anaphylaxis. Ann Allergy Asthma Immunol. 2012;108:285–6. https://doi.org/10.1016/j.anai.2012.02.001.CrossRefPubMed

6.

Caffarelli C, Dondi A, Povesi Dascola C, Ricci G. Skin prick test to foods in childhood atopic eczema: pros and cons. Ital J Pediatr. 2013;39:48. https://doi.org/10.1186/1824-7288-39-48.CrossRefPubMedPubMedCentral

7.

Galli E, Fortina AB, Ricci G, Maiello N, Neri I, Baldo E, et al. Narrative review on the management of moderate-severe atopic dermatitis in pediatric age of the italian society of Pediatric Allergology and Immunology (SIAIP), of the italian society of Pediatric Dermatology (SIDerP) and of the italian society of pediatrics (SIP). Ital J Pediatr. 2022;48:95. https://doi.org/10.1186/s13052-022-01278-7.CrossRefPubMedPubMedCentral

8.

Di Rienzo V, Cadario G, Grieco T, Galluccio AG, Caffarelli C, Liotta G, et al. Sublingual immunotherapy in mite-sensitized children with atopic dermatitis: a randomized, open, parallel-group study. Ann Allergy Asthma Immunol. 2014;113:671–673e1. https://doi.org/10.1016/j.anai.2014.09.009.CrossRefPubMed

9.

Caffarelli C, Dascola CP, Peroni D, Ricò S, Stringari G, Varini M, et al. Airway acidification in childhood asthma exacerbations. Allergy Asthma Proc. 2014;35:51–6. https://doi.org/10.2500/aap.2014.35.3740.CrossRefPubMed

10.

Caffarelli C, Calcinai E, Rinaldi L, Povesi Dascola C, Terracciano L, Corradi M. Hydrogen peroxide in exhaled breath condensate in asthmatic children during acute exacerbation and after treatment. Respiration. 2012;84:291–8. https://doi.org/10.1159/000341969.CrossRefPubMed

11.

Zinelli C, Caffarelli C, Strid J, Jaffe A, Atherton DJ. Measurement of nitric oxide and 8-isoprostane in exhaled breath of children with atopic eczema. Clin Exp Dermatol. 2009;34:607–12. https://doi.org/10.1111/j.1365-2230.2008.03142.x.CrossRefPubMed

12.

Riscassi S, Corradi M, Andreoli R, Maccari C, Mercolini F, Pescollderungg L, et al. Nitric oxide products and aldehydes in exhaled breath condensate in children with asthma. Clin Exp Allergy. 2022;52:561–4. https://doi.org/10.1111/cea.14066.CrossRefPubMed

13.

Manna A, Caffarelli C, Varini M, Povesi Dascola C, Montella S, Maglione M, et al. Clinical application of exhaled nitric oxide measurement in pediatric lung diseases. Ital J Pediatr. 2012;38:74. https://doi.org/10.1186/1824-7288-38-74.CrossRefPubMedPubMedCentral

14.

McCrossan P, Mallon O, Shields MD, Russell C, Kennedy L, O’Donoghue D. How we teach children with asthma to use their inhaler: a scoping review. Ital J Pediatr. 2022;48:52. https://doi.org/10.1186/s13052-022-01237-2.CrossRefPubMedPubMedCentral

15.

Mastrorilli C, Pecoraro L, Arasi S, Barni S, Caminiti L, Castagnoli R, et al. Rare allergic Diseases Commission of the italian society of Pediatric Allergy and Immunology. Pediatric hypersensitivity pneumonitis: literature update and proposal of a diagnostic algorithm. Ital J Pediatr. 2022;48:51. https://doi.org/10.1186/s13052-022-01239-0.CrossRefPubMedPubMedCentral

16.

Wawszczak M, Bielecka T, Szczukocki M. Hypersensitivity pneumonitis in children. Ann Agric Environ Med. 2021;28:214–9. https://doi.org/10.26444/aaem/118830.CrossRefPubMed

17.

Bush A, Cunningham S, de Blic J, Barbato A, Clement A, Epaud R, et al. European protocols for the diagnosis and initial treatment of interstitial lung disease in children. Thorax. 2015;70:1078–84. https://doi.org/10.1136/thoraxjnl-2015-207349.CrossRefPubMed

18.

Toyotome T, Satoh M, Yahiro M, Watanabe A, Nomura F, Kamei K. Glucoamylase is a major allergen of Schizophyllum commune. Clin Exp Allergy. 2014;44:450–7. https://doi.org/10.1111/cea.12260.CrossRefPubMed

19.

Cossovel F, Trombetta A, Ramondo A, Riccio G, Ronfani L, Saccari A, et al. Intranasal dexmedetomidine and intranasal ketamine association allows shorter induction time for pediatric sedation compared to intranasal dexmedetomidine and oral midazolam. Ital J Pediatr. 2022;48:5. https://doi.org/10.1186/s13052-021-01196-0.CrossRefPubMedPubMedCentral

20.

Li BL, Luo H, Huang JX, Zhang HH, Paquin JR, Yuen VM, et al. Using intranasal dexmedetomidine with buccal midazolam for magnetic resonance imaging sedation in children: a single-arm prospective interventional study. Front Pediatr. 2022;10:889369. https://doi.org/10.3389/fped.2022.889369.CrossRefPubMedPubMedCentral

21.

Gu H, Miao L, Bai J, Lu G, Lei Q, Yang L, et al. Combined use of intranasal dexmedetomidine and an oral novel formulation of Midazolam for sedation of young children during brain MRI examination: a prospective, single-center, randomized controlled trial. BMC Anesthesiol. 2022;22:357. https://doi.org/10.1186/s12871-022-01897-x.CrossRefPubMedPubMedCentral

22.

Cui Y, Gong T, Mu Q, Wu Q, Kang L, Chen Q et al. Predictors of pediatric sedation failure with initial dose of intranasal dexmedetomidine and oral midazolam. Pediatr Res 2023 Jul 28. https://doi.org/10.1038/s41390-023-02758-0. Online ahead of print.

23.

Candelino M, Tagi VM, Chiarelli F. Cardiovascular risk in children: a burden for future generations. Ital J Pediatr. 2022;48:57. https://doi.org/10.1186/s13052-022-01250-5.CrossRefPubMedPubMedCentral

24.

Schipper HS, de Ferranti S. Atherosclerotic cardiovascular risk as an emerging priority in pediatrics. Pediatrics. 2022;150:e2022057956. https://doi.org/10.1542/peds.2022-057956.CrossRefPubMed

25.

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26.

Pool LR, Aguayo L, Brzezinski M, Perak AM, Davis MM, Greenland P, et al. Childhood risk factors and adulthood cardiovascular disease: a systematic review. J Pediatr. 2021;232:118–126e23. https://doi.org/10.1016/j.jpeds.2021.01.053.CrossRefPubMed

27.

Pensabene M, Di Pace MR, Baldanza F, Grasso F, Patti M, Sergio M, et al. Quality of life improving after propranolol treatment in patients with infantile hemangiomas. Ital J Pediatr. 2022;48:140. https://doi.org/10.1186/s13052-022-01334-2.CrossRefPubMedPubMedCentral

28.

Pahl KS, McLean TW. Infantile hemangioma: a current review. J Pediatr Hematol Oncol. 2022;44:31–9. https://doi.org/10.1097/MPH.0000000000002384.CrossRefPubMed

29.

Lorusso B, Cerasoli G, Falco A, Frati C, Graiani G, Madeddu D, et al. Β-blockers activate autophagy on infantile hemangioma-derived endothelial cells in vitro. Vascul Pharmacol. 2022;146:107110. https://doi.org/10.1016/j.vph.2022.107110.CrossRefPubMed

30.

Léauté-Labrèze C, Frieden I, Delarue A. Early initiation of treatment with oral propranolol for infantile hemangioma improves success rate. Pediatr Dermatol. 2023;40:261–4. https://doi.org/10.1111/pde.15198.CrossRefPubMed

31.

Retrosi C, Diociaiuti A, De Ranieri C, Corbeddu M, Carnevale C, Giancristoforo S, et al. Multidisciplinary care for patients with epidermolysis bullosa from birth to adolescence: experience of one italian reference center. Ital J Pediatr. 2022;48:58. https://doi.org/10.1186/s13052-022-01252-3.CrossRefPubMedPubMedCentral

32.

Mauritz P, Jonkman MF, Visser SS, Finkenauer C, Duipmans JC, Hagedoorn M. Impact of painful wound care in epidermolysis bullosa during childhood: an interview study with adult patients and parents. Acta Derm Venereol. 2019;99:783–8. https://doi.org/10.2340/00015555-3179.CrossRefPubMed

33.

Fine J-D, Johnson LB, Weiner M, Suchindran C. Cause-specific risks of childhood death in inherited epidermolysis bullosa. J Pediatr. 2008;152:276–80. https://doi.org/10.1016/j.jpeds.2007.06.039.CrossRefPubMed

34.

Montaudié H, Chiaverini C, Sbidian E, Charlesworth A, Lacour JP. Inherited epidermolysis bullosa and squamous cell carcinoma: a systematic review of 117 cases. Orphanet J Rare Dis. 2016;11:117. https://doi.org/10.1186/s13023-016-0489-9.CrossRefPubMedPubMedCentral

35.

Vahlquist A, Fischer J, Törmä H. Inherited nonsyndromic ichthyoses: an update on pathophysiology, diagnosis and treatment. Am J Clin Dermatol. 2018;19:51–66. https://doi.org/10.1007/s40257-017-0313-x.CrossRefPubMed

36.

Serra G, Memo L, Cavicchioli P, Cutrone M, Giuffrè M, La Torre ML, et al. Novel mutations of the ABCA12, KRT1 and ST14 genes in three unrelated newborns showing congenital ichthyosis. Ital J Pediatr. 2022;48:145. https://doi.org/10.1186/s13052-022-01336-0.CrossRefPubMedPubMedCentral

37.

Akiyama M. ABCA12 mutations and autosomal recessive congenital ichthyosis: a review of genotype/phenotype correlations and of pathogeneticoncepts. Hum Mutat. 2010;31:1090–6. https://doi.org/10.1002/humu.21326.CrossRefPubMed

38.

Serra G, Memo L, Coscia A, Giuffré M, Iuculano A, Lanna M, et al. Recommendations for neonatologists and pediatricians working in first level birthing centers on the first communication of genetic disease and malformation syndrome diagnosis: consensus issued by 6 italian scientific societies and 4 parents’ associations. Ital J Pediatr. 2021;47:94. https://doi.org/10.1186/s13052-021-01044-1.CrossRefPubMedPubMedCentral

39.

Nicolucci A, Maffeis C. The adolescent with obesity: what perspectives for treatment? Ital J Pediatr. 2022;48:9. https://doi.org/10.1186/s13052-022-01205-w.CrossRefPubMedPubMedCentral

40.

Kelly AS. Current and future pharmacotherapies for obesity in children and adolescents. Nat Rev Endocrinol. 2023;19:534–41. https://doi.org/10.1038/s41574-023-00858-9.CrossRefPubMed

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Wu Z, Gao Z, Qiao Y, Chen F, Guan B, Wu L, et al. Long-term results of bariatric surgery in adolescents with at least 5 years of follow-up: a systematic review and meta-analysis. Obes Surg. 2023;33:1730–45. https://doi.org/10.1007/s11695-023-06593-4.CrossRefPubMed

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43.

Gaeta F, Conti V, Pepe A, Vajro P, Filippelli A, Mandato C. Drug dosing in children with obesity: a narrative updated review. Ital J Pediatr. 2022;48:168. https://doi.org/10.1186/s13052-022-01361-z.CrossRefPubMedPubMedCentral

44.

Bradley SJ, Nelson JD, Barnett E, Cantey JB, Kimberlin DW, Palumbo PE, et al. Nelson’s Pediatric Antimicrobial Therapy. Am Acad Pediatr. 2021. https://doi.org/10.1542/9781610024457ISBN. 27th ed.CrossRef

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Garner MP, Onuoha CP, Fenn NE 3rd. Low-molecular-weight heparin and Fondaparinux use in pediatric patients with obesity. Ann Pharmacother. 2021;55:666–76. https://doi.org/10.1177/1060028020955029.CrossRefPubMed

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Sadat-Ali M, AlTabash KW, Al-Turki HA, AlMousa SA, AlSayed HN. Time out: should vitamin D dosing be based on patient’s body mass index (BMI): a prospective controlled study. J Nutr Sci. 2021;10:e106. https://doi.org/10.1017/jns.2021.100.CrossRefPubMedPubMedCentral

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Ferrari V, Stefanucci S, Ciofi D, Stagi S. Analysis of the timing of puberty in a recent cohort of italian girls: evidence for earlier onset compared to previous studies. J Pediatr Adolesc Gynecol. 2022;35:23–9. https://doi.org/10.1016/j.jpag.2021.06.007.CrossRefPubMed

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Ferrari V, Stefanucci S, Ferrari M, Ciofi D, Stagi S, on the behalf of the Tuscany Menarche Study Group. Retrospective longitudinal analysis of the effects of postnatal weight gain on the timing and tempo of puberty and menarche in a cohort of italian girls. Ital J Pediatr. 2022;48:20. https://doi.org/10.1186/s13052-022-01222-9.CrossRefPubMedPubMedCentral

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Keynote webinar | Spotlight on medication adherence

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Keynote webinar | Spotlight on medication adherence

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