Skip to main content
Top
Published in: Italian Journal of Pediatrics 1/2013

Open Access 01-12-2013 | Review

Skin prick test to foods in childhood atopic eczema: pros and cons

Authors: Carlo Caffarelli, Arianna Dondi, Carlotta Povesi Dascola, Giampaolo Ricci

Published in: Italian Journal of Pediatrics | Issue 1/2013

Login to get access

Abstract

Skin prick tests are the first investigation in allergy diagnostics and their use is described in all the guidelines on atopic eczema. However, the clinical usefulness of skin prick tests is the subject of great debate. On the one hand, skin prick tests allow the identification both of individuals at risk for food allergy and of the allergen inducing the eczematous flare. On the other hand, when performed by a non-specific specialist, positive skin prick tests to foods may wrongly lead to prolonged elimination diets, which may induce nutritional deficiencies and perhaps loss of tolerance to the avoided foods. Furthermore, skin prick tests increase health costs. A consensus on this topic has not yet been reached. Considering the diversity of clinical stages in which it occurs, atopic eczema presentation should be the starting point to determine whether or not skin prick tests should be carried out.
Literature
1.
go back to reference Darsow U, Wollenberg A, Simon D, Taïeb A, Werfel T, Oranje A, Gelmetti C, Svensson A, Deleuran M, Calza AM, Giusti F, Lübbe J, Seidenari S, Ring J, European Task Force on Atopic Dermatitis/EADV Eczema Task Force: ETFAD/EADV eczema task force 2009 position paper on diagnosis and treatment of atopic dermatitis. J Eur Acad Dermatol Venereol. 2010, 24: 317-328. 10.1111/j.1468-3083.2009.03415.x.CrossRefPubMed Darsow U, Wollenberg A, Simon D, Taïeb A, Werfel T, Oranje A, Gelmetti C, Svensson A, Deleuran M, Calza AM, Giusti F, Lübbe J, Seidenari S, Ring J, European Task Force on Atopic Dermatitis/EADV Eczema Task Force: ETFAD/EADV eczema task force 2009 position paper on diagnosis and treatment of atopic dermatitis. J Eur Acad Dermatol Venereol. 2010, 24: 317-328. 10.1111/j.1468-3083.2009.03415.x.CrossRefPubMed
2.
go back to reference Rancé F, Boguniewicz M, Lau S: New visions for atopic eczema: an iPAC summary and future trends. Pediatr Allergy Immunol. 2008, 19 (Suppl 19): 17-25.CrossRefPubMed Rancé F, Boguniewicz M, Lau S: New visions for atopic eczema: an iPAC summary and future trends. Pediatr Allergy Immunol. 2008, 19 (Suppl 19): 17-25.CrossRefPubMed
3.
go back to reference Greenhawt M: The role of food allergy in atopic dermatitis. Allergy Asthma Proc. 2010, 31: 392-397. 10.2500/aap.2010.31.3393.CrossRefPubMed Greenhawt M: The role of food allergy in atopic dermatitis. Allergy Asthma Proc. 2010, 31: 392-397. 10.2500/aap.2010.31.3393.CrossRefPubMed
4.
go back to reference de Bruin Weller MS, Knulst AC, Meijer Y, Bruijnzeel-Koomen CAFM, Pasmans SGM: Evaluation of the child with atopic dermatitis. Clin Exp Allergy. 2012, 42: 352-362. 10.1111/j.1365-2222.2011.03899.x.CrossRefPubMed de Bruin Weller MS, Knulst AC, Meijer Y, Bruijnzeel-Koomen CAFM, Pasmans SGM: Evaluation of the child with atopic dermatitis. Clin Exp Allergy. 2012, 42: 352-362. 10.1111/j.1365-2222.2011.03899.x.CrossRefPubMed
6.
go back to reference Caffarelli C, Coscia A, Ridolo E, Povesi Dascola C, Gelmetti C, Raggi V, Volta E, Vanelli M, Vanelli M: Parents’ estimate of food allergy prevalence and management in Italian school-aged children. Pediatr Int. 2011, 53: 505-510. 10.1111/j.1442-200X.2010.03294.x.CrossRefPubMed Caffarelli C, Coscia A, Ridolo E, Povesi Dascola C, Gelmetti C, Raggi V, Volta E, Vanelli M, Vanelli M: Parents’ estimate of food allergy prevalence and management in Italian school-aged children. Pediatr Int. 2011, 53: 505-510. 10.1111/j.1442-200X.2010.03294.x.CrossRefPubMed
7.
go back to reference Caffarelli C, Baldi F, Bendandi B, Calzone L, Marani M, Pasquinelli P, on behalf of EWGPAG: Cow’s milk protein allergy in children: a practical guide. Ital J Pediatr. 2010, 36: 5-10.1186/1824-7288-36-5.PubMedCentralCrossRefPubMed Caffarelli C, Baldi F, Bendandi B, Calzone L, Marani M, Pasquinelli P, on behalf of EWGPAG: Cow’s milk protein allergy in children: a practical guide. Ital J Pediatr. 2010, 36: 5-10.1186/1824-7288-36-5.PubMedCentralCrossRefPubMed
8.
go back to reference Sampson HA, Albergo R: Comparison of results of skin tests, RAST and double-blind, placebo-controlled food challanges in children with atopic dermatitis. J Allergy Clin Immunol. 1984, 74: 26-33. 10.1016/0091-6749(84)90083-6.CrossRefPubMed Sampson HA, Albergo R: Comparison of results of skin tests, RAST and double-blind, placebo-controlled food challanges in children with atopic dermatitis. J Allergy Clin Immunol. 1984, 74: 26-33. 10.1016/0091-6749(84)90083-6.CrossRefPubMed
9.
go back to reference Lipozenčic J, Wolf R: The diagnostic value of atopy patch testing and prick testing in atopic dermatitis: facts and controversies. Clinics in Dermatology. 2010, 28: 38-44. 10.1016/j.clindermatol.2009.03.008.CrossRefPubMed Lipozenčic J, Wolf R: The diagnostic value of atopy patch testing and prick testing in atopic dermatitis: facts and controversies. Clinics in Dermatology. 2010, 28: 38-44. 10.1016/j.clindermatol.2009.03.008.CrossRefPubMed
10.
go back to reference Sporik R, Hill DG, Hosking CS: Specificity of allergen skin testing in predicting positive open food challenges to milk, egg and peanut in children. Clin Exp Allergy. 2000, 30: 1540-1546.CrossRefPubMed Sporik R, Hill DG, Hosking CS: Specificity of allergen skin testing in predicting positive open food challenges to milk, egg and peanut in children. Clin Exp Allergy. 2000, 30: 1540-1546.CrossRefPubMed
11.
go back to reference Mehl A, Rolinck-Werninghaus C, Staden U: The atopy patch test in the diagnostic workup of suspected food-related symptoms in children. J Allergy Clin Immunol. 2006, 118: 923-929. 10.1016/j.jaci.2006.07.003.CrossRefPubMed Mehl A, Rolinck-Werninghaus C, Staden U: The atopy patch test in the diagnostic workup of suspected food-related symptoms in children. J Allergy Clin Immunol. 2006, 118: 923-929. 10.1016/j.jaci.2006.07.003.CrossRefPubMed
12.
go back to reference Breuer K, Hetatizadeh A, Wulf A, Baumann U, Constien A, Tetau D: Late eczematous reactions to food in children with atopic dermatitis. Clin Exp Allergy. 2004, 34: 817-824. 10.1111/j.1365-2222.2004.1953.x.CrossRefPubMed Breuer K, Hetatizadeh A, Wulf A, Baumann U, Constien A, Tetau D: Late eczematous reactions to food in children with atopic dermatitis. Clin Exp Allergy. 2004, 34: 817-824. 10.1111/j.1365-2222.2004.1953.x.CrossRefPubMed
13.
go back to reference Burks AW, Mallory SB, Williams LW, Shirrell MA: Atopic dermatitis: clinical relevance of food hypersensitivity reactions. J Pediatr. 1988, 113: 447-45. 10.1016/S0022-3476(88)80626-7.CrossRefPubMed Burks AW, Mallory SB, Williams LW, Shirrell MA: Atopic dermatitis: clinical relevance of food hypersensitivity reactions. J Pediatr. 1988, 113: 447-45. 10.1016/S0022-3476(88)80626-7.CrossRefPubMed
14.
go back to reference Lever R, MacDonald C, Waugh P, Aitchison T: Randomised controlled trial of advice on an egg exclusion diet in young children with atopic eczema and sensitivity to eggs. Pediatr Allergy Immunol. 1998, 9: 13-19. 10.1111/j.1399-3038.1998.tb00294.x.CrossRefPubMed Lever R, MacDonald C, Waugh P, Aitchison T: Randomised controlled trial of advice on an egg exclusion diet in young children with atopic eczema and sensitivity to eggs. Pediatr Allergy Immunol. 1998, 9: 13-19. 10.1111/j.1399-3038.1998.tb00294.x.CrossRefPubMed
15.
go back to reference Breuer K, Wulf A, Constien A, Tetau D, Kapp A, Werfel T: Birch pollen-related food as a provocation factor of allergic symptoms in children with atopic eczema/dermatitis syndrome. Allergy. 2004, 59: 988-994. 10.1111/j.1398-9995.2004.00493.x.CrossRefPubMed Breuer K, Wulf A, Constien A, Tetau D, Kapp A, Werfel T: Birch pollen-related food as a provocation factor of allergic symptoms in children with atopic eczema/dermatitis syndrome. Allergy. 2004, 59: 988-994. 10.1111/j.1398-9995.2004.00493.x.CrossRefPubMed
16.
go back to reference Reekers R, Busch M, Whittmann M, Kapp A, Werfel T: Birch pollen-related foods trigger atopic dermatitis in patients with specific cutaneous T-cell responses to birch pollen antigens. J Allergy Clin Immunol. 1999, 104: 466-472. 10.1016/S0091-6749(99)70395-7.CrossRefPubMed Reekers R, Busch M, Whittmann M, Kapp A, Werfel T: Birch pollen-related foods trigger atopic dermatitis in patients with specific cutaneous T-cell responses to birch pollen antigens. J Allergy Clin Immunol. 1999, 104: 466-472. 10.1016/S0091-6749(99)70395-7.CrossRefPubMed
17.
go back to reference Atherton DJ, Sewell M, Soothill JF, Wells RS, Chilvers CE: A double-blind controlled crossover trial of an antigen-avoidance diet in atopic eczema. Lancet. 1978, 1: 401-403.CrossRefPubMed Atherton DJ, Sewell M, Soothill JF, Wells RS, Chilvers CE: A double-blind controlled crossover trial of an antigen-avoidance diet in atopic eczema. Lancet. 1978, 1: 401-403.CrossRefPubMed
18.
go back to reference Nowak-Wegrzyn A, Assa’ad AH, Bahna SL, Bock SA, Sicherer SH, SS Work Group report: Oral food challenge testing. J Allergy Clin Immunol. 2009, 123: S365-S383. 10.1016/j.jaci.2009.03.042.CrossRefPubMed Nowak-Wegrzyn A, Assa’ad AH, Bahna SL, Bock SA, Sicherer SH, SS Work Group report: Oral food challenge testing. J Allergy Clin Immunol. 2009, 123: S365-S383. 10.1016/j.jaci.2009.03.042.CrossRefPubMed
19.
go back to reference Sampson HA, van Wijk RG, Bindslev-Jensen C, Sicherer SH, Teuber SS, Burks AW, Dubois AEI, Beyer K, Eigenmann PA, Spergel JM, Werfel T, Chinchilli VM: Standardizing double-blind, placebo-controlled oral foodchallenges: American Academy of Allergy, Asthma & Immunology–European Academy of Allergy and Clinical Immunology PRACTALL consensus report. J Allergy Clin Immunol. 2012, 130: 1260-1274. 10.1016/j.jaci.2012.10.017.CrossRefPubMed Sampson HA, van Wijk RG, Bindslev-Jensen C, Sicherer SH, Teuber SS, Burks AW, Dubois AEI, Beyer K, Eigenmann PA, Spergel JM, Werfel T, Chinchilli VM: Standardizing double-blind, placebo-controlled oral foodchallenges: American Academy of Allergy, Asthma & Immunology–European Academy of Allergy and Clinical Immunology PRACTALL consensus report. J Allergy Clin Immunol. 2012, 130: 1260-1274. 10.1016/j.jaci.2012.10.017.CrossRefPubMed
20.
go back to reference Bindslev-Jensen C, Ballmer-Weber BK, Bengtsson U: Standardization of food challenges in patients with immediate reactions to foods – position paper from the European Academy of Allergology and Clinical Immunology. Allergy. 2004, 59: 690-697. 10.1111/j.1398-9995.2004.00466.x.CrossRefPubMed Bindslev-Jensen C, Ballmer-Weber BK, Bengtsson U: Standardization of food challenges in patients with immediate reactions to foods – position paper from the European Academy of Allergology and Clinical Immunology. Allergy. 2004, 59: 690-697. 10.1111/j.1398-9995.2004.00466.x.CrossRefPubMed
21.
go back to reference Caffarelli C, Petroccione T: False-negative food challenge in children with suspected food allergy. Lancet. 2001, 358: 1871-1872. 10.1016/S0140-6736(01)06897-0.CrossRefPubMed Caffarelli C, Petroccione T: False-negative food challenge in children with suspected food allergy. Lancet. 2001, 358: 1871-1872. 10.1016/S0140-6736(01)06897-0.CrossRefPubMed
22.
go back to reference Caffarelli C, Ricò S, Rinaldi L, Povesi Dascola C, Terzi C, Bernasconi S: Blood pressure monitoring in children undergoing food challenge: association with anaphylaxis. Ann Allergy Asthma Immunol. 2012, 108: 285-286. 10.1016/j.anai.2012.02.001.CrossRefPubMed Caffarelli C, Ricò S, Rinaldi L, Povesi Dascola C, Terzi C, Bernasconi S: Blood pressure monitoring in children undergoing food challenge: association with anaphylaxis. Ann Allergy Asthma Immunol. 2012, 108: 285-286. 10.1016/j.anai.2012.02.001.CrossRefPubMed
23.
go back to reference Johnke H, Norberg LA, Vach W, Host A, Andersen KE: Patterns of sensitization in infants and its relation to atopic dermatitis. Pediatr Allergy Immunol. 2006, 17: 591-600. 10.1111/j.1399-3038.2006.00453.x.CrossRefPubMed Johnke H, Norberg LA, Vach W, Host A, Andersen KE: Patterns of sensitization in infants and its relation to atopic dermatitis. Pediatr Allergy Immunol. 2006, 17: 591-600. 10.1111/j.1399-3038.2006.00453.x.CrossRefPubMed
24.
go back to reference Lever R: The role of food in atopic eczema. J Am Acad Dermatol. 2001, 45: 57-60. 10.1067/mjd.2001.117012.CrossRef Lever R: The role of food in atopic eczema. J Am Acad Dermatol. 2001, 45: 57-60. 10.1067/mjd.2001.117012.CrossRef
25.
go back to reference Rennick GJ, Moore E, Orchard DC: Skin prick testing to food allergens in breast-fed young infants with moderate to severe atopic dermatitis. Australas J Dermatol. 2006, 47: 41-45. 10.1111/j.1440-0960.2006.00221.x.CrossRefPubMed Rennick GJ, Moore E, Orchard DC: Skin prick testing to food allergens in breast-fed young infants with moderate to severe atopic dermatitis. Australas J Dermatol. 2006, 47: 41-45. 10.1111/j.1440-0960.2006.00221.x.CrossRefPubMed
26.
go back to reference Eigenmann PA, Sicherer SH, Borkowski TA, Cohen BA, Sampson HA: Prevalence of IgE mediated food allergy among children with atopic dermatitis. Pediatrics. 1998, 101: 8-CrossRef Eigenmann PA, Sicherer SH, Borkowski TA, Cohen BA, Sampson HA: Prevalence of IgE mediated food allergy among children with atopic dermatitis. Pediatrics. 1998, 101: 8-CrossRef
27.
28.
go back to reference Burks AW, James JM, Hiegel A, Wilson G, Wheeler JG, Jones SM, Zuerlein N: Atopic dermatitis and food hypersensitivity reactions. J Pediatr. 1998, 132: 132-136. 10.1016/S0022-3476(98)70498-6.CrossRefPubMed Burks AW, James JM, Hiegel A, Wilson G, Wheeler JG, Jones SM, Zuerlein N: Atopic dermatitis and food hypersensitivity reactions. J Pediatr. 1998, 132: 132-136. 10.1016/S0022-3476(98)70498-6.CrossRefPubMed
29.
go back to reference Guillet G, Guillet MH: Natural history of sensitizations in atopic dermatitis. A 3-year follow-up in 250 children: food allergy and high risk of respiratory symptoms. Arch Dermatol. 1992, 128: 187-192. 10.1001/archderm.1992.01680120059004.CrossRefPubMed Guillet G, Guillet MH: Natural history of sensitizations in atopic dermatitis. A 3-year follow-up in 250 children: food allergy and high risk of respiratory symptoms. Arch Dermatol. 1992, 128: 187-192. 10.1001/archderm.1992.01680120059004.CrossRefPubMed
30.
go back to reference Hill DJ, Hosking CS: Food allergy and atopic dermatitis in infancy: an epidemiologic study. Pediatr Allergy Immunol. 2004, 15: 421-427. 10.1111/j.1399-3038.2004.00178.x.CrossRefPubMed Hill DJ, Hosking CS: Food allergy and atopic dermatitis in infancy: an epidemiologic study. Pediatr Allergy Immunol. 2004, 15: 421-427. 10.1111/j.1399-3038.2004.00178.x.CrossRefPubMed
31.
go back to reference Boyce JA, Assa’ad A, Burks AW, Jones SM, Sampson HA, Wood RA, Plaut M, Cooper SF, Fenton MJ, Arshad SH, Bahna SL, Beck LA, Byrd-Bredbenner C, Camargo CA, Eichenfield L, Furuta GT, Hanifin JM, Jones C, Kraft M, Levy BD, Lieberman P, Luccioli S, McCall KM, Schneider LC, Simon RA, Simons FE, Teach SJ, Yawn BP, Schwaninger JM: Guidelines for the diagnosis and management of food allergy in the united states: Report of the NIAID-Sponsored Expert Panel. J Allergy Clin Immunol. 2010, 126: S1-S58.PubMedCentralCrossRefPubMed Boyce JA, Assa’ad A, Burks AW, Jones SM, Sampson HA, Wood RA, Plaut M, Cooper SF, Fenton MJ, Arshad SH, Bahna SL, Beck LA, Byrd-Bredbenner C, Camargo CA, Eichenfield L, Furuta GT, Hanifin JM, Jones C, Kraft M, Levy BD, Lieberman P, Luccioli S, McCall KM, Schneider LC, Simon RA, Simons FE, Teach SJ, Yawn BP, Schwaninger JM: Guidelines for the diagnosis and management of food allergy in the united states: Report of the NIAID-Sponsored Expert Panel. J Allergy Clin Immunol. 2010, 126: S1-S58.PubMedCentralCrossRefPubMed
32.
go back to reference Povesi Dascola C, Caffarelli C: Exercise-induced anaphylaxis: a clinical view. Ital J Ped. 2012, 38: 43-10.1186/1824-7288-38-43.CrossRef Povesi Dascola C, Caffarelli C: Exercise-induced anaphylaxis: a clinical view. Ital J Ped. 2012, 38: 43-10.1186/1824-7288-38-43.CrossRef
33.
go back to reference Caffarelli C, Cavagni G, Giordano S, Stapane I, Rossi C: Relationship between oral challenges with previously uningested egg and egg-specific IgE antibodies and skin prick tests in infants with food allergy. J Allergy Clin lmmunol. 1995, 951: 15-20. Caffarelli C, Cavagni G, Giordano S, Stapane I, Rossi C: Relationship between oral challenges with previously uningested egg and egg-specific IgE antibodies and skin prick tests in infants with food allergy. J Allergy Clin lmmunol. 1995, 951: 15-20.
34.
go back to reference Johannsen H, Nolan R, Pascoe EM, Cuthbert P, Noble V, Corderoy T, Franzmann A, Loh R, Prescott SL: Skin prick testing and peanut-specific IgE can predict peanut challenge outcomes in preschool children with peanut sensitization. Clin Exp Allergy. 2011, 41: 994-1000. 10.1111/j.1365-2222.2011.03717.x.CrossRefPubMed Johannsen H, Nolan R, Pascoe EM, Cuthbert P, Noble V, Corderoy T, Franzmann A, Loh R, Prescott SL: Skin prick testing and peanut-specific IgE can predict peanut challenge outcomes in preschool children with peanut sensitization. Clin Exp Allergy. 2011, 41: 994-1000. 10.1111/j.1365-2222.2011.03717.x.CrossRefPubMed
35.
go back to reference Rhodes HL, Thomas P, Sporik R, Holgate ST, Cogswell JJ: A birth cohort study of subjects at risk of atopy: twenty-two-year follow-up of wheeze and atopic status. Am J Respir Crit Care Med. 2002, 15: 176-180.CrossRef Rhodes HL, Thomas P, Sporik R, Holgate ST, Cogswell JJ: A birth cohort study of subjects at risk of atopy: twenty-two-year follow-up of wheeze and atopic status. Am J Respir Crit Care Med. 2002, 15: 176-180.CrossRef
36.
go back to reference Dean T, Venter C, Pereira B, Harsad HS, Grundy J, Clayton BC, Higgins B: Patterns of sensitization to food and aeroallergens in the first 3 years of life. J Allergy Clin Immunol. 2007, 120: 1166-1171. 10.1016/j.jaci.2007.06.042.CrossRefPubMed Dean T, Venter C, Pereira B, Harsad HS, Grundy J, Clayton BC, Higgins B: Patterns of sensitization to food and aeroallergens in the first 3 years of life. J Allergy Clin Immunol. 2007, 120: 1166-1171. 10.1016/j.jaci.2007.06.042.CrossRefPubMed
37.
go back to reference Tariq SM, Matthews SM, Hakim EA, Arshad SH: Egg allergy in infancy predicts respiratory allergic disease by 4 years of age. Pediatr Allergy Immunol. 2000, 11: 162-167. 10.1034/j.1399-3038.2000.00077.x.CrossRefPubMed Tariq SM, Matthews SM, Hakim EA, Arshad SH: Egg allergy in infancy predicts respiratory allergic disease by 4 years of age. Pediatr Allergy Immunol. 2000, 11: 162-167. 10.1034/j.1399-3038.2000.00077.x.CrossRefPubMed
38.
go back to reference Burr ML, Merrett TG, Dunstan FD, Maguire MJ: The development of allergy in high-risk children. Clin Exp Allergy. 1997, 27: 1247-1253. 10.1111/j.1365-2222.1997.tb01168.x.CrossRefPubMed Burr ML, Merrett TG, Dunstan FD, Maguire MJ: The development of allergy in high-risk children. Clin Exp Allergy. 1997, 27: 1247-1253. 10.1111/j.1365-2222.1997.tb01168.x.CrossRefPubMed
39.
go back to reference Lowe AJ, Hosking CS, Bennett CM: Skin prick test can identify eczematous infants at risk of asthma and allergic rhinitis. Clin Exp Allergy. 2007, 37: 1624-1631. 10.1111/j.1365-2222.2007.02822.x.CrossRefPubMed Lowe AJ, Hosking CS, Bennett CM: Skin prick test can identify eczematous infants at risk of asthma and allergic rhinitis. Clin Exp Allergy. 2007, 37: 1624-1631. 10.1111/j.1365-2222.2007.02822.x.CrossRefPubMed
40.
go back to reference Kjaer HF, Eller E, Andersen KE, Høst A, Bindslev-Jensen C: The association between early sensitization patterns and subsequent allergic disease. The DARC birth cohort study. Pediatr Allergy Immunol. 2009, 20: 726-734. 10.1111/j.1399-3038.2009.00862.x.CrossRefPubMed Kjaer HF, Eller E, Andersen KE, Høst A, Bindslev-Jensen C: The association between early sensitization patterns and subsequent allergic disease. The DARC birth cohort study. Pediatr Allergy Immunol. 2009, 20: 726-734. 10.1111/j.1399-3038.2009.00862.x.CrossRefPubMed
41.
go back to reference Bernstein IL, Li JT, Bernstein DI, Hamilton R, Spector SL, Tan R, Sicherer S, Golden DB, Khan DA, Nicklas RA, Portnoy JM, Blessing-Moore J, Cox L, Lang DM, Oppenheimer J, Randolph CC, Schuller DE, Tilles SA, Wallace DV, Levetin E, Weber R, American Academy of Allergy, Asthma and Immunology; American College of Allergy, Asthma and Immunology: Allergy diagnostic testing: an updated practice parameter. Ann Allergy Asthma Immunol. 2008, 100 (Suppl. 3): S1-S148. Bernstein IL, Li JT, Bernstein DI, Hamilton R, Spector SL, Tan R, Sicherer S, Golden DB, Khan DA, Nicklas RA, Portnoy JM, Blessing-Moore J, Cox L, Lang DM, Oppenheimer J, Randolph CC, Schuller DE, Tilles SA, Wallace DV, Levetin E, Weber R, American Academy of Allergy, Asthma and Immunology; American College of Allergy, Asthma and Immunology: Allergy diagnostic testing: an updated practice parameter. Ann Allergy Asthma Immunol. 2008, 100 (Suppl. 3): S1-S148.
42.
go back to reference Bernhisel-Broadbent J: Allergenic cross-reactivity of foods and characterization of food allergens and extracts. Ann Allergy Asthma Immunol. 1995, 75: 295-303.PubMed Bernhisel-Broadbent J: Allergenic cross-reactivity of foods and characterization of food allergens and extracts. Ann Allergy Asthma Immunol. 1995, 75: 295-303.PubMed
43.
go back to reference Sampson HA: Comparative study of commercial food antigen extracts for the diagnosis of food hypersensitivity. J Allergy Clin Immunol. 1988, 82: 718-726. 10.1016/0091-6749(88)90070-X.CrossRefPubMed Sampson HA: Comparative study of commercial food antigen extracts for the diagnosis of food hypersensitivity. J Allergy Clin Immunol. 1988, 82: 718-726. 10.1016/0091-6749(88)90070-X.CrossRefPubMed
44.
go back to reference Wang J, Godbold JH, Sampson HA: Correlation of serum allergy (IgE) tests performed by different assay systems. J Allergy Clin Immunol. 2008, 121: 1219-1224. 10.1016/j.jaci.2007.12.1150.CrossRefPubMed Wang J, Godbold JH, Sampson HA: Correlation of serum allergy (IgE) tests performed by different assay systems. J Allergy Clin Immunol. 2008, 121: 1219-1224. 10.1016/j.jaci.2007.12.1150.CrossRefPubMed
45.
go back to reference Rosen J, Selcow J, Mendelson L, Grodofsky M, Factor J, Sampson H: Skin testing with natural foods in patients suspected of having food allergies.is it necessary?. J Allergy Clin Immunol. 1994, 93: 1068-1070. 10.1016/S0091-6749(94)70056-7.CrossRefPubMed Rosen J, Selcow J, Mendelson L, Grodofsky M, Factor J, Sampson H: Skin testing with natural foods in patients suspected of having food allergies.is it necessary?. J Allergy Clin Immunol. 1994, 93: 1068-1070. 10.1016/S0091-6749(94)70056-7.CrossRefPubMed
46.
go back to reference Alessandri C, Zennaro D, Scala E, Ferrara R, Bernardi ML, Santoro M, Palazzo P, Mari A: Ovomucoid (Gal d 1) specific IgE detected by microarray system predict tolerability to boiled hen’s egg and an increased risk to progress to multiple environmental allergen sensitization. Clin Exp Allergy. 2011, 42: 441-450.CrossRefPubMed Alessandri C, Zennaro D, Scala E, Ferrara R, Bernardi ML, Santoro M, Palazzo P, Mari A: Ovomucoid (Gal d 1) specific IgE detected by microarray system predict tolerability to boiled hen’s egg and an increased risk to progress to multiple environmental allergen sensitization. Clin Exp Allergy. 2011, 42: 441-450.CrossRefPubMed
47.
go back to reference Huang F, Nowak-Wegrzyn A: Extensively heated milk and egg as oral immunotherapy. Curr Opin Allergy Clin Immunol. 2012, 12: 283-292. 10.1097/ACI.0b013e3283535bc3.CrossRefPubMed Huang F, Nowak-Wegrzyn A: Extensively heated milk and egg as oral immunotherapy. Curr Opin Allergy Clin Immunol. 2012, 12: 283-292. 10.1097/ACI.0b013e3283535bc3.CrossRefPubMed
48.
go back to reference Bath-Hextall FJ, Delamere FM, Williams HC: Dietary exclusions for established atopic eczema. Cochrane Database of Systematic Reviews. 2008, Issue 1 Bath-Hextall FJ, Delamere FM, Williams HC: Dietary exclusions for established atopic eczema. Cochrane Database of Systematic Reviews. 2008, Issue 1
49.
go back to reference Ricci G, Dondi A, Patrizi A: Useful tools for the management of atopic dermatitis. Am J Clin Dermatol. 2009, 10: 287-300. 10.2165/11310760-000000000-00000.CrossRefPubMed Ricci G, Dondi A, Patrizi A: Useful tools for the management of atopic dermatitis. Am J Clin Dermatol. 2009, 10: 287-300. 10.2165/11310760-000000000-00000.CrossRefPubMed
50.
51.
go back to reference Flintermann AE, Knulst AC, Meijer Y, Bruijnzeel-Koomen CA, Pasmans SG: Acute allergic reactions in children with AEDS after prolonged cow’s milk elimination diets. Allergy. 2006, 61: 370-374. 10.1111/j.1398-9995.2006.01018.x.CrossRef Flintermann AE, Knulst AC, Meijer Y, Bruijnzeel-Koomen CA, Pasmans SG: Acute allergic reactions in children with AEDS after prolonged cow’s milk elimination diets. Allergy. 2006, 61: 370-374. 10.1111/j.1398-9995.2006.01018.x.CrossRef
52.
go back to reference Noimark L, Cox HE: Nutritional problems related to food allergy in childhood. Pediatr Allergy Immunol. 2008, 19: 188-195. 10.1111/j.1399-3038.2007.00700.x.CrossRefPubMed Noimark L, Cox HE: Nutritional problems related to food allergy in childhood. Pediatr Allergy Immunol. 2008, 19: 188-195. 10.1111/j.1399-3038.2007.00700.x.CrossRefPubMed
53.
go back to reference Williams HC, Burney PG, Hay RJ, Archer CB, Shipley MJ, Hunter JJ: The UK Working Party’s Diagnostic Criteria for Atopic Dermatitis. I. Derivation of a minimum set of discriminators for atopic dermatitis. Br J Dermatol. 1994, 131: 383-96. 10.1111/j.1365-2133.1994.tb08530.x.CrossRefPubMed Williams HC, Burney PG, Hay RJ, Archer CB, Shipley MJ, Hunter JJ: The UK Working Party’s Diagnostic Criteria for Atopic Dermatitis. I. Derivation of a minimum set of discriminators for atopic dermatitis. Br J Dermatol. 1994, 131: 383-96. 10.1111/j.1365-2133.1994.tb08530.x.CrossRefPubMed
54.
go back to reference Hanifin JM, Rajka G: Diagnostic features of atopic dermatitis. Acta Dermatol Venereol. 1980, 92: 44-47. Hanifin JM, Rajka G: Diagnostic features of atopic dermatitis. Acta Dermatol Venereol. 1980, 92: 44-47.
55.
go back to reference Flohr C, Johansson SGO, Wahlgren CF, Williams H: How atopic is atopic dermatitis?. J Allergy Clin Immunol. 2004, 113: 150-8.CrossRef Flohr C, Johansson SGO, Wahlgren CF, Williams H: How atopic is atopic dermatitis?. J Allergy Clin Immunol. 2004, 113: 150-8.CrossRef
56.
go back to reference Lowe AJ, Abramson MJ, Hosking CS, Carlin JB, Bennett CM, Dharmage SC, Hill DJ: The temporal sequence of allergic sensitization and onset of infantile eczema. Clin Exp Allergy. 2007, 37: 536-542. 10.1111/j.1365-2222.2007.02691.x.CrossRefPubMed Lowe AJ, Abramson MJ, Hosking CS, Carlin JB, Bennett CM, Dharmage SC, Hill DJ: The temporal sequence of allergic sensitization and onset of infantile eczema. Clin Exp Allergy. 2007, 37: 536-542. 10.1111/j.1365-2222.2007.02691.x.CrossRefPubMed
57.
go back to reference Celik-Bilgili S, Mehl A, Verstege A, Staden U, Nocon M, Beyer K, Niggemann B: The predictive value of specific immunoglobulin E levels in serum for the outcome of oral food challenges. Clin Exp Allergy. 2005, 35: 268-73. 10.1111/j.1365-2222.2005.02150.x.CrossRefPubMed Celik-Bilgili S, Mehl A, Verstege A, Staden U, Nocon M, Beyer K, Niggemann B: The predictive value of specific immunoglobulin E levels in serum for the outcome of oral food challenges. Clin Exp Allergy. 2005, 35: 268-73. 10.1111/j.1365-2222.2005.02150.x.CrossRefPubMed
58.
go back to reference Böhme M, Svensson A, Kull I, Nordvall SL, Wahlgren CF: Clinical features of atopic dermatitis at two years of age: a prospective, population-based case–control study. Acta Derm Venereol. 2001, 81: 193-7. 10.1080/000155501750376294.CrossRefPubMed Böhme M, Svensson A, Kull I, Nordvall SL, Wahlgren CF: Clinical features of atopic dermatitis at two years of age: a prospective, population-based case–control study. Acta Derm Venereol. 2001, 81: 193-7. 10.1080/000155501750376294.CrossRefPubMed
59.
go back to reference Patrizi A, Guerrini V, Ricci G, Neri I, Specchia F, Masi M: The natural history of sensitization to food and aeroallergens in atopic dermatitis: a 4-year follow-up. Pediatr Dermatol. 2000, 17: 261-5. 10.1046/j.1525-1470.2000.01771.x.CrossRefPubMed Patrizi A, Guerrini V, Ricci G, Neri I, Specchia F, Masi M: The natural history of sensitization to food and aeroallergens in atopic dermatitis: a 4-year follow-up. Pediatr Dermatol. 2000, 17: 261-5. 10.1046/j.1525-1470.2000.01771.x.CrossRefPubMed
60.
go back to reference Wolkerstorfer A, Wahn U, Kjellman NIM, Diepgen TL, De Longueville M, Oranje AP: Natural course of sensitization to cow’s milk and hen’s egg in childhood atopic dermatitis: ETAC Study Group. Clin Exp Allergy. 2002, 32: 70-3. 10.1046/j.0022-0477.2001.01265.x.CrossRefPubMed Wolkerstorfer A, Wahn U, Kjellman NIM, Diepgen TL, De Longueville M, Oranje AP: Natural course of sensitization to cow’s milk and hen’s egg in childhood atopic dermatitis: ETAC Study Group. Clin Exp Allergy. 2002, 32: 70-3. 10.1046/j.0022-0477.2001.01265.x.CrossRefPubMed
61.
go back to reference Novembre E, Cianferoni A, Lombardi E, Bernardini R, Pucci N, Vierucci A: Natural history of intrinsic atopic dermatitis. Allergy. 2001, 56: 452-63. 10.1034/j.1398-9995.2001.056005452.x.CrossRefPubMed Novembre E, Cianferoni A, Lombardi E, Bernardini R, Pucci N, Vierucci A: Natural history of intrinsic atopic dermatitis. Allergy. 2001, 56: 452-63. 10.1034/j.1398-9995.2001.056005452.x.CrossRefPubMed
62.
go back to reference Wuthrich B, Schmid-Grendelmeier P: Natural course of AEDS. Allergy. 2002, 57: 267-8. 10.1034/j.1398-9995.2002.1n3572.x.CrossRefPubMed Wuthrich B, Schmid-Grendelmeier P: Natural course of AEDS. Allergy. 2002, 57: 267-8. 10.1034/j.1398-9995.2002.1n3572.x.CrossRefPubMed
63.
go back to reference Eller E, Kjaer HF, Høst A, Andersen KE, Bindslev-Jensen C: Development of atopic dermatitis in the DARC birth cohort. Pediatr Allergy Immunol. 2009, 21: 307-314.CrossRefPubMed Eller E, Kjaer HF, Høst A, Andersen KE, Bindslev-Jensen C: Development of atopic dermatitis in the DARC birth cohort. Pediatr Allergy Immunol. 2009, 21: 307-314.CrossRefPubMed
Metadata
Title
Skin prick test to foods in childhood atopic eczema: pros and cons
Authors
Carlo Caffarelli
Arianna Dondi
Carlotta Povesi Dascola
Giampaolo Ricci
Publication date
01-12-2013
Publisher
BioMed Central
Published in
Italian Journal of Pediatrics / Issue 1/2013
Electronic ISSN: 1824-7288
DOI
https://doi.org/10.1186/1824-7288-39-48

Other articles of this Issue 1/2013

Italian Journal of Pediatrics 1/2013 Go to the issue