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Archives of Virology
Published in: Archives of Virology 4/2016

Open Access 01-04-2016 | Brief Report

Multiple viral introductions: molecular characterization of influenza B virus in Wenzhou, Zhejiang, China, from 2011 to 2014 based on hemagglutinin and neuraminidase genes

Authors: Dong Chen, Xiaohong Wen, Yi Sun, Haiyan Mao, Yanjun Zhang, Yin Chen, Xinying Wang, Baochang Sun, Xin Wang, Xiaoming Zhang

Published in: Archives of Virology | Issue 4/2016

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Abstract

Influenza B virus is a major causative agent of respiratory disease in humans. Our study of an outbreak of influenza B virus in Wenzhou from 2011 to 2014 revealed that 163 (5.58 %) of 2921 samples were influenza B positive. Sequencing of the hemagglutinin and neuraminidase genes showed substitutions at the amino acid level. Phylogenetic analysis revealed co-circulation of the B/Victoria and B/Yamagata lineages in the Wenzhou area from 2011 to 2014. Multiple viral introductions from both Chinese and international sources played important roles in endemic co-circulation and transmission in coastal southeastern China.
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Literature
1.
2.
Tan Y, Guan WD, Lam TTY, Pan SH, Wu SG, Zhan YQ, Viboud C, Holmes EC, Yang ZF (2013) Differing epidemiological dynamics of influenza B virus lineages in Guangzhou, Southern China, 2009–2010. J Virol 87:12447–12456CrossRefPubMedPubMedCentral
3.
Zhu N, Li P, Yu JF, Li YD, Zhao JR, Xia H, Tang S, Zhang Z, Kou Z, Yin SY, Fan ZJ, Li TX (2013) Molecular characterization of influenza B viruses isolated in east-central China in 2009–2010. Virus Genes 46:28–38CrossRefPubMed
4.
Ali G, Amer HM, Ahnajhdi FN (2014) Hemagglutini and neuraminidase genes of influenza B viruses circulating in Riyadh, Saudi Arabia during 2010–2011: evolution and sequence analysis. J Med Virol 86:1003–1016CrossRefPubMed
5.
Kaneage Y, Sugita S, Endo A, Ishida M, Senya S, Osako K, Nerome K, Oya A (1990) Evolutionary pattern of the hemagglutinin gene of influenza B viruses isolated in Japan: cocirculating lineages in the same epidemic season. J Virol 64:2860–2865
6.
Rota PA, Wallis TR, Harmon MW, Rota JS, Kendal AP, Nerome K (1990) Cocirculation of two distinct evolutionary lineages of influenza type B virus since 1983. Virology 175:59–68CrossRefPubMed
7.
Tewawong N, Suwannakarn K, Prachayangprecha S, Korkong S, Vichiwattana P, Vongpunsawad S, Poovorawan Y (2015) Molecular epidemiology and phylogenetic analyses of influenza B virus in Thailand during 2010 to 2014. PLoS One 10(1):e0116302CrossRefPubMedPubMedCentral
8.
Burnet SFM (1955) Principles of animal virology. Academic Press, New York
9.
Hay AJ, Gregory V, Douglas AR, Lin YP (2000) The evolution of human influenza viruses. Philos Trans R Soc Lond B Biol Sci 356:1861–1870
10.
Bedford T, Suchard MA, Lerney P, Dudas G, Gregory V, Hay AJ, McCauley JW, Russell CA, Smith DJ, Rambaut A (2014) Integrating influenza antigenic dynamics with molecular evolution. eLife 3:e01914CrossRefPubMedPubMedCentral
11.
Fang QX, Gao Y, Chen MF, Guo XL, Yang X, Wei L (2015) Molecular epidemiology and evolution of influenza A and B viruses during winter 2013–2014 in Beijing, China. Arch Virol 160:1083–1095CrossRefPubMed
12.
Posada D, Crandall KA (1998) Modeltest: testing the model of DNA substitution. Bioinformatics 14:817–818CrossRefPubMed
13.
14.
WHO (2014) Review of the 2013–2014 winter influenza season, northern hemisphere. WER 89:245–256
15.
Zaman RU, Alamgir ASM, Rahman M, Azziz-Baumgartner E, Gurley ES, Sharker MAY, Brooks WA, Azim T, Fry AM, Lindstrom S, Gubareva LV, Xu X, Garten RJ, Hossain MJ, Khan SU, Faruque LI, Ameer SS, Klimov AI, Rahman M, Luby SP (2009) Influenza in outpatient ILI case-patients in national hospital-based surveillance, Bangladesh, 2007–2008. PLoS One 29(4):e8452CrossRef
16.
17.
Verhoeyen M, Van Rompuy L, Jou WM, Huylebroeck D, Fiers W (1983) Complete nucleotide sequence of the influenza B/Singapore/222/79 virus hemagglutinin gene and comparison with the B/Lee/40 hemagglutinin. Nucleic Acids Res 11:4703–4712CrossRefPubMedPubMedCentral
18.
Ni F, Kondrashkina E, Wang Q (2013) Structural basis of the divergent evolution of influenza B virus hemagglutinin. Virology 446:113–122
19.
Bedford T, Nelson MJ, Chan KH, Chen R, Vijaykrishna D, Halpin RA, Stockwell TB, Lin X, Wentworth DE, Ghedin E, Guan Y, Peiris JS, Riley S, Rambaut A, Holmes EC, Smith GJ (2011) Temporally structured metapopulation dynamics and persistence of influenza A H3N2 virus in human. Proc. Natl Acad Sci USA 108:19359–19364CrossRef
20.
Cheng X, Tan Y, He M, Lam TT, Lu X, Viboud C, He J, Zhang S, Lu J, Wu C, Fang S, Wang X, Xie X, Ma H, Nelson MJ, Kung HF, Holmes EC (2013) Epidemiological dynamics and phylogeography of influenza in southern China. J Infect Dis 207:106–114CrossRefPubMedPubMedCentral
21.
Nelson MI, Edelman L, Spiro DJ, Boyne AR, Bera J, Halpin R, Sengamalay N, Ghedin E, Miller MA, Simonsen L, Viboud C, Holmes EC (2008) Molecular epidemiology of A/H3N2 and A/H1N1 influenza virus during a single epidemic season in the United States. PLoS Pathog 4:e1000133CrossRefPubMedPubMedCentral
22.
Sun Y, Yan JY, Mao HY, Zhang L, Lyu QF, Wu ZH, Zheng W, Feng C, Zhang YJ (2013) Characterization of the complete genome of Chikungunya in Zhejiang, China, using a modified virus discovery method based on cDNA-AFLP. PLoS One 8:e83914CrossRef
23.
Zhang YJ, Mao HY, Yan JY, Zhang L, Sun Y, Wang XY, Chen Y, Lu YY, Chen EF, Lv HK, Gong LM, Li Z, Gao J, Xu CP, Feng Y, Ge Q, Xu BX, Xu F, Yang ZN, Zhao GQ, Han JK, Guus K, Li H, Shu YL, Chen ZP, Xia SC (2014) Isolation and characterization of H7N9 avian influenza A virus from humans with respiratory disease in Zhejiang, China. Virus Res 189:158–164CrossRefPubMed
24.
Mao HY, Guo B, Wang FY, Sun Y, Lou XY, Chen Y, Zhang L, Wang XY, Li Z, Liu SL, Qin SW, Wei JC, Pang ZF, Chen ZP, Zhang YJ (2015) A study of family clustering in two young girls with novel avian influenza A (H7N9) in Dongyang, Zhejiang Province, in 2014. J Clin Virol 63:18–24CrossRefPubMed
Metadata
Title
Multiple viral introductions: molecular characterization of influenza B virus in Wenzhou, Zhejiang, China, from 2011 to 2014 based on hemagglutinin and neuraminidase genes
Authors
Dong Chen
Xiaohong Wen
Yi Sun
Haiyan Mao
Yanjun Zhang
Yin Chen
Xinying Wang
Baochang Sun
Xin Wang
Xiaoming Zhang
Publication date
01-04-2016
Publisher
Springer Vienna
Published in
Archives of Virology / Issue 4/2016
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-015-2721-7

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