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Open Access 01-12-2020 | Mood Disorders | Research article

Healthy Options: study protocol and baseline characteristics for a cluster randomized controlled trial of group psychotherapy for perinatal women living with HIV and depression in Tanzania

Authors: Mary C. Smith Fawzi, Hellen Siril, Elysia Larson, Zenaice Aloyce, Ricardo Araya, Anna Kaale, Janeth Kamala, Muhummed Nadeem Kasmani, Amina Komba, Anna Minja, Angelina Mwimba, Fileuka Ngakongwa, Magreat Somba, Christopher R. Sudfeld, Sylvia F. Kaaya

Published in: BMC Public Health | Issue 1/2020

Abstract

Background

Perinatal women accessing prevention of mother-to-child transmission of HIV (PMTCT) services are at an increased risk of depression; however, in Tanzania there is limited access to services provided by mental health professionals. This paper presents a protocol and baseline characteristics for a study evaluating a psychosocial support group intervention facilitated by lay community-based health workers (CBHWs) for perinatal women living with HIV and depression in Dar es Salaam.

Methods

A cluster randomized controlled trial (RCT) is conducted comparing: 1) a psychosocial support group intervention; and 2) improved standard of mental health care. The study is implemented in reproductive and child health (RCH) centers providing PMTCT services. Baseline characteristics are presented by comparing sociodemographic characteristics and primary as well as secondary outcomes for the trial for intervention and control groups. The trial is registered under clinicaltrials.gov (NCT02039973).

Results

Among 742 women enrolled, baseline characteristics were comparable for intervention and control groups, although more women in the control group had completed secondary school (25.2% versus 18.2%). Overall, findings suggest that the population is highly vulnerable with over 45% demonstrating food insecurity and 17% reporting intimate partner violence in the past 6 months.

Conclusions

Baseline characteristics for the cluster RCT were comparable for intervention and control groups. The trial will examine the effectiveness of a psychosocial support group intervention for the treatment of depression among women living with HIV accessing PMTCT services. A reduction in the burden of depression in this vulnerable population has implications in the short-term for improved HIV-related outcomes and for potential long-term effects on child growth and development.

Trial registration

The trial is registered under clinicaltrials.gov (NCT02039973). Retrospectively registered on January 20, 2014.

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Title: Healthy Options: study protocol and baseline characteristics for a cluster randomized controlled trial of group psychotherapy for perinatal women living with HIV and depression in Tanzania
Authors: Mary C. Smith Fawzi
Hellen Siril
Elysia Larson
Zenaice Aloyce
Ricardo Araya
Anna Kaale
Janeth Kamala
Muhummed Nadeem Kasmani
Amina Komba
Anna Minja
Angelina Mwimba
Fileuka Ngakongwa
Magreat Somba
Christopher R. Sudfeld
Sylvia F. Kaaya
Publication date: 01-12-2020
Publisher: BioMed Central
Keywords: Mood Disorders
Human Immunodeficiency Virus
Affective Disorder
Published in: BMC Public Health / Issue 1/2020
Electronic ISSN: 1471-2458
DOI: https://doi.org/10.1186/s12889-019-7907-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Healthy Options: study protocol and baseline characteristics for a cluster randomized controlled trial of group psychotherapy for perinatal women living with HIV and depression in Tanzania

Abstract

Background

Methods

Results

Conclusions

Trial registration

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

Trial registration

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