Issue 1/2009
Content (76 Articles)
Role of acid-sensing ion channel 3 in sub-acute-phase inflammation
Yi-Tin Yen, Pan-Hsien Tu, Chien-Ju Chen, Yi-Wen Lin, Sung-Tsang Hsieh, Chih-Cheng Chen
Glycine receptor in rat hippocampal and spinal cord neurons as a molecular target for rapid actions of 17-β-estradiol
Peng Jiang, Yan Kong, Xiao-Bing Zhang, Wei Wang, Chun-Feng Liu, Tian-Le Xu
Pore dilation occurs in TRPA1 but not in TRPM8 channels
Jun Chen, Donghee Kim, Bruce R Bianchi, Eric J Cavanaugh, Connie R Faltynek, Philip R Kym, Regina M Reilly
Enhanced quantal release of excitatory transmitter in anterior cingulate cortex of adult mice with chronic pain
Hiroki Toyoda, Ming-Gao Zhao, Min Zhuo
Modulation of transient receptor potential vanilloid 4-mediated membrane currents and synaptic transmission by protein kinase C
De-Shou Cao, Shuang-Quan Yu, Louis S Premkumar
Enhanced pre-synaptic glutamate release in deep-dorsal horn contributes to calcium channel alpha-2-delta-1 protein-mediated spinal sensitization and behavioral hypersensitivity
David Nguyen, Ping Deng, Elizabeth A Matthews, Doo-Sik Kim, Guoping Feng, Anthony H Dickenson, Zao C Xu, Z David Luo
Correlational analysis for identifying genes whose regulation contributes to chronic neuropathic pain
Anna-Karin Persson, Mathias Gebauer, Suzana Jordan, Christiane Metz-Weidmann, Anke M Schulte, Hans-Christoph Schneider, Danping Ding-Pfennigdorff, Jonas Thun, Xiao-Jun Xu, Zsuzsanna Wiesenfeld-Hallin, Ariel Darvasi, Kaj Fried, Marshall Devor
Effects of removal of dietary polyunsaturated fatty acids on plasma extravasation and mechanical allodynia in a trigeminal neuropathic pain model
Yasmina B Martin, Carlos Avendaño
Mice with cisplatin and oxaliplatin-induced painful neuropathy develop distinct early responses to thermal stimuli
Lauren E Ta, Philip A Low, Anthony J Windebank
Peripheral nerve injury sensitizes neonatal dorsal horn neurons to tumor necrosis factor-α
Jie Li, Wenrui Xie, Jun-Ming Zhang, Mark L Baccei
Gz mediates the long-lasting desensitization of brain CB1 receptors and is essential for cross-tolerance with morphine
Javier Garzón, Elena de la Torre-Madrid, María Rodríguez-Muñoz, Ana Vicente-Sánchez, Pilar Sánchez-Blázquez
Nitric oxide activates ATP-sensitive potassium channels in mammalian sensory neurons: action by direct S-nitrosylation
Takashi Kawano, Vasiliki Zoga, Masakazu Kimura, Mei-Ying Liang, Hsiang-En Wu, Geza Gemes, J Bruce McCallum, Wai-Meng Kwok, Quinn H Hogan, Constantine D Sarantopoulos
Characterization of NF-kB-mediated inhibition of catechol-O-methyltransferase
Inna E Tchivileva, Andrea G Nackley, Li Qian, Sean Wentworth, Matthew Conrad, Luda B Diatchenko
Increased peripheral nerve excitability and local NaV1.8 mRNA up-regulation in painful neuropathy
Devang Kashyap Thakor, Audrey Lin, Yoshizo Matsuka, Edward M Meyer, Supanigar Ruangsri, Ichiro Nishimura, Igor Spigelman
Plasticity in expression of the glutamate transporters GLT-1 and GLAST in spinal dorsal horn glial cells following partial sciatic nerve ligation
Wen-Jun Xin, Han-Rong Weng, Patrick M Dougherty
Transforming growth factor-β1 impairs neuropathic pain through pleiotropic effects
Stefania Echeverry, Xiang Qun Shi, Alexandra Haw, Hong Liu, Zhong-wei Zhang, Ji Zhang
High concentrations of morphine sensitize and activate mouse dorsal root ganglia via TRPV1 and TRPA1 receptors
Alexander B Forster, Peter W Reeh, Karl Messlinger, Michael JM Fischer
Behavioural and electrophysiological characterisation of experimentally induced osteoarthritis and neuropathy in C57Bl/6 mice
Victoria L Harvey, Anthony H Dickenson
Pharmacological blockade of TRPA1 inhibits mechanical firing in nociceptors
Patrick C Kerstein, Donato del Camino, Magdalene M Moran, Cheryl L Stucky
Antidepressants inhibit P2X4 receptor function: a possible involvement in neuropathic pain relief
Kenichiro Nagata, Toshiyasu Imai, Tomohiro Yamashita, Makoto Tsuda, Hidetoshi Tozaki-Saitoh, Kazuhide Inoue
NR2B receptor blockade inhibits pain-related sensitization of amygdala neurons
Guangchen Ji, Csilla Horváth, Volker Neugebauer
Activation of cytosolic phospholipase A2 in dorsal root ganglion neurons by Ca2+/calmodulin-dependent protein kinase II after peripheral nerve injury
Shigeo Hasegawa, Yuta Kohro, Makoto Tsuda, Kazuhide Inoue
Intrathecal delivery of PDGF produces tactile allodynia through its receptors in spinal microglia
Junya Masuda, Makoto Tsuda, Hidetoshi Tozaki-Saitoh, Kazuhide Inoue
Inhibitory coupling between inhibitory interneurons in the spinal cord dorsal horn
Charalampos Labrakakis, Louis-Etienne Lorenzo, Cyril Bories, Alfredo Ribeiro-da-Silva, Yves De Koninck
Cannabinoid receptor type 2 activation induces a microglial anti-inflammatory phenotype and reduces migration via MKP induction and ERK dephosphorylation
Edgar Alfonso Romero-Sandoval, Ryan Horvath, Russell P Landry, Joyce A DeLeo
NF-κB mediated enhancement of potassium currents by the chemokine CXCL1/growth related oncogene in small diameter rat sensory neurons
Rui-Hua Yang, Judith A Strong, Jun-Ming Zhang
Formalin-induced behavioural hypersensitivity and neuronal hyperexcitability are mediated by rapid protein synthesis at the spinal level
Curtis O Asante, Victoria C Wallace, Anthony H Dickenson
Behavioral phenotypes of mice lacking purinergic P2X4 receptors in acute and chronic pain assays
Makoto Tsuda, Kazuya Kuboyama, Tomoyuki Inoue, Kenichiro Nagata, Hidetoshi Tozaki-Saitoh, Kazuhide Inoue
An in vivo mouse model of long-term potentiation at synapses between primary afferent C-fibers and spinal dorsal horn neurons: essential role of EphB1 receptor
Wen-Tao Liu, Yuan Han, Hao-Chuan Li, Brandt Adams, Ji-Hong Zheng, Yong-Ping Wu, Mark Henkemeyer, Xue-Jun Song
Challenges of functional imaging research of pain in children
Simona Sava, Alyssa A Lebel, David S Leslie, Athena Drosos, Charles Berde, Lino Becerra, David Borsook
Reactive oxygen species mediate TNFR1 increase after TRPV1 activation in mouse DRG neurons
Fei Ma, Liping Zhang, Karin N Westlund
Ethnicity and OPRM variant independently predict pain perception and patient-controlled analgesia usage for post-operative pain
Ene-choo Tan, Eileen CP Lim, Yik-ying Teo, Yvonne Lim, Hai-yang Law, Alex T Sia
PKCε-dependent potentiation of TTX-resistant Nav1.8 current by neurokinin-1 receptor activation in rat dorsal root ganglion neurons
Chun-Lei Cang, Hua Zhang, Yu-Qiu Zhang, Zhi-Qi Zhao
Excitatory neurotransmitters in brain regions in interictal migraine patients
Andrew Prescot, Lino Becerra, Gautam Pendse, Shannon Tully, Eric Jensen, Richard Hargreaves, Perry Renshaw, Rami Burstein, David Borsook
Minocycline treatment inhibits microglial activation and alters spinal levels of endocannabinoids in a rat model of neuropathic pain
Leonardo Guasti, Denise Richardson, Maulik Jhaveri, Khalil Eldeeb, David Barrett, Maurice R Elphick, Stephen PH Alexander, David Kendall, Gregory J Michael, Victoria Chapman
Synaptically evoked glutamate transporter currents in Spinal Dorsal Horn Astrocytes
Haijun Zhang, Wenjun Xin, Patrick M Dougherty
Genetic variation in the serotonin transporter gene (5-HTTLPR, rs25531) influences the analgesic response to the short acting opioid Remifentanil in humans
Eva Kosek, Karin B Jensen, Tina B Lonsdorf, Martin Schalling, Martin Ingvar
Evidence for a role of NTS2 receptors in the modulation of tonic pain sensitivity
Geneviève Roussy, Marc-André Dansereau, Stéphanie Baudisson, Faouzi Ezzoubaa, Karine Belleville, Nicolas Beaudet, Jean Martinez, Elliott Richelson, Philippe Sarret
Expression and function of proton-sensing G-protein-coupled receptors in inflammatory pain
Ying-Ju Chen, Chia-Wei Huang, Chih-Shin Lin, Wen-Han Chang, Wei-Hsin Sun
Translocation of neuronal nitric oxide synthase to the plasma membrane by ATP is mediated by P2X and P2Y receptors
Takayuki Ohnishi, Shinji Matsumura, Seiji Ito
Antinociception induced by chronic glucocorticoid treatment is correlated to local modulation of spinal neurotransmitter content
Filipa Pinto-Ribeiro, Vitor Moreira, José M Pêgo, Pedro Leão, Armando Almeida, Nuno Sousa
Adenovector GAD65 gene delivery into the rat trigeminal ganglion produces orofacial analgesia
Jean-Philippe Vit, Peter T Ohara, Christopher Sundberg, Blanca Rubi, Pierre Maechler, Chunyan Liu, Mariana Puntel, Pedro Lowenstein, Maria Castro, Luc Jasmin
Proinflammatory-activated trigeminal satellite cells promote neuronal sensitization: relevance for migraine pathology
Alessandro Capuano, Alice De Corato, Lucia Lisi, Giuseppe Tringali, Pierluigi Navarra, Cinzia Dello Russo
The endogenous hydrogen sulfide producing enzyme cystathionine-β synthase contributes to visceral hypersensitivity in a rat model of irritable bowel syndrome
Guang-Yin Xu, John H Winston, Mohan Shenoy, Shufang Zhou, Jiande DZ Chen, Pankaj J Pasricha
Descending serotonergic facilitation and the antinociceptive effects of pregabalin in a rat model of osteoarthritic pain
Wahida Rahman, Claudia S Bauer, Kirsty Bannister, Jean-Laurent Vonsy, Annette C Dolphin, Anthony H Dickenson
Roles of the AMPA receptor subunit GluA1 but not GluA2 in synaptic potentiation and activation of ERK in the anterior cingulate cortex
Hiroki Toyoda, Ming-Gao Zhao, Bettina Ulzhöfer, Long-Jun Wu, Hui Xu, Peter H Seeburg, Rolf Sprengel, Rohini Kuner, Min Zhuo
Subtype-specific regulation of P2X3 and P2X2/3 receptors by phosphoinositides in peripheral nociceptors
Gary Mo, Louis-Philippe Bernier, Qi Zhao, Anne-Julie Chabot-Doré, Ariel R Ase, Diomedes Logothetis, Chang-Qing Cao, Philippe Séguéla
Increased chemokine signaling in a model of HIV1-associated peripheral neuropathy
Sonia K Bhangoo, Matthew S Ripsch, David J Buchanan, Richard J Miller, Fletcher A White
Tumor necrosis factor-alpha (TNF-α) enhances functional thermal and chemical responses of TRP cation channels in human synoviocytes
Mikhail Y Kochukov, Terry A McNearney, Huaizhi Yin, Liping Zhang, Fei Ma, Larissa Ponomareva, Sarah Abshire, Karin N Westlund
Signal Transduction Mechanisms Underlying Group I mGluR-mediated Increase in Frequency and Amplitude of Spontaneous EPSCs in the Spinal Trigeminal Subnucleus Oralis of the Rat
Ji-Hyeon Song, Eun-Sung Park, Sang-Mi Han, Seung-Ro Han, Dong-Kuk Ahn, Dong-Ho Youn
Short-term synaptic plasticity in the nociceptive thalamic-anterior cingulate pathway
Bai-Chuang Shyu, Brent A Vogt
Recombinant adeno-associated virus serotype 6 (rAAV2/6)-mediated gene transfer to nociceptive neurons through different routes of delivery
Chris Towne, Marie Pertin, Ahmed T Beggah, Patrick Aebischer, Isabelle Decosterd
Large A-fiber activity is required for microglial proliferation and p38 MAPK activation in the spinal cord: different effects of resiniferatoxin and bupivacaine on spinal microglial changes after spared nerve injury
Marc R Suter, Temugin Berta, Yong-Jing Gao, Isabelle Decosterd, Ru-Rong Ji
NMDA receptor subunit expression and PAR2 receptor activation in colospinal afferent neurons (CANs) during inflammation induced visceral hypersensitivity
Shelby K Suckow, Robert M Caudle
Nociception-induced spatial and temporal plasticity of synaptic connection and function in the hippocampal formation of rats: a multi-electrode array recording
Xiao-Yan Zhao, Ming-Gang Liu, Dong-Liang Yuan, Yan Wang, Ying He, Dan-Dan Wang, Xue-Feng Chen, Fu-Kang Zhang, Hua Li, Xiao-Sheng He, Jun Chen
Do genetic predictors of pain sensitivity associate with persistent widespread pain?
Kate L Holliday, Barbara I Nicholl, Gary J Macfarlane, Wendy Thomson, Kelly A Davies, John McBeth
Delayed onset of changes in soma action potential genesis in nociceptive A-beta DRG neurons in vivo in a rat model of osteoarthritis
Qi Wu, James L Henry
Involvement of S-nitrosylation of actin in inhibition of neurotransmitter release by nitric oxide
Jingshan Lu, Tayo Katano, Emiko Okuda-Ashitaka, Yo Oishi, Yoshihiro Urade, Seiji Ito
Dynamic regulation of the endocannabinoid system: implications for analgesia
Devi Rani Sagar, A Gemma Gaw, Bright N Okine, Stephen G Woodhams, Amy Wong, David A Kendall, Victoria Chapman
Morphine modulation of pain processing in medial and lateral pain pathways
Jin-Yan Wang, Jin Huang, Jing-Yu Chang, Donald J Woodward, Fei Luo
In vivo evidence that truncated trkB.T1 participates in nociception
Cynthia L Renn, Carmen C Leitch, Susan G Dorsey
Differential role of the menthol-binding residue Y745 in the antagonism of thermally gated TRPM8 channels
Annika Malkia, María Pertusa, Gregorio Fernández-Ballester, Antonio Ferrer-Montiel, Félix Viana
Antinociceptive action of oxytocin involves inhibition of potassium channel currents in lamina II neurons of the rat spinal cord
Jean Didier Breton, Pierrick Poisbeau, Pascal Darbon
Lysophosphatidic acid-3 receptor-mediated feed-forward production of lysophosphatidic acid: an initiator of nerve injury-induced neuropathic pain
Lin Ma, Hitoshi Uchida, Jun Nagai, Makoto Inoue, Jerold Chun, Junken Aoki, Hiroshi Ueda
Different forms of glycine- and GABAA-receptor mediated inhibitory synaptic transmission in mouse superficial and deep dorsal horn neurons
Wayne B Anderson, Brett A Graham, Natalie J Beveridge, Paul A Tooney, Alan M Brichta, Robert J Callister
Oxaliplatin-induced loss of phosphorylated heavy neurofilament subunit neuronal immunoreactivity in rat DRG tissue
Stephen MF Jamieson, Joshuan Subramaniam, Johnson J Liu, Nancy N Jong, Virginia Ip, Bronwen Connor, Mark J McKeage
Effective relief of neuropathic pain by adeno-associated virus-mediated expression of a small hairpin RNA against GTP cyclohydrolase 1
Sung Jin Kim, Won Il Lee, Yoon Sun Lee, Dong Hou Kim, Jin Woo Chang, Seong Who Kim, Heuiran Lee
Conditional gene deletion reveals functional redundancy of GABAB receptors in peripheral nociceptors in vivo
Vijayan Gangadharan, Nitin Agarwal, Stefan Brugger, Imgard Tegeder, Bernhard Bettler, Rohini Kuner, Martina Kurejova
Differential regulation of immune responses and macrophage/neuron interactions in the dorsal root ganglion in young and adult rats following nerve injury
David Vega-Avelaira, Sandrine M Géranton, Maria Fitzgerald
A role of periaqueductal grey NR2B-containing NMDA receptor in mediating persistent inflammatory pain
Jing Hu, Zhe Wang, Yan-Yan Guo, Xiao-Nan Zhang, Zhao-Hui Xu, Shui-Bing Liu, Hong-Ju Guo, Qi Yang, Fu-Xing Zhang, Xiao-Li Sun, Ming-Gao Zhao
Peripheral non-viral MIDGE vector-driven delivery of β-endorphin in inflammatory pain
Halina Machelska, Matthias Schroff, Detlef Oswald, Waltraud Binder, Nicolle Sitte, Shaaban A Mousa, Heike L Rittner, Alexander Brack, Dominika Labuz, Melanie Busch, Burghardt Wittig, Michael Schäfer, Christoph Stein
Characterization of intrinsic properties of cingulate pyramidal neurons in adult mice after nerve injury
Xiao-Yan Cao, Hui Xu, Long-Jun Wu, Xiang-Yao Li, Tao Chen, Min Zhuo
Upregulation of casein kinase 1ε in dorsal root ganglia and spinal cord after mouse spinal nerve injury contributes to neuropathic pain
Eri Sakurai, Takashi Kurihara, Kasumi Kouchi, Hironao Saegusa, Shuqin Zong, Tsutomu Tanabe
Differential involvement of trigeminal transition zone and laminated subnucleus caudalis in orofacial deep and cutaneous hyperalgesia: the effects of interleukin-10 and glial inhibitors
Kohei Shimizu, Wei Guo, Hu Wang, Shiping Zou, Stacey C LaGraize, Koichi Iwata, Feng Wei, Ronald Dubner, Ke Ren
Tyrosine phosphorylation of the N-Methyl-D-Aspartate receptor 2B subunit in spinal cord contributes to remifentanil-induced postoperative hyperalgesia: the preventive effect of ketamine
Xiaoping Gu, Xiaoli Wu, Yue Liu, Songqin Cui, Zhengliang Ma