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Graefe's Archive for Clinical and Experimental Ophthalmology

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01-11-2020 | Migraine | Neurophthalmology

Evaluation of retinal vessel density and choriocapillaris flow in migraine patients with and without aura

Authors: Pınar Bingöl Kızıltunç, Gökçen Özcan, Ferhad Özer, Canan Togay Işıkay, Huban Atilla

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 11/2020

Abstract

Purpose

Migraine is thought to be a neurovascular disorder and increases the likelyhood to develop ischemic complications. Studies have shown that vascular disorders such as ischemic optic neuropathy, retinal artery and vein obstructions are more common in patients with migraine. This study aimed to evaluate the differences between retinal and optic disc microvasculature between migraine patients with and without aura and healthy controls using optical coherence tomography angiography (OCTA) imaging.

Methods

Thirty-three patients with migraine and 28 healthy subjects were included in this prospective cross sectional study. Optical coherence tomography angiography imaging was performed for the macula and optic disc. Vessel densities (VD) and choriocapillaris flow values were compared between three groups: control group, migraine with aura (MWA), and migraine without aura (MWOA).

Results

There was no difference between the three groups for the VDs of the foveal, perifoveal, parafoveal, and the whole area. The choriocapillaris flow of patients with MWA was significantly less than that of the MWOA and control groups. The VDs of the optic disc revealed no significant difference between the three groups.

Conclusion

A lack of choriocapillaris autoregulatory mechanisms may be a possible cause of the decrease in choriocapillaris flow in patients with MWA.

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Title: Evaluation of retinal vessel density and choriocapillaris flow in migraine patients with and without aura
Authors: Pınar Bingöl Kızıltunç
Gökçen Özcan
Ferhad Özer
Canan Togay Işıkay
Huban Atilla
Publication date: 01-11-2020
Publisher: Springer Berlin Heidelberg
Keywords: Migraine
Angiography
Aura
Published in: Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 11/2020
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-020-04805-6

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Evaluation of retinal vessel density and choriocapillaris flow in migraine patients with and without aura

Abstract

Purpose

Methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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