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Open Access 14-06-2023 | Metastasis | Original Article

Outcomes of surgical resection for pulmonary metastasis from pancreatic cancer

Authors: Yudai Miyashita, Naoko Ose, Jiro Okami, Koji Takami, Yasushi Sakamaki, Naoki Ikeda, Masanobu Hayakawa, Masahiko Higashiyama, Ken Kodama, Yoshiyuki Susaki, Yasunobu Funakoshi, Jun Maeda, Yasushi Shintani

Published in: Surgery Today | Issue 11/2023

Abstract

Purpose

As the number of long-term survivors of pancreatic cancer is expected to increase thanks to recent advances in multidisciplinary treatment and earlier diagnoses of pancreatic cancer, we are likely to encounter more cases of postoperative pulmonary nodules. We analyzed the clinical course and prognosis of resection of pulmonary metastases from pancreatic cancer to clarify the prognostic implication of pulmonary metastasectomy for pancreatic cancer.

Method

We retrospectively analyzed 35 patients who underwent resection of lung metastases after pancreatic cancer surgery. Short- and long-term outcomes and factors associated with the prognosis were analyzed.

Results

The observation period was 20 (range, 1–101) months, with 3- and 5-year survival rates of 88.3% and 64.5% from pancreatectomy and 44.1% and 28.3% from lung resection, respectively. A univariate analysis revealed that a period from pancreatic cancer resection to pulmonary nodule shadow detection of < 15 months was associated with a significantly lower overall survival from pancreatic resection than a longer period. Conversely, histological type, stage, size of lung metastases, and resection technique were not associated with the overall survival.

Conclusion

A long-term prognosis may be expected in some cases with a disease-free interval of ≥ 15 months. Our findings suggest that the disease-free interval may influence the prognosis.

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Title: Outcomes of surgical resection for pulmonary metastasis from pancreatic cancer
Authors: Yudai Miyashita
Naoko Ose
Jiro Okami
Koji Takami
Yasushi Sakamaki
Naoki Ikeda
Masanobu Hayakawa
Masahiko Higashiyama
Ken Kodama
Yoshiyuki Susaki
Yasunobu Funakoshi
Jun Maeda
Yasushi Shintani
Publication date: 14-06-2023
Publisher: Springer Nature Singapore
Keywords: Metastasis
Pulmonary Nodule
Pancreatic Cancer
Pancreatic Cancer
Published in: Surgery Today / Issue 11/2023
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI: https://doi.org/10.1007/s00595-023-02701-0

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Outcomes of surgical resection for pulmonary metastasis from pancreatic cancer

Abstract

Purpose

Method

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Method

Results

Conclusion

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