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Published in: Child's Nervous System 6/2009

01-06-2009 | Case Report

Metachronous gliomas following cranial irradiation for mixed germ cell tumors

Authors: Akari Makidono, Nobuo Kobayashi, Yukihisa Saida, Atsushi Manabe, Jiro Kawamori, Koyu Suzuki

Published in: Child's Nervous System | Issue 6/2009

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Abstract

Introduction

Cranial irradiation has been widely used as a therapeutic tool for treating various lesions, particularly neoplastic diseases. Even though radiation therapy is usually well-tolerated, it occasionally causes clinically significant long-term toxicity such as radiation necrosis and irradiation-related arteriopathy with stroke.

Discussion and case report

The development of neoplasms following therapeutic cranial irradiation is also rare, but may cause serious and potentially fatal complications. Various radiation-induced tumors, including meningioma, glioma, and sarcoma have been reported (Child Nerv Syst 24:793–805, 12). However, metachronous intracranial double tumors induced by radiation therapy are extremely rare. In here, we report a case of metachronous different gliomas including astrocytoma and glioblastoma following irradiation therapy after 41 and 46 months, respectively.
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Metadata
Title
Metachronous gliomas following cranial irradiation for mixed germ cell tumors
Authors
Akari Makidono
Nobuo Kobayashi
Yukihisa Saida
Atsushi Manabe
Jiro Kawamori
Koyu Suzuki
Publication date
01-06-2009
Publisher
Springer-Verlag
Published in
Child's Nervous System / Issue 6/2009
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-009-0829-3

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