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Child's Nervous System

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01-09-2006 | Case Report

Metachronous secondary atypical meningioma and anaplastic astrocytoma after postoperative craniospinal irradiation for medulloblastoma

Authors: Andrew J. Hope, David B. Mansur, Pang-Hsien Tu, Joseph R. Simpson

Published in: Child's Nervous System | Issue 9/2006

Abstract

Introduction

Malignant brain tumors have been reported to occur after childhood irradiation more frequently than in the nonirradiated population.

Discussion

In this study, we report the case of a 15-year-old boy treated for medulloblastoma with surgery and craniospinal radiotherapy, who developed a meningioma 18 years after initial treatment and subsequently an anaplastic astrocytoma 23 years after primary treatment. The meningioma was resected without complications. The patient is currently alive but with recurrent astrocytoma after a complete remission on temozolomide monotherapy. Second malignancies are a rare, potentially devastating risk in cancer survivors, with risk continuing lifelong.

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Title: Metachronous secondary atypical meningioma and anaplastic astrocytoma after postoperative craniospinal irradiation for medulloblastoma
Authors: Andrew J. Hope
David B. Mansur
Pang-Hsien Tu
Joseph R. Simpson
Publication date: 01-09-2006
Publisher: Springer-Verlag
Published in: Child's Nervous System / Issue 9/2006
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI: https://doi.org/10.1007/s00381-006-0062-2

At a glance: The STEP trials

Springer Medicine

Metachronous secondary atypical meningioma and anaplastic astrocytoma after postoperative craniospinal irradiation for medulloblastoma

Abstract

Introduction

Discussion

At a glance: The STEP trials

Springer Medicine

Abstract

Introduction

Discussion

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