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Neurosurgical Review
Published in: Neurosurgical Review 4/2003

01-10-2003 | Neurooncology

Multicentric glioma: our experience in 25 patients and critical review of the literature

Authors: Maurizio Salvati, Emanuela Caroli, Epimenio Ramundo Orlando, Alessandro Frati, Spartaco Artizzu, Luigi Ferrante

Published in: Neurosurgical Review | Issue 4/2003

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Abstract

Multicentric gliomas are interesting and well-recognised entities with a yet unknown rate of occurrence. Single cases or small series are reported in the literature accessible to us, and we think this is the first large series describing true multicentric gliomas. We reviewed 25 patients selected according to the criteria defined by Batzdorf and Malamud. Multicentricity was found in 2% of patients with malignant gliomas. Longer survival was observed in patients who underwent surgical excision of the multicentric lesions. Multicentric tumours are rare clinical entities. Our data suggest that they should be surgically removed whenever possible, and histopathologic examination of the lesions is always advisable if they are located in sites inaccessible to surgery. Stereotactic biopsy represents a safe and satisfactory method for achieving sure diagnosis.
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Metadata
Title
Multicentric glioma: our experience in 25 patients and critical review of the literature
Authors
Maurizio Salvati
Emanuela Caroli
Epimenio Ramundo Orlando
Alessandro Frati
Spartaco Artizzu
Luigi Ferrante
Publication date
01-10-2003
Publisher
Springer-Verlag
Published in
Neurosurgical Review / Issue 4/2003
Print ISSN: 0344-5607
Electronic ISSN: 1437-2320
DOI
https://doi.org/10.1007/s10143-003-0276-7

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