Skip to main content
Top
Published in: Insights into Imaging 1/2023

Open Access 01-12-2023 | Mesothelioma | Educational Review

Primary and secondary tumors of the peritoneum: key imaging features and differential diagnosis with surgical and pathological correlation

Authors: Javier Miguez González, Francesc Calaf Forn, Laura Pelegrí Martínez, Pilar Lozano Arranz, Rafael Oliveira Caiafa, Jordi Català Forteza, Lina Maria Palacio Arteaga, Ferrán Losa Gaspà, Isabel Ramos Bernadó, Pedro Barrios Sánchez, Juan Ramón Ayuso Colella

Published in: Insights into Imaging | Issue 1/2023

Login to get access

Abstract

Peritoneal malignancies represent a diagnostic challenge for abdominal radiologists, oncologists, surgeons and pathologists in multidisciplinary teams, who must address their differential diagnosis, staging and treatment. In this article, we explain the pathophysiology of these processes and lay out the role of different imaging techniques in their evaluation. Then, we review the clinical and epidemiological aspects, the main radiological features and the therapeutic approaches for each primary and secondary peritoneal neoplasm, with surgical and pathological correlation. We further describe other rare peritoneal tumors of uncertain origin and a variety of entities that may mimic peritoneal malignancy. Finally, we summarize the key imaging findings of each peritoneal neoplasm to facilitate an accurate differential diagnosis that may impact patient management.
Clinical relevance statement
Imaging plays an essential role in the evaluation of peritoneal malignancies, assessing their extension, detecting unfavorable sites of involvement and facilitating an accurate differential diagnosis, helping to choose the best therapeutic approach.

Graphical abstract

Literature
1.
go back to reference Cortés-Guiral D, Martin HM, Alyami M et al (2021) Primary and metastatic peritoneal surface malignancies. Nat Rev Dis Primers 7:91PubMedCrossRef Cortés-Guiral D, Martin HM, Alyami M et al (2021) Primary and metastatic peritoneal surface malignancies. Nat Rev Dis Primers 7:91PubMedCrossRef
2.
go back to reference Levy AD, Arnaiz J, Shaw JC, Sobin LH (2008) From the archives of the AFIP: primary peritoneal tumors: imaging features with pathologic correlation. Radiographics 28(2):583–607PubMedCrossRef Levy AD, Arnaiz J, Shaw JC, Sobin LH (2008) From the archives of the AFIP: primary peritoneal tumors: imaging features with pathologic correlation. Radiographics 28(2):583–607PubMedCrossRef
3.
go back to reference Levy AD, Shaw JC, Sobin LH (2009) Secondary tumors and tumorlike lesions of the peritoneal cavity: imaging features with pathologic correlation. Radiographics 29(2):347–373PubMedCrossRef Levy AD, Shaw JC, Sobin LH (2009) Secondary tumors and tumorlike lesions of the peritoneal cavity: imaging features with pathologic correlation. Radiographics 29(2):347–373PubMedCrossRef
5.
go back to reference Diop AD, Fontarensky M, Montoriol PF, Da Ines D (2014) CT imaging of peritoneal carcinomatosis and its mimics. Diagn Interv Imaging 95(9):861–872PubMedCrossRef Diop AD, Fontarensky M, Montoriol PF, Da Ines D (2014) CT imaging of peritoneal carcinomatosis and its mimics. Diagn Interv Imaging 95(9):861–872PubMedCrossRef
6.
go back to reference Wilches C, Rivero OM, Aguirre DA (2010) Imaging evaluation of primary and secondary peritoneal malignancies. Rev Colomb Radiol 21(3):1–11 Wilches C, Rivero OM, Aguirre DA (2010) Imaging evaluation of primary and secondary peritoneal malignancies. Rev Colomb Radiol 21(3):1–11
7.
go back to reference Flanagan M, Solon J, Chang KH et al (2018) Peritoneal metastases from extra-abdominal cancer: a population-based study. Eur J Surg Oncol 44(11):1811–1817PubMedCrossRef Flanagan M, Solon J, Chang KH et al (2018) Peritoneal metastases from extra-abdominal cancer: a population-based study. Eur J Surg Oncol 44(11):1811–1817PubMedCrossRef
8.
go back to reference Meyers MA (1973) Distribution of intra-abdominal malignant seeding: dependency on dynamics of flow of ascitic fluid. AJR Am J Roentgenol Radium Ther Nucl Med 119:198–206CrossRef Meyers MA (1973) Distribution of intra-abdominal malignant seeding: dependency on dynamics of flow of ascitic fluid. AJR Am J Roentgenol Radium Ther Nucl Med 119:198–206CrossRef
10.
go back to reference Low RN, Barone RM, Lucero J (2015) Comparison of MRI and CT for predicting the peritoneal cancer index (PCI) preoperatively in patients being considered for cytoreductive surgical procedures. Ann Surg Oncol 22:1708–1715PubMedCrossRef Low RN, Barone RM, Lucero J (2015) Comparison of MRI and CT for predicting the peritoneal cancer index (PCI) preoperatively in patients being considered for cytoreductive surgical procedures. Ann Surg Oncol 22:1708–1715PubMedCrossRef
11.
go back to reference Koh J-L, Yan TD, Glenn D, Morris DL (2009) Evaluation of preoperative computed tomography in estimating peritoneal cancer index in colorectal peritoneal carcinomatosis. Ann Surg Oncol 16:327–333PubMedCrossRef Koh J-L, Yan TD, Glenn D, Morris DL (2009) Evaluation of preoperative computed tomography in estimating peritoneal cancer index in colorectal peritoneal carcinomatosis. Ann Surg Oncol 16:327–333PubMedCrossRef
12.
go back to reference Esquivel J, Chua TC, Stojadinovic A et al (2010) Accuracy and clinical relevance of computed tomography scan interpretation of peritoneal cancer index in colorectal cancer peritoneal carcinomatosis: a multi-institutional study. J Surg Oncol 102:565–570PubMedCrossRef Esquivel J, Chua TC, Stojadinovic A et al (2010) Accuracy and clinical relevance of computed tomography scan interpretation of peritoneal cancer index in colorectal cancer peritoneal carcinomatosis: a multi-institutional study. J Surg Oncol 102:565–570PubMedCrossRef
13.
go back to reference Aherne EA, Fenlon HM, Shields CJ, Mulsow JJ, Cronin CG (2017) What the radiologist should know about treatment of peritoneal malignancy. AJR Am J Roentgenol 208(3):531–543PubMedCrossRef Aherne EA, Fenlon HM, Shields CJ, Mulsow JJ, Cronin CG (2017) What the radiologist should know about treatment of peritoneal malignancy. AJR Am J Roentgenol 208(3):531–543PubMedCrossRef
14.
go back to reference Low RN, Barone RM (2012) Combined diffusion-weighted and gadolinium-enhanced MRI can accurately predict the peritoneal cancer index pre-operatively in patients being considered for cytoreductive surgical procedures. Ann Surg Oncol 19:1394–1401PubMedCrossRef Low RN, Barone RM (2012) Combined diffusion-weighted and gadolinium-enhanced MRI can accurately predict the peritoneal cancer index pre-operatively in patients being considered for cytoreductive surgical procedures. Ann Surg Oncol 19:1394–1401PubMedCrossRef
15.
go back to reference Low RN, Barone RM, Rousset P (2021) Peritoneal MRI in patients undergoing cytoreductive surgery and HIPEC: history, clinical applications, and implementation. Eur J Surg Oncol 47(1):65–74PubMedCrossRef Low RN, Barone RM, Rousset P (2021) Peritoneal MRI in patients undergoing cytoreductive surgery and HIPEC: history, clinical applications, and implementation. Eur J Surg Oncol 47(1):65–74PubMedCrossRef
16.
go back to reference Hewitt MJ, Anderson K, Hall GD et al (2007) Women with peritoneal carcinomatosis of unknown origin: efficacy of image-guided biopsy to determine site-specific diagnosis. BJOG 114(1):46–50PubMedCrossRef Hewitt MJ, Anderson K, Hall GD et al (2007) Women with peritoneal carcinomatosis of unknown origin: efficacy of image-guided biopsy to determine site-specific diagnosis. BJOG 114(1):46–50PubMedCrossRef
17.
go back to reference Jacquet P, Sugarbaker PH (1996) Clinical research methodologies in diagnosis and staging of patients with peritoneal carcinomatosis. Cancer Treat Res 82:359–374PubMedCrossRef Jacquet P, Sugarbaker PH (1996) Clinical research methodologies in diagnosis and staging of patients with peritoneal carcinomatosis. Cancer Treat Res 82:359–374PubMedCrossRef
18.
go back to reference Chandramohan A, Thrower A, Smith SA, Shah N, Moran B (2017) “PAUSE”: a method for communicating radiological extent of peritoneal malignancy. Clin Radiol 72:972–980PubMedCrossRef Chandramohan A, Thrower A, Smith SA, Shah N, Moran B (2017) “PAUSE”: a method for communicating radiological extent of peritoneal malignancy. Clin Radiol 72:972–980PubMedCrossRef
19.
go back to reference Chandramohan A, Shah N, Thrower A et al (2021) Communicating imaging findings in peritoneal mesothelioma: the impact of ‘PAUSE’ on surgical decision-making. Insights Imaging 12(1):174PubMedPubMedCentralCrossRef Chandramohan A, Shah N, Thrower A et al (2021) Communicating imaging findings in peritoneal mesothelioma: the impact of ‘PAUSE’ on surgical decision-making. Insights Imaging 12(1):174PubMedPubMedCentralCrossRef
21.
go back to reference Park JY, Kim KW, Kwon HJ et al (2008) Peritoneal mesotheliomas: clinicopathologic features, CT findings, and differential diagnosis. AJR Am J Roentgenol 191(3):814–825PubMedCrossRef Park JY, Kim KW, Kwon HJ et al (2008) Peritoneal mesotheliomas: clinicopathologic features, CT findings, and differential diagnosis. AJR Am J Roentgenol 191(3):814–825PubMedCrossRef
22.
go back to reference Husain AN, Colby TV, Ordóñez NG et al (2018) Guidelines for pathologic diagnosis of malignant mesothelioma 2017 update of the consensus statement from the international mesothelioma interest group. Arch Pathol Lab Med 142:89–108PubMedCrossRef Husain AN, Colby TV, Ordóñez NG et al (2018) Guidelines for pathologic diagnosis of malignant mesothelioma 2017 update of the consensus statement from the international mesothelioma interest group. Arch Pathol Lab Med 142:89–108PubMedCrossRef
23.
go back to reference Liang YF, Zheng GQ, Chen YF, Song H, Yin WJ, Zhang L (2016) CT differentiation of diffuse malignant peritoneal mesothelioma and peritoneal carcinomatosis. J Gastroenterol Hepatol 31(4):709–715PubMedCrossRef Liang YF, Zheng GQ, Chen YF, Song H, Yin WJ, Zhang L (2016) CT differentiation of diffuse malignant peritoneal mesothelioma and peritoneal carcinomatosis. J Gastroenterol Hepatol 31(4):709–715PubMedCrossRef
24.
go back to reference Yan TD, Deraco M, Baratti D et al (2009) Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for malignant peritoneal mesothelioma: multi-institutional experience. J Clin Oncol 27:6237–6242PubMedCrossRef Yan TD, Deraco M, Baratti D et al (2009) Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for malignant peritoneal mesothelioma: multi-institutional experience. J Clin Oncol 27:6237–6242PubMedCrossRef
25.
go back to reference Alexander HR, Bartlett DL, Pingpank JF et al (2013) Treatment factors associated with long-term survival after cytoreductive surgery and regional chemotherapy for patients with malignant peritoneal mesothelioma. Surgery 153:779–786PubMedCrossRef Alexander HR, Bartlett DL, Pingpank JF et al (2013) Treatment factors associated with long-term survival after cytoreductive surgery and regional chemotherapy for patients with malignant peritoneal mesothelioma. Surgery 153:779–786PubMedCrossRef
26.
go back to reference Hoekstra AV, Riben MW, Frumovitz M, Liu J, Ramirez PT (2005) Well-differentiated papillary mesothelioma of the peritoneum: a pathological analysis and review of the literature. Gynecol Oncol 98:161–167PubMedCrossRef Hoekstra AV, Riben MW, Frumovitz M, Liu J, Ramirez PT (2005) Well-differentiated papillary mesothelioma of the peritoneum: a pathological analysis and review of the literature. Gynecol Oncol 98:161–167PubMedCrossRef
27.
go back to reference Chand MT, Edens J, Lin T, Anderson I, Berri R (2020) Benign multicystic peritoneal mesothelioma: literature review and update. Autops Case Rep 10(3):e2020159PubMedPubMedCentralCrossRef Chand MT, Edens J, Lin T, Anderson I, Berri R (2020) Benign multicystic peritoneal mesothelioma: literature review and update. Autops Case Rep 10(3):e2020159PubMedPubMedCentralCrossRef
28.
go back to reference Lee R, Tong A, Kurtis B, Gilet AG (2016) Benign multicystic peritoneal mesothelioma: AIRP best cases in radiologic-pathologic correlation. Radiographics 36(2):407–411PubMedCrossRef Lee R, Tong A, Kurtis B, Gilet AG (2016) Benign multicystic peritoneal mesothelioma: AIRP best cases in radiologic-pathologic correlation. Radiographics 36(2):407–411PubMedCrossRef
29.
go back to reference Chua TC, Yan TD, Deraco M, Glehen O, Moran BJ, Sugarbaker PH (2011) Multi-institutional experience of diffuse intra-abdominal multicystic peritoneal mesothelioma. Br J Surg 98:60–64PubMedCrossRef Chua TC, Yan TD, Deraco M, Glehen O, Moran BJ, Sugarbaker PH (2011) Multi-institutional experience of diffuse intra-abdominal multicystic peritoneal mesothelioma. Br J Surg 98:60–64PubMedCrossRef
31.
go back to reference Morita H, Jun Aoki J, Taketomi A, Sato N, Endo K (2004) Serous surface papillary carcinoma of the peritoneum: clinical, radiologic, and pathologic findings in 11 patients. AJR Am J Roentgenol 183(4):923–928PubMedCrossRef Morita H, Jun Aoki J, Taketomi A, Sato N, Endo K (2004) Serous surface papillary carcinoma of the peritoneum: clinical, radiologic, and pathologic findings in 11 patients. AJR Am J Roentgenol 183(4):923–928PubMedCrossRef
33.
go back to reference Pickhardt PJ, Perez AA, Elmohr MM, Elsayes KM (2021) CT imaging review of uncommon peritoneal-based neoplasms: beyond carcinomatosis. Br J Radiol 94(1119):20201288PubMedPubMedCentralCrossRef Pickhardt PJ, Perez AA, Elmohr MM, Elsayes KM (2021) CT imaging review of uncommon peritoneal-based neoplasms: beyond carcinomatosis. Br J Radiol 94(1119):20201288PubMedPubMedCentralCrossRef
34.
go back to reference Boussios S, Sadauskaite A, Kanellos FS, Tsiouris AK, Karathanasi A, Sheriff M (2020) A narrative review of neoadjuvant, HIPEC and maintenance treatment in ovarian and peritoneal serous cancer: current status. Gynecol Pelvic Med 3:19CrossRef Boussios S, Sadauskaite A, Kanellos FS, Tsiouris AK, Karathanasi A, Sheriff M (2020) A narrative review of neoadjuvant, HIPEC and maintenance treatment in ovarian and peritoneal serous cancer: current status. Gynecol Pelvic Med 3:19CrossRef
35.
go back to reference Nougaret S, Addley HC, Colombo PE et al (2012) Ovarian carcinomatosis: how the radiologist can help plan the surgical approach. Radiographics 32(6):1775–1800PubMedCrossRef Nougaret S, Addley HC, Colombo PE et al (2012) Ovarian carcinomatosis: how the radiologist can help plan the surgical approach. Radiographics 32(6):1775–1800PubMedCrossRef
36.
go back to reference Pannu HK, Bristow RE, Montz FJ, Fishman EK (2003) Multidetector CT of peritoneal carcinomatosis from ovarian cancer. Radiographics 23:687–701PubMedCrossRef Pannu HK, Bristow RE, Montz FJ, Fishman EK (2003) Multidetector CT of peritoneal carcinomatosis from ovarian cancer. Radiographics 23:687–701PubMedCrossRef
37.
go back to reference Coakley FV, Choi PH, Gougoutas CA et al (2002) Peritoneal metastases: detection with spiral CT in patients with ovarian cancer. Radiology 223:495–499PubMedCrossRef Coakley FV, Choi PH, Gougoutas CA et al (2002) Peritoneal metastases: detection with spiral CT in patients with ovarian cancer. Radiology 223:495–499PubMedCrossRef
38.
go back to reference Lisio MA, Fu L, Goyeneche A, Gao ZH, Telleria C (2019) High-grade serous ovarian cancer: basic sciences, clinical and therapeutic standpoints. Int J Mol Sci 20(4):952PubMedPubMedCentralCrossRef Lisio MA, Fu L, Goyeneche A, Gao ZH, Telleria C (2019) High-grade serous ovarian cancer: basic sciences, clinical and therapeutic standpoints. Int J Mol Sci 20(4):952PubMedPubMedCentralCrossRef
39.
go back to reference Kurnit KC, Fleming GF, Lengyel E (2021) Updates and new options in advanced epithelial ovarian cancer treatment. Obstet Gynecol 137(1):108–121PubMedCrossRef Kurnit KC, Fleming GF, Lengyel E (2021) Updates and new options in advanced epithelial ovarian cancer treatment. Obstet Gynecol 137(1):108–121PubMedCrossRef
40.
go back to reference Lei Z, Wang Y, Wang J et al (2020) Evaluation of cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy for stage III epithelial ovarian cancer. JAMA Netw Open 3(8):e2013940PubMedPubMedCentralCrossRef Lei Z, Wang Y, Wang J et al (2020) Evaluation of cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy for stage III epithelial ovarian cancer. JAMA Netw Open 3(8):e2013940PubMedPubMedCentralCrossRef
41.
go back to reference Gaitskell K, Hermon C, Barnes I et al (2022) Ovarian cancer survival by stage, histotype, and pre-diagnostic lifestyle factors, in the prospective UK million women study. Cancer Epidemiol 76:102074PubMedPubMedCentralCrossRef Gaitskell K, Hermon C, Barnes I et al (2022) Ovarian cancer survival by stage, histotype, and pre-diagnostic lifestyle factors, in the prospective UK million women study. Cancer Epidemiol 76:102074PubMedPubMedCentralCrossRef
42.
go back to reference Nadler A, McCart JA, Govindarajan A (2015) Peritoneal carcinomatosis from colon cancer: a systematic review of the data for cytoreduction and intraperitoneal chemotherapy. Clin Colon Rectal Surg 28(4):234–246PubMedPubMedCentralCrossRef Nadler A, McCart JA, Govindarajan A (2015) Peritoneal carcinomatosis from colon cancer: a systematic review of the data for cytoreduction and intraperitoneal chemotherapy. Clin Colon Rectal Surg 28(4):234–246PubMedPubMedCentralCrossRef
43.
go back to reference Seyfried F, von Rahden BH, Miras AD et al (2015) Incidence, time course and independent risk factors for metachronous peritoneal carcinomatosis of gastric origin: a longitudinal experience from a prospectively collected database of 1108 patients. BMC Cancer 15:73PubMedPubMedCentralCrossRef Seyfried F, von Rahden BH, Miras AD et al (2015) Incidence, time course and independent risk factors for metachronous peritoneal carcinomatosis of gastric origin: a longitudinal experience from a prospectively collected database of 1108 patients. BMC Cancer 15:73PubMedPubMedCentralCrossRef
44.
go back to reference Sheth S, Horton KM, Garland MR, Fishman EK (2003) Mesenteric neoplasms: CT appearances of primary and secondary tumors and differential diagnosis. Radiographics 23:457–473PubMedCrossRef Sheth S, Horton KM, Garland MR, Fishman EK (2003) Mesenteric neoplasms: CT appearances of primary and secondary tumors and differential diagnosis. Radiographics 23:457–473PubMedCrossRef
45.
go back to reference Chang DK, Kim JW, Kim BK et al (2005) Clinical significance of CT-defined minimal ascites in patients with gastric cancer. World J Gastroenterol 11(42):6587–6592PubMedPubMedCentralCrossRef Chang DK, Kim JW, Kim BK et al (2005) Clinical significance of CT-defined minimal ascites in patients with gastric cancer. World J Gastroenterol 11(42):6587–6592PubMedPubMedCentralCrossRef
46.
go back to reference Zulfiqar M, Koen J, Nougaret S et al (2020) Krukenberg tumors: update on imaging and clinical features. AJR Am J Roentgenol 215(4):1020–1029PubMedCrossRef Zulfiqar M, Koen J, Nougaret S et al (2020) Krukenberg tumors: update on imaging and clinical features. AJR Am J Roentgenol 215(4):1020–1029PubMedCrossRef
47.
go back to reference Kianmanesh R, Ruszniewski P, Rindi G et al (2010) ENETS consensus guidelines for the management of peritoneal carcinomatosis from neuroendocrine tumors. Neuroendocrinology 91:333–340PubMedCrossRef Kianmanesh R, Ruszniewski P, Rindi G et al (2010) ENETS consensus guidelines for the management of peritoneal carcinomatosis from neuroendocrine tumors. Neuroendocrinology 91:333–340PubMedCrossRef
48.
go back to reference de Mestier L, Lardière-Deguelte S, Brixi H et al (2015) Updating the surgical management of peritoneal carcinomatosis in patients with neuroendocrine tumors. Neuroendocrinology 101:105–111PubMedCrossRef de Mestier L, Lardière-Deguelte S, Brixi H et al (2015) Updating the surgical management of peritoneal carcinomatosis in patients with neuroendocrine tumors. Neuroendocrinology 101:105–111PubMedCrossRef
49.
go back to reference Bhosale P, Shah A, Wei W et al (2013) Carcinoid tumours: predicting the location of the primary neoplasm based on the sites of metastases. Eur Radiol 23(2):400–407PubMedCrossRef Bhosale P, Shah A, Wei W et al (2013) Carcinoid tumours: predicting the location of the primary neoplasm based on the sites of metastases. Eur Radiol 23(2):400–407PubMedCrossRef
50.
go back to reference Leonards LM, Pahwa A, Patel MK, Petersen J, Nguyen MJ, Jude CM (2017) Neoplasms of the appendix: pictorial review with clinical and pathologic correlation. Radiographics 37(4):1059–1083PubMedCrossRef Leonards LM, Pahwa A, Patel MK, Petersen J, Nguyen MJ, Jude CM (2017) Neoplasms of the appendix: pictorial review with clinical and pathologic correlation. Radiographics 37(4):1059–1083PubMedCrossRef
51.
go back to reference Gupta A, Lubner MG, Menias CO, Mellnick VM, Elsayes KM, Pickhardt PJ (2019) Multimodality Imaging of ileal neuroendocrine (Carcinoid) tumor. AJR Am J Roentgenol 213(1):45–53PubMedCrossRef Gupta A, Lubner MG, Menias CO, Mellnick VM, Elsayes KM, Pickhardt PJ (2019) Multimodality Imaging of ileal neuroendocrine (Carcinoid) tumor. AJR Am J Roentgenol 213(1):45–53PubMedCrossRef
52.
go back to reference Bozkurt MF, Virgolini I, Balogova S et al (2017) Guideline for PET/CT imaging of neuroendocrine neoplasms with 68Ga-DOTA-conjugated somatostatin receptor targeting peptides and 18F-DOPA. Eur J Nucl Med Mol Imaging 44(9):1588–1601PubMedCrossRef Bozkurt MF, Virgolini I, Balogova S et al (2017) Guideline for PET/CT imaging of neuroendocrine neoplasms with 68Ga-DOTA-conjugated somatostatin receptor targeting peptides and 18F-DOPA. Eur J Nucl Med Mol Imaging 44(9):1588–1601PubMedCrossRef
53.
go back to reference Wong HH, Chu P (2012) Immunohistochemical features of the gastrointestinal tract tumors. J Gastrointest Oncol 3(3):262–284PubMedPubMedCentral Wong HH, Chu P (2012) Immunohistochemical features of the gastrointestinal tract tumors. J Gastrointest Oncol 3(3):262–284PubMedPubMedCentral
54.
go back to reference Foltyn W, Zajęcki W, Marek B et al (2012) The value of the Ki-67 proliferation marker as a prognostic factor in gastroenteropancreatic neuroendocrine tumours. Endokrynol Pol 63(5):362–366PubMed Foltyn W, Zajęcki W, Marek B et al (2012) The value of the Ki-67 proliferation marker as a prognostic factor in gastroenteropancreatic neuroendocrine tumours. Endokrynol Pol 63(5):362–366PubMed
55.
go back to reference Bellizzi AM (2020) Immunohistochemistry in the diagnosis and classification of neuroendocrine neoplasms: what can brown do for you? Hum Pathol 96:8–33PubMedCrossRef Bellizzi AM (2020) Immunohistochemistry in the diagnosis and classification of neuroendocrine neoplasms: what can brown do for you? Hum Pathol 96:8–33PubMedCrossRef
57.
go back to reference Carr NJ, Cecil TD, Mohamed F et al (2016) A consensus for classification and pathologic reporting of pseudomyxoma peritonei and associated appendiceal neoplasia: the results of the Peritoneal Surface Oncology Group International (PSOGI) modified Delphi process. Am J Surg Pathol 40:14–26PubMedCrossRef Carr NJ, Cecil TD, Mohamed F et al (2016) A consensus for classification and pathologic reporting of pseudomyxoma peritonei and associated appendiceal neoplasia: the results of the Peritoneal Surface Oncology Group International (PSOGI) modified Delphi process. Am J Surg Pathol 40:14–26PubMedCrossRef
58.
59.
go back to reference Ronnett BM, Zahn CM, Kurman RJ, Kass ME, Sugarbaker PH, Shmookler BM (1995) Disseminated peritoneal adenomucinosis and peritoneal mucinous carcinomatosis: a clinicopathologic analysis of 109 cases with emphasis on distinguishing pathologic features, site of origin, prognosis, and relationship to “pseudomyxoma peritonei.” Am J Surg Pathol 19:1390–1408PubMedCrossRef Ronnett BM, Zahn CM, Kurman RJ, Kass ME, Sugarbaker PH, Shmookler BM (1995) Disseminated peritoneal adenomucinosis and peritoneal mucinous carcinomatosis: a clinicopathologic analysis of 109 cases with emphasis on distinguishing pathologic features, site of origin, prognosis, and relationship to “pseudomyxoma peritonei.” Am J Surg Pathol 19:1390–1408PubMedCrossRef
60.
go back to reference Davison J, Choudry H, Pingpank J et al (2014) Clinicopathologic and molecular analysis of disseminated appendiceal mucinous neoplasms: identification of factors predicting survival and proposed criteria for a three-tiered assessment of tumor grade. Mod Pathol 27:1521–1539PubMedCrossRef Davison J, Choudry H, Pingpank J et al (2014) Clinicopathologic and molecular analysis of disseminated appendiceal mucinous neoplasms: identification of factors predicting survival and proposed criteria for a three-tiered assessment of tumor grade. Mod Pathol 27:1521–1539PubMedCrossRef
61.
go back to reference Marcotte E, Dubé P, Drolet P et al (2014) Hyperthermic intraperitoneal chemotherapy with oxaliplatin as treatment for peritoneal carcinomatosis arising from the appendix and pseudomyxoma peritonei: a survival analysis. World J Surg Oncol 12:332PubMedPubMedCentralCrossRef Marcotte E, Dubé P, Drolet P et al (2014) Hyperthermic intraperitoneal chemotherapy with oxaliplatin as treatment for peritoneal carcinomatosis arising from the appendix and pseudomyxoma peritonei: a survival analysis. World J Surg Oncol 12:332PubMedPubMedCentralCrossRef
62.
go back to reference Sulkin TV, O’Neill H, Amin AI, Moran B (2002) CT in pseudomyxoma peritonei: a review of 17 cases. Clin Radiol 57(7):608–613PubMedCrossRef Sulkin TV, O’Neill H, Amin AI, Moran B (2002) CT in pseudomyxoma peritonei: a review of 17 cases. Clin Radiol 57(7):608–613PubMedCrossRef
63.
go back to reference Gillion JF, Franco D, Chapuis O et al (2009) Appendiceal mucoceles, pseudomyxoma peritonei and appendiceal mucinous neoplasms: update on the contribution of imaging to choice of surgical approach. J Chir (Paris) 146(2):150–166PubMedCrossRef Gillion JF, Franco D, Chapuis O et al (2009) Appendiceal mucoceles, pseudomyxoma peritonei and appendiceal mucinous neoplasms: update on the contribution of imaging to choice of surgical approach. J Chir (Paris) 146(2):150–166PubMedCrossRef
65.
go back to reference Oei TN, Jagannathan JP, Ramaiya N, Ros PR (2010) Peritoneal sarcomatosis versus peritoneal carcinomatosis: imaging findings at MDCT. AJR Am J Roentgenol 195(3):229–235CrossRef Oei TN, Jagannathan JP, Ramaiya N, Ros PR (2010) Peritoneal sarcomatosis versus peritoneal carcinomatosis: imaging findings at MDCT. AJR Am J Roentgenol 195(3):229–235CrossRef
66.
go back to reference Burkill GJ, Badran M, Thomas JM (2003) Malignant gastrointestinal stromal tumor: distribution, imaging features, and pattern of metastatic spread. Radiology 226:527–532PubMedCrossRef Burkill GJ, Badran M, Thomas JM (2003) Malignant gastrointestinal stromal tumor: distribution, imaging features, and pattern of metastatic spread. Radiology 226:527–532PubMedCrossRef
67.
go back to reference O’Regan KN, Jagannathan J, Krajewski K et al (2011) Imaging of liposarcoma: classification, patterns of tumor recurrence, and response to treatment. AJR Am J Roentgenol 197(1):W37-43PubMedCrossRef O’Regan KN, Jagannathan J, Krajewski K et al (2011) Imaging of liposarcoma: classification, patterns of tumor recurrence, and response to treatment. AJR Am J Roentgenol 197(1):W37-43PubMedCrossRef
68.
69.
go back to reference Al-Dasuqi K, Irshaid L, Mathur M (2020) Radiologic-pathologic correlation of primary retroperitoneal neoplasms. Radiographics 40(6):1631–1657PubMedCrossRef Al-Dasuqi K, Irshaid L, Mathur M (2020) Radiologic-pathologic correlation of primary retroperitoneal neoplasms. Radiographics 40(6):1631–1657PubMedCrossRef
70.
go back to reference Katz SC, DeMatteo RP (2008) Gastrointestinal stromal tumors and leiomyosarcoma. J Surg Oncol 97:350–359PubMedCrossRef Katz SC, DeMatteo RP (2008) Gastrointestinal stromal tumors and leiomyosarcoma. J Surg Oncol 97:350–359PubMedCrossRef
73.
go back to reference Zhu M, Wu Z, Yang Z et al (2021) Non-Hodgkin’s lymphoma presenting as isolated peritoneal lymphomatosis: a case report and literature review. Front Oncol 11:719554PubMedPubMedCentralCrossRef Zhu M, Wu Z, Yang Z et al (2021) Non-Hodgkin’s lymphoma presenting as isolated peritoneal lymphomatosis: a case report and literature review. Front Oncol 11:719554PubMedPubMedCentralCrossRef
74.
go back to reference Horger M, Müller-Schimpfle M, Yirkin I, Wehrmann M, Claussen CD (2004) Extensive peritoneal and omental lymphomatosis with raised CA 125 mimicking carcinomatosis: CT and intraoperative findings. Br J Radiol 77:71–73PubMedCrossRef Horger M, Müller-Schimpfle M, Yirkin I, Wehrmann M, Claussen CD (2004) Extensive peritoneal and omental lymphomatosis with raised CA 125 mimicking carcinomatosis: CT and intraoperative findings. Br J Radiol 77:71–73PubMedCrossRef
75.
go back to reference Cabral FC, Krajewski KM, Kim KW, Ramaiya NH, Jagannathan JP (2013) Peritoneal lymphomatosis: CT and PET/CT findings and how to differentiate between carcinomatosis and sarcomatosis. Cancer Imaging 13(2):162–170PubMedPubMedCentralCrossRef Cabral FC, Krajewski KM, Kim KW, Ramaiya NH, Jagannathan JP (2013) Peritoneal lymphomatosis: CT and PET/CT findings and how to differentiate between carcinomatosis and sarcomatosis. Cancer Imaging 13(2):162–170PubMedPubMedCentralCrossRef
76.
go back to reference Karaosmanoglu D, Karcaaltincaba M, Oguz B, Akata D, Özmen M, Akhan O (2009) CT findings of lymphoma with peritoneal, omental and mesenteric involvement: peritoneal lymphomatosis. Eur J Radiol 71(2):313–317PubMedCrossRef Karaosmanoglu D, Karcaaltincaba M, Oguz B, Akata D, Özmen M, Akhan O (2009) CT findings of lymphoma with peritoneal, omental and mesenteric involvement: peritoneal lymphomatosis. Eur J Radiol 71(2):313–317PubMedCrossRef
77.
go back to reference Bellah R, Suzuki-Bordalo L, Brecher E, Ginsberg JP, Maris J, Pawel BR (2005) Desmoplastic small round cell tumor in the abdomen and pelvis: report of CT findings in 11 affected children and young adults. AJR Am J Roentgenol 184:1910–1914PubMedCrossRef Bellah R, Suzuki-Bordalo L, Brecher E, Ginsberg JP, Maris J, Pawel BR (2005) Desmoplastic small round cell tumor in the abdomen and pelvis: report of CT findings in 11 affected children and young adults. AJR Am J Roentgenol 184:1910–1914PubMedCrossRef
78.
go back to reference Pickhardt PJ, Fisher AJ, Balfe DM, Dehner LP, Huettner PC (1999) Desmoplastic small round cell tumor of the abdomen: radiologic-histopathologic correlation. Radiology 210:633–638PubMedCrossRef Pickhardt PJ, Fisher AJ, Balfe DM, Dehner LP, Huettner PC (1999) Desmoplastic small round cell tumor of the abdomen: radiologic-histopathologic correlation. Radiology 210:633–638PubMedCrossRef
79.
go back to reference Lae ME, Roche PC, Jin L, Lloyd RV, Nascimento AG (2002) Desmoplastic small round cell tumor: a clinicopathologic, immunohistochemical, and molecular study of 32 tumors. Am J Surg Pathol 26:823–835PubMedCrossRef Lae ME, Roche PC, Jin L, Lloyd RV, Nascimento AG (2002) Desmoplastic small round cell tumor: a clinicopathologic, immunohistochemical, and molecular study of 32 tumors. Am J Surg Pathol 26:823–835PubMedCrossRef
81.
go back to reference Lal DR, Su WT, Wolden SL, Loh KC, Modak S, La Quaglia MP (2005) Results of multimodal treatment for desmoplastic small round cell tumors. J Pediatr Surg 40:251–255PubMedCrossRef Lal DR, Su WT, Wolden SL, Loh KC, Modak S, La Quaglia MP (2005) Results of multimodal treatment for desmoplastic small round cell tumors. J Pediatr Surg 40:251–255PubMedCrossRef
82.
go back to reference Gani F, Goel U, Canner JK, Meyer CF, Johnston FM (2019) A national analysis of patterns of care and outcomes for adults diagnosed with desmoplastic small round cell tumors in the United States. J Surg Oncol 119:880–886PubMedCrossRef Gani F, Goel U, Canner JK, Meyer CF, Johnston FM (2019) A national analysis of patterns of care and outcomes for adults diagnosed with desmoplastic small round cell tumors in the United States. J Surg Oncol 119:880–886PubMedCrossRef
83.
go back to reference Papadatos D, Taourel P, Bret PM (1996) CT of leiomyomatosis peritonealis disseminata mimicking peritoneal carcinomatosis. AJR Am J Roentgenol 167(2):475–476PubMedCrossRef Papadatos D, Taourel P, Bret PM (1996) CT of leiomyomatosis peritonealis disseminata mimicking peritoneal carcinomatosis. AJR Am J Roentgenol 167(2):475–476PubMedCrossRef
84.
go back to reference Lu B, Xu J, Pan Z (2016) Iatrogenic parasitic leiomyoma and leiomyomatosis peritonealis disseminata following uterine morcellation. J Obstet Gynaecol Res 42(8):990–999PubMedCrossRef Lu B, Xu J, Pan Z (2016) Iatrogenic parasitic leiomyoma and leiomyomatosis peritonealis disseminata following uterine morcellation. J Obstet Gynaecol Res 42(8):990–999PubMedCrossRef
85.
go back to reference Chen X, Liu H, Shi H, Fan Q, Sun D, Lang J (2021) Leiomyomatosis peritonealis disseminata following laparoscopic surgery with uncontained morcellation: 13 cases from one institution. Front Surg 8:788749PubMedPubMedCentralCrossRef Chen X, Liu H, Shi H, Fan Q, Sun D, Lang J (2021) Leiomyomatosis peritonealis disseminata following laparoscopic surgery with uncontained morcellation: 13 cases from one institution. Front Surg 8:788749PubMedPubMedCentralCrossRef
86.
go back to reference Nguyen GK (1993) Disseminated leiomyomatosis peritonealis: report of a case in a postmenopausal woman. Can J Surg 36:46–48PubMed Nguyen GK (1993) Disseminated leiomyomatosis peritonealis: report of a case in a postmenopausal woman. Can J Surg 36:46–48PubMed
87.
go back to reference Boavida Ferreira J, Cabrera R, Santos F et al (2022) Benign metastasizing leiomyomatosis to the skin and lungs, intravenous leiomyomatosis, and leiomyomatosis peritonealis disseminata: a series of five cases. Oncologist 27(1):e89–e98PubMedPubMedCentralCrossRef Boavida Ferreira J, Cabrera R, Santos F et al (2022) Benign metastasizing leiomyomatosis to the skin and lungs, intravenous leiomyomatosis, and leiomyomatosis peritonealis disseminata: a series of five cases. Oncologist 27(1):e89–e98PubMedPubMedCentralCrossRef
88.
go back to reference Randrianjafisamindrakotroka NS, Baldauf JJ, Philippe E, Ritter J, Collin D, Kaemmerlen C (1995) Leiomyomatosis peritonealis disseminata: report on two cases and differential diagnosis with peritoneal metastases of a low-grade stromal sarcoma of the ovary. Pathol Res Pract 191:1252–1257PubMedCrossRef Randrianjafisamindrakotroka NS, Baldauf JJ, Philippe E, Ritter J, Collin D, Kaemmerlen C (1995) Leiomyomatosis peritonealis disseminata: report on two cases and differential diagnosis with peritoneal metastases of a low-grade stromal sarcoma of the ovary. Pathol Res Pract 191:1252–1257PubMedCrossRef
89.
go back to reference Heinig J, Neff A, Cirkel U, Klockenbusch W (2003) Recurrent leiomyomatosis peritonealis disseminata after hysterectomy and bilateral salpingo-oophorectomy during combined hormone replacement therapy. Eur J Obstet Gynecol Reprod Biol 111:216–218PubMedCrossRef Heinig J, Neff A, Cirkel U, Klockenbusch W (2003) Recurrent leiomyomatosis peritonealis disseminata after hysterectomy and bilateral salpingo-oophorectomy during combined hormone replacement therapy. Eur J Obstet Gynecol Reprod Biol 111:216–218PubMedCrossRef
90.
go back to reference Fulcher AS, Szucs RA (1998) Leiomyomatosis peritonealis disseminata complicated by sarcomatous transformation and ovarian torsion: presentation of two cases and review of the literature. Abdom Imaging 23:640–644PubMedCrossRef Fulcher AS, Szucs RA (1998) Leiomyomatosis peritonealis disseminata complicated by sarcomatous transformation and ovarian torsion: presentation of two cases and review of the literature. Abdom Imaging 23:640–644PubMedCrossRef
91.
go back to reference Vázquez Muñoz E, Gómez-Cerezo J, Atienza Saura M, Vázquez Rodriguez JJ (2004) Computed tomography findings of peritoneal tuberculosis: systematic review of seven patients diagnosed in 6 years (1996–2001). Clin Imaging 28:340–343PubMedCrossRef Vázquez Muñoz E, Gómez-Cerezo J, Atienza Saura M, Vázquez Rodriguez JJ (2004) Computed tomography findings of peritoneal tuberculosis: systematic review of seven patients diagnosed in 6 years (1996–2001). Clin Imaging 28:340–343PubMedCrossRef
92.
go back to reference Da Rocha EL, Pedrassa BC, Bormann RL, Kierszenbaum ML, Torres LR, D’Ippolito G (2015) Abdominal tuberculosis: a radiological review with emphasis on computed tomography and magnetic resonance imaging findings. Radiol Bras 48(3):181–191PubMedPubMedCentralCrossRef Da Rocha EL, Pedrassa BC, Bormann RL, Kierszenbaum ML, Torres LR, D’Ippolito G (2015) Abdominal tuberculosis: a radiological review with emphasis on computed tomography and magnetic resonance imaging findings. Radiol Bras 48(3):181–191PubMedPubMedCentralCrossRef
93.
94.
go back to reference Wu DC, Averbukh LD, Wu GY (2019) Diagnostic and therapeutic strategies for peritoneal tuberculosis: a review. J Clin Transl Hepatol 7(2):140–148PubMedPubMedCentral Wu DC, Averbukh LD, Wu GY (2019) Diagnostic and therapeutic strategies for peritoneal tuberculosis: a review. J Clin Transl Hepatol 7(2):140–148PubMedPubMedCentral
95.
go back to reference Levy AD, Rimola J, Mehrotra AK, Sobin LH (2006) Benign fibrous tumors and tumorlike lesions of the mesentery: radiologic-pathologic correlation. Radiographics 26:245–264PubMedCrossRef Levy AD, Rimola J, Mehrotra AK, Sobin LH (2006) Benign fibrous tumors and tumorlike lesions of the mesentery: radiologic-pathologic correlation. Radiographics 26:245–264PubMedCrossRef
97.
go back to reference Kim SW, Shin HC, Kim IY, Baek MJ, Cho HD (2009) Foreign body granulomas simulating recurrent tumors in patients following colorectal surgery for carcinoma: a report of two cases. Korean J Radiol 10(3):313–318PubMedPubMedCentralCrossRef Kim SW, Shin HC, Kim IY, Baek MJ, Cho HD (2009) Foreign body granulomas simulating recurrent tumors in patients following colorectal surgery for carcinoma: a report of two cases. Korean J Radiol 10(3):313–318PubMedPubMedCentralCrossRef
98.
go back to reference Audollent R, Eveno C, Dohan A et al (2015) Pitfalls and mimickers on 18F-FDG-PET/CT in peritoneal carcinomatosis from colorectal cancer: an analysis from 37 patients. J Visc Surg 152(5):285–291PubMedCrossRef Audollent R, Eveno C, Dohan A et al (2015) Pitfalls and mimickers on 18F-FDG-PET/CT in peritoneal carcinomatosis from colorectal cancer: an analysis from 37 patients. J Visc Surg 152(5):285–291PubMedCrossRef
99.
go back to reference Suh J, Kang HJ, Kim SH (2020) Differentiation of intra-abdominal desmoid tumor from peritoneal seeding based on CT and/or 18F-FDG PET-CT in patients with history of cancer surgery. Abdom Radiol (NY) 45(9):2647–2655PubMedCrossRef Suh J, Kang HJ, Kim SH (2020) Differentiation of intra-abdominal desmoid tumor from peritoneal seeding based on CT and/or 18F-FDG PET-CT in patients with history of cancer surgery. Abdom Radiol (NY) 45(9):2647–2655PubMedCrossRef
100.
go back to reference Siemion K, Reszec-Gielazyn J, Kisluk J, Roszkowiak L, Zak J, Korzynska A (2022) What do we know about inflammatory myofibroblastic tumors? A systematic review. Adv Med Sci 67(1):129–138PubMedCrossRef Siemion K, Reszec-Gielazyn J, Kisluk J, Roszkowiak L, Zak J, Korzynska A (2022) What do we know about inflammatory myofibroblastic tumors? A systematic review. Adv Med Sci 67(1):129–138PubMedCrossRef
101.
go back to reference Narla LD, Newman B, Spottswood SS, Narla S, Kolli R (2003) Inflammatory pseudotumor. Radiographics 23:719–729PubMedCrossRef Narla LD, Newman B, Spottswood SS, Narla S, Kolli R (2003) Inflammatory pseudotumor. Radiographics 23:719–729PubMedCrossRef
102.
go back to reference Cantera JE, Alfaro MP, Rafart DC et al (2015) Inflammatory myofibroblastic tumours: a pictorial review. Insights Imaging 6:85–96PubMedCrossRef Cantera JE, Alfaro MP, Rafart DC et al (2015) Inflammatory myofibroblastic tumours: a pictorial review. Insights Imaging 6:85–96PubMedCrossRef
103.
go back to reference Chougule A, Bal A (2017) IgG4-related inflammatory pseudotumor: a systematic review of histopathological features of reported cases. Mod Rheumatol 27(2):320–325PubMedCrossRef Chougule A, Bal A (2017) IgG4-related inflammatory pseudotumor: a systematic review of histopathological features of reported cases. Mod Rheumatol 27(2):320–325PubMedCrossRef
104.
go back to reference Patnana M, Sevrukov AB, Elsayes KM, Viswanathan C, Lubner M, Menias CO (2012) Inflammatory pseudotumor: the great mimicker. AJR Am J Roentgenol 198:W217–W227PubMedCrossRef Patnana M, Sevrukov AB, Elsayes KM, Viswanathan C, Lubner M, Menias CO (2012) Inflammatory pseudotumor: the great mimicker. AJR Am J Roentgenol 198:W217–W227PubMedCrossRef
105.
go back to reference Woodward PJ, Sohaey R, Mezzetti TP Jr (2001) Endometriosis: radiologic-pathologic correlation. Radiographics 21:193–216PubMedCrossRef Woodward PJ, Sohaey R, Mezzetti TP Jr (2001) Endometriosis: radiologic-pathologic correlation. Radiographics 21:193–216PubMedCrossRef
106.
go back to reference Bazot M, Darai E, Hourani R et al (2004) Deep pelvic endometriosis: MR imaging for diagnosis and prediction of extension of disease. Radiology 232:379–389PubMedCrossRef Bazot M, Darai E, Hourani R et al (2004) Deep pelvic endometriosis: MR imaging for diagnosis and prediction of extension of disease. Radiology 232:379–389PubMedCrossRef
108.
go back to reference Moon C, Choi YJ, Kim EY et al (2013) Combined intrathoracic and intraperitoneal splenosis after splenic injury: case report and review of the literature. Tuberc Respir Dis 74:134–139CrossRef Moon C, Choi YJ, Kim EY et al (2013) Combined intrathoracic and intraperitoneal splenosis after splenic injury: case report and review of the literature. Tuberc Respir Dis 74:134–139CrossRef
Metadata
Title
Primary and secondary tumors of the peritoneum: key imaging features and differential diagnosis with surgical and pathological correlation
Authors
Javier Miguez González
Francesc Calaf Forn
Laura Pelegrí Martínez
Pilar Lozano Arranz
Rafael Oliveira Caiafa
Jordi Català Forteza
Lina Maria Palacio Arteaga
Ferrán Losa Gaspà
Isabel Ramos Bernadó
Pedro Barrios Sánchez
Juan Ramón Ayuso Colella
Publication date
01-12-2023
Publisher
Springer Vienna
Published in
Insights into Imaging / Issue 1/2023
Electronic ISSN: 1869-4101
DOI
https://doi.org/10.1186/s13244-023-01417-6

Other articles of this Issue 1/2023

Insights into Imaging 1/2023 Go to the issue