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Published in: Journal of Diabetes & Metabolic Disorders 2/2018

01-12-2018 | Review Article

Menopause and metabolic syndrome in the Middle East countries; a systematic review and meta-analysis study

Authors: Ozra Tabatabaei-Malazy, Shirin Djalalinia, Hamid Asayesh, Yalda Shakori, Mohammad Esmaeili Abdar, Morteza Mansourian, Armita Mahdavi Gorabi, Mehdi Noroozi, Mostafa Qorbani

Published in: Journal of Diabetes & Metabolic Disorders | Issue 2/2018

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Abstract

Introduction

Metabolic syndrome (MetS) prevalence that is associated with increasing risk of diabetes and cardiovascular diseases (CVD) has accelerated with age. Since, menopause is known as a partial cause of CVD accelartion with againg among women, determining the prevalence of MetS is important in this condition. We aimed to assess critically the prevalence rate of MetS among menopaused women in the Middle East Countries in this systematic review meta-analysis study.

Methods & Materials

International webdata bases including Scopus, ISI web of Science and PubMed were systematically searched using Medical Subject Headings terms from January 2000 to February 2017. We included all cross-sectional conducted in the Middle East that reported prevalence of MetS in menopause status regardless of MetS definition. Quality assessment was considered for each included study. The pooled prevalence of MetS based on the Adult Treatment Panel III (ATP III) was estimated using random effect method due to between-study heterogeneity by STATA software, version 11.0 (StataCorp, USA).

Results

Within 60 studies, 21 and 17 studies were included in qualitative synthesis and meta-analysis respectively. The prevalence of MetS among menopaused women was estimated 54.87% (95% CI: 53.76–55.97) in the Middle East countries. In sub-group analysis based on country the prevalence rate of MetS in Iran and Turkey was estimated 58.78% (95% CI: 57.54–60.02), and 39.02% (95% CI: 36.57–41.47), respectively.

Conclusions

MetS was highly prevalent as an alarming sign among menopaused women in the Middle East countries. Thus, it is an emergency requirement to promote healthy lifestyle. Also, early detection and treatment of women who reach menopause and are at great risk of developing MetS is necessary for prevention of diabetes and CVD in the region.
Literature
1.
go back to reference National cholesterol education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III): third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adult final report. Circulation 2002; 106:3143–3421. National cholesterol education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III): third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adult final report. Circulation 2002; 106:3143–3421.
2.
go back to reference Alberti KG, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA, Fruchart JC, James WP, Loria CM, Smith SC Jr, International Diabetes Federation Task Force on Epidemiology and Prevention., Hational Heart, Lung, and Blood Institute., American Heart Association., World Heart Federation., International Atherosclerosis Society., International Association for the Study of Obesity.; International diabetes federation task force on epidemiology and prevention; Hational heart, lung, and blood institute; American Heart Association; world heart federation; international atherosclerosis society; International Association for the Study of obesity. Harmonizing the metabolic syndrome: a joint interim statement of the international diabetes federation task force on epidemiology and prevention; National Heart, Lung, and Blood Institute; American Heart Association; world heart federation; international atherosclerosis society; and International Association for the Study of obesity. Circulation 2009;120(16):1640–5. https://doi.org/10.1161/CIRCULATIONAHA.109.192644. Alberti KG, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA, Fruchart JC, James WP, Loria CM, Smith SC Jr, International Diabetes Federation Task Force on Epidemiology and Prevention., Hational Heart, Lung, and Blood Institute., American Heart Association., World Heart Federation., International Atherosclerosis Society., International Association for the Study of Obesity.; International diabetes federation task force on epidemiology and prevention; Hational heart, lung, and blood institute; American Heart Association; world heart federation; international atherosclerosis society; International Association for the Study of obesity. Harmonizing the metabolic syndrome: a joint interim statement of the international diabetes federation task force on epidemiology and prevention; National Heart, Lung, and Blood Institute; American Heart Association; world heart federation; international atherosclerosis society; and International Association for the Study of obesity. Circulation 2009;120(16):1640–5. https://​doi.​org/​10.​1161/​CIRCULATIONAHA.​109.​192644.​
3.
go back to reference Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults: findings from the third National Health and nutrition examination survey. JAMA. 2002;287(3):356–9.CrossRefPubMed Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults: findings from the third National Health and nutrition examination survey. JAMA. 2002;287(3):356–9.CrossRefPubMed
5.
go back to reference Meigs JB, Nathan DM, Wolfsdorf JI, Mulder JE. The metabolic syndrome (insulin resistance syndrome or syndrome X). Available at: www.UpToDate.com. Last updated: Jan 13, 2017. Meigs JB, Nathan DM, Wolfsdorf JI, Mulder JE. The metabolic syndrome (insulin resistance syndrome or syndrome X). Available at: www.​UpToDate.​com. Last updated: Jan 13, 2017.
7.
go back to reference McNeill AM, Rosamond WD, Girman CJ, et al. The metabolic syndrome and 11-year risk of incident cardiovascular disease in the atherosclerosis risk in communities study. Diabetes Care. 2005;28:385–90.CrossRefPubMed McNeill AM, Rosamond WD, Girman CJ, et al. The metabolic syndrome and 11-year risk of incident cardiovascular disease in the atherosclerosis risk in communities study. Diabetes Care. 2005;28:385–90.CrossRefPubMed
11.
go back to reference Amirkalali B, Fakhrzadeh H, Sharifi F, Kelishadi R, Zamani F, Asayesh H, et al. Prevalence of metabolic syndrome and its components in the Iranian adult population: a systematic review and meta-analysis. Iran Red Crescent Med J. 2015;17(12):e24723. https://doi.org/10.5812/ircmj.24723. Amirkalali B, Fakhrzadeh H, Sharifi F, Kelishadi R, Zamani F, Asayesh H, et al. Prevalence of metabolic syndrome and its components in the Iranian adult population: a systematic review and meta-analysis. Iran Red Crescent Med J. 2015;17(12):e24723. https://​doi.​org/​10.​5812/​ircmj.​24723.​
12.
go back to reference Mendes KG, Theodoro H, Rodrigues AD, Olinto MT. Prevalence of metabolic syndrome and its components in the menopausal transition: a systematic review. Cad Saude Publica. 2012;28(8):1423–37.CrossRefPubMed Mendes KG, Theodoro H, Rodrigues AD, Olinto MT. Prevalence of metabolic syndrome and its components in the menopausal transition: a systematic review. Cad Saude Publica. 2012;28(8):1423–37.CrossRefPubMed
14.
16.
18.
go back to reference Ainy E, Mirmiran P, Zahedi Asl S, Azizi F. Prevalence of metabolic syndrome during menopausal transition Tehranian women: Tehran lipid and glucose study (TLGS). Maturitas. 2007;58(2):150–5.CrossRefPubMed Ainy E, Mirmiran P, Zahedi Asl S, Azizi F. Prevalence of metabolic syndrome during menopausal transition Tehranian women: Tehran lipid and glucose study (TLGS). Maturitas. 2007;58(2):150–5.CrossRefPubMed
22.
go back to reference Akbulut G. Does the prevalence of metabolic syndrome in pre- and post-menopausal women differ by the ATP III and IDF criteria? Turkiye Klinikleri J Med Sci. 2011;31(6):1463–70.CrossRef Akbulut G. Does the prevalence of metabolic syndrome in pre- and post-menopausal women differ by the ATP III and IDF criteria? Turkiye Klinikleri J Med Sci. 2011;31(6):1463–70.CrossRef
28.
go back to reference Sarrafzadegan N, Khosravi-Boroujeni H, Esmaillzadeh A, Sadeghi M, Rafieian-Kopaei M, Asgary S. The association between hypertriglyceridemic waist phenotype, menopause, and cardiovascular risk factors Arch Iran Med 2013;16(3):161–166. 013163/AIM.008. Sarrafzadegan N, Khosravi-Boroujeni H, Esmaillzadeh A, Sadeghi M, Rafieian-Kopaei M, Asgary S. The association between hypertriglyceridemic waist phenotype, menopause, and cardiovascular risk factors Arch Iran Med 2013;16(3):161–166. 013163/AIM.008.
34.
go back to reference Namazi Shabestari A, Asadi M, Jouyandeh Z, Qorbani M, Kelishadi R. Association of lipid accumulation product with cardio-metabolic risk factors in postmenopausal women. Acta Med Iran. 2016;54:370–5.PubMed Namazi Shabestari A, Asadi M, Jouyandeh Z, Qorbani M, Kelishadi R. Association of lipid accumulation product with cardio-metabolic risk factors in postmenopausal women. Acta Med Iran. 2016;54:370–5.PubMed
36.
go back to reference Indhavivadhana S, Rattanachaiyanont M, Wongvananurak T, Kanboon M, Techatraisak K, Leerasiri P, et al. Predictors for metabolic syndrome in perimenopausal and postmenopausal Thai women. Climacteric. 2011;14:58–65. Indhavivadhana S, Rattanachaiyanont M, Wongvananurak T, Kanboon M, Techatraisak K, Leerasiri P, et al. Predictors for metabolic syndrome in perimenopausal and postmenopausal Thai women. Climacteric. 2011;14:58–65.
45.
go back to reference Delavari A, Forouzanfar MH, Alikhani S, Sharifian A, Kelishadi R. First nationwide study of the prevalence of the metabolic syndrome and optimal cutoff points of waist circumference in the Middle East: the national survey of risk factors for noncommunicable diseases of Iran. Diabetes Care. 2009;32(6):1092–7. https://doi.org/10.2337/dc08-1800.CrossRefPubMedPubMedCentral Delavari A, Forouzanfar MH, Alikhani S, Sharifian A, Kelishadi R. First nationwide study of the prevalence of the metabolic syndrome and optimal cutoff points of waist circumference in the Middle East: the national survey of risk factors for noncommunicable diseases of Iran. Diabetes Care. 2009;32(6):1092–7. https://​doi.​org/​10.​2337/​dc08-1800.CrossRefPubMedPubMedCentral
46.
go back to reference Hajian-Tilaki KO, Heidari B. Prevalence of obesity, central obesity and the associated factors in urban population aged 20–70 years, in the north of Iran: a population-based study and regression approach. Obes Rev. 2007;8(1):3–10.CrossRefPubMed Hajian-Tilaki KO, Heidari B. Prevalence of obesity, central obesity and the associated factors in urban population aged 20–70 years, in the north of Iran: a population-based study and regression approach. Obes Rev. 2007;8(1):3–10.CrossRefPubMed
47.
go back to reference Dalvand S, Niksima SH, Meshkani R, Ghanei Gheshlagh R, Sadegh-Nejadi S, Kooti W, et al. Prevalence of metabolic syndrome among Iranian population: a systematic review and meta-analysis. Iran J Public Health. 2017;46:456–67. Dalvand S, Niksima SH, Meshkani R, Ghanei Gheshlagh R, Sadegh-Nejadi S, Kooti W, et al. Prevalence of metabolic syndrome among Iranian population: a systematic review and meta-analysis. Iran J Public Health. 2017;46:456–67.
48.
go back to reference Tabatabaei-Malazy O, Qorbani M, Samavat T, Sharifi F, Larijani B, Fakhrzadeh H. Prevalence of dyslipidemia in Iran: a systematic review and meta-analysis study. Int J Prev Med. 2014;5:373–93.PubMedPubMedCentral Tabatabaei-Malazy O, Qorbani M, Samavat T, Sharifi F, Larijani B, Fakhrzadeh H. Prevalence of dyslipidemia in Iran: a systematic review and meta-analysis study. Int J Prev Med. 2014;5:373–93.PubMedPubMedCentral
49.
go back to reference Qorbani M, Tabatabaei-Malazy O, Kelishadi R, Larijani B. Mean serum lipid levels in Iranian adult populations: a systematic review and meta-analysis. Clin Lipidol. 2015;10(5):449–64.CrossRef Qorbani M, Tabatabaei-Malazy O, Kelishadi R, Larijani B. Mean serum lipid levels in Iranian adult populations: a systematic review and meta-analysis. Clin Lipidol. 2015;10(5):449–64.CrossRef
51.
go back to reference Mirzaei M, Moayedallaie S, Jabbari L, Mohammadi M. Prevalence of hypertension in Iran 1980-2012: a systematic review. J Tehran heart Cent. 2016;11:159–67.PubMedPubMedCentral Mirzaei M, Moayedallaie S, Jabbari L, Mohammadi M. Prevalence of hypertension in Iran 1980-2012: a systematic review. J Tehran heart Cent. 2016;11:159–67.PubMedPubMedCentral
53.
go back to reference Mabry RM, Reeves MM, Eakin EG, Owen N. Gender differences in prevalence of the metabolic syndrome in gulf cooperation council countries: a systematic review. Diabet Med. 2010;27(5):593–7.CrossRefPubMed Mabry RM, Reeves MM, Eakin EG, Owen N. Gender differences in prevalence of the metabolic syndrome in gulf cooperation council countries: a systematic review. Diabet Med. 2010;27(5):593–7.CrossRefPubMed
Metadata
Title
Menopause and metabolic syndrome in the Middle East countries; a systematic review and meta-analysis study
Authors
Ozra Tabatabaei-Malazy
Shirin Djalalinia
Hamid Asayesh
Yalda Shakori
Mohammad Esmaeili Abdar
Morteza Mansourian
Armita Mahdavi Gorabi
Mehdi Noroozi
Mostafa Qorbani
Publication date
01-12-2018
Publisher
Springer International Publishing
Published in
Journal of Diabetes & Metabolic Disorders / Issue 2/2018
Electronic ISSN: 2251-6581
DOI
https://doi.org/10.1007/s40200-018-0375-1

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