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Published in: BMC Geriatrics 1/2013

Open Access 01-12-2013 | Study protocol

Medication management for people with dementia in primary care: description of implementation in the DelpHi study

Authors: Thomas Fiß, Jochen René Thyrian, Diana Wucherer, Grit Aßmann, Ingo Kilimann, Stefan J Teipel, Wolfgang Hoffmann

Published in: BMC Geriatrics | Issue 1/2013

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Abstract

Background

As the population ages, the relative and absolute number of age-associated diseases such as dementia will increase. Evaluation of the suitability and intake of medication and pharmacological treatment is an important aspect of care for people with dementia, especially if they live at home. Regular medication reviews and systematic cooperation between physicians and pharmacists are not common in routine care. Medication management (MM), based on such a comprehensive home medication review could help to reduce drug-related problems and costs. The present article presents a medication management specifically for the application in the ambulatory setting and describes its implementation as part of a larger trial.

Methods/design

A home medication review (HMR) and MM is implemented as part of the DelpHi study, a population based prospective, cluster-randomized controlled intervention study to test the efficacy and efficiency of the implementation of a collaborative care model in primary care.
Participants: people with dementia (PWD) and their caregivers are recruited by the patient’s general practitioner. Inclusion criteria are a positive screening result for dementia, living at home and regular intake of drugs. PWD are asked to specify their regular pharmacy which is asked to participate in the study, too.
Intervention: a comprehensive HMR is conducted as computer-assisted personal interview by specifically qualified Dementia Care Manager (DCM) at the people’s home. It includes detailed information about drugs taken, their storage, administration, adherence and adverse events. The MM is conducted in cooperation between DCM, pharmacist and general practitioner and consists of a pharmaceutical evaluation, pharmaceutical recommendations and their application. Pharmacists are trained and provided with regularly updated information. The MM is designed to give information and recommendations concerning antidementia drugs, occurrence of drug related problems, intake of anticholinergic drugs, potentially clinically relevant drug-drug-interactions, adverse drug events and medication adherence.

Discussion

The DelpHi-approach for medication management employs comprehensive instruments and procedures in the primary care setting under routine care conditions, and this approach should be useful in improving pharmacotherapy as part of the comprehensive treatment and care for people with dementia.

Trial registration

The trial is registered at ClinicalTrials.gov, number NCT01401582.
Appendix
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Literature
1.
go back to reference Siewert U, Fendrich K, Doblhammer-Reiter G, Scholz RD, Schuff-Werner P, Hoffmann W: Health care consequences of demographic changes in Mecklenburg-West Pomerania: projected case numbers for age-related diseases up to the year 2020, based on the study of health in Pomerania (SHIP). Dtsch Arztebl Int. 2010, 107: 328-334.PubMedPubMedCentral Siewert U, Fendrich K, Doblhammer-Reiter G, Scholz RD, Schuff-Werner P, Hoffmann W: Health care consequences of demographic changes in Mecklenburg-West Pomerania: projected case numbers for age-related diseases up to the year 2020, based on the study of health in Pomerania (SHIP). Dtsch Arztebl Int. 2010, 107: 328-334.PubMedPubMedCentral
2.
go back to reference Thyrian JR, Dreier A, Fendrich K, Lueke S, Hoffmann W: Demenzerkrankungen–Wirksame Konzepte gesucht. Deutsches Ärzteblatt. 2011, 108: A1954-A1956. Thyrian JR, Dreier A, Fendrich K, Lueke S, Hoffmann W: Demenzerkrankungen–Wirksame Konzepte gesucht. Deutsches Ärzteblatt. 2011, 108: A1954-A1956.
4.
go back to reference Campbell N, Boustani M, Limbil T, Ott C, Fox C, Maidment I, et al: The cognitive impact of anticholinergics: a clinical review. Clin Interv Aging. 2009, 4: 225-233.PubMedPubMedCentral Campbell N, Boustani M, Limbil T, Ott C, Fox C, Maidment I, et al: The cognitive impact of anticholinergics: a clinical review. Clin Interv Aging. 2009, 4: 225-233.PubMedPubMedCentral
5.
go back to reference Fortin MP, Rouch I, Dauphinot V, Gedeon C, Genthon S, Bonnefoy M, et al: Effects of anticholinergic drugs on verbal episodic memory function in the elderly: a retrospective, cross-sectional study. Drugs Aging. 2011, 28: 195-204. 10.2165/11586580-000000000-00000.CrossRefPubMed Fortin MP, Rouch I, Dauphinot V, Gedeon C, Genthon S, Bonnefoy M, et al: Effects of anticholinergic drugs on verbal episodic memory function in the elderly: a retrospective, cross-sectional study. Drugs Aging. 2011, 28: 195-204. 10.2165/11586580-000000000-00000.CrossRefPubMed
6.
go back to reference Sela-Katz P, Rabinowitz I, Shugaev I, Shigorina G: Basic knowledge of the medication regimen correlates with performance on cognitive function tests and diagnosis of dementia in elderly patients referred to a geriatric assessment unit. Gerontology. 2010, 56: 491-495. 10.1159/000304738.CrossRefPubMed Sela-Katz P, Rabinowitz I, Shugaev I, Shigorina G: Basic knowledge of the medication regimen correlates with performance on cognitive function tests and diagnosis of dementia in elderly patients referred to a geriatric assessment unit. Gerontology. 2010, 56: 491-495. 10.1159/000304738.CrossRefPubMed
7.
go back to reference Rottenkolber D, Schmiedl S, Rottenkolber M, Farker K, Salje K, Mueller S, et al: Adverse drug reactions in Germany: direct costs of internal medicine hospitalizations. Pharmacoepidemiol Drug Saf. 2011, 20: 626-634. 10.1002/pds.2118.CrossRefPubMed Rottenkolber D, Schmiedl S, Rottenkolber M, Farker K, Salje K, Mueller S, et al: Adverse drug reactions in Germany: direct costs of internal medicine hospitalizations. Pharmacoepidemiol Drug Saf. 2011, 20: 626-634. 10.1002/pds.2118.CrossRefPubMed
8.
go back to reference Schneeweiss S, Hasford J, Gottler M, Hoffmann A, Riethling AK, Avorn J: Admissions caused by adverse drug events to internal medicine and emergency departments in hospitals: a longitudinal population-based study. Eur J Clin Pharmacol. 2002, 58: 285-291. 10.1007/s00228-002-0467-0.CrossRefPubMed Schneeweiss S, Hasford J, Gottler M, Hoffmann A, Riethling AK, Avorn J: Admissions caused by adverse drug events to internal medicine and emergency departments in hospitals: a longitudinal population-based study. Eur J Clin Pharmacol. 2002, 58: 285-291. 10.1007/s00228-002-0467-0.CrossRefPubMed
9.
go back to reference Schaefer M: Discussing basic principles for a coding system of drug-related problems: the case of PI-Doc. Pharm World Sci. 2002, 24: 120-127. 10.1023/A:1019543029936.CrossRefPubMed Schaefer M: Discussing basic principles for a coding system of drug-related problems: the case of PI-Doc. Pharm World Sci. 2002, 24: 120-127. 10.1023/A:1019543029936.CrossRefPubMed
10.
go back to reference Cancelli I, Beltrame M, Gigli GL, Valente M: Drugs with anticholinergic properties: cognitive and neuropsychiatric side-effects in elderly patients. Neurol Sci. 2009, 30: 87-92. 10.1007/s10072-009-0033-y.CrossRefPubMed Cancelli I, Beltrame M, Gigli GL, Valente M: Drugs with anticholinergic properties: cognitive and neuropsychiatric side-effects in elderly patients. Neurol Sci. 2009, 30: 87-92. 10.1007/s10072-009-0033-y.CrossRefPubMed
11.
go back to reference Cancelli I, Beltrame M, D’Anna L, Gigli GL, Valente M: Drugs with anticholinergic properties: a potential risk factor for psychosis onset in Alzheimer’s disease?. Expert Opin Drug Saf. 2009, 8: 549-557. 10.1517/14740330903099636.CrossRefPubMed Cancelli I, Beltrame M, D’Anna L, Gigli GL, Valente M: Drugs with anticholinergic properties: a potential risk factor for psychosis onset in Alzheimer’s disease?. Expert Opin Drug Saf. 2009, 8: 549-557. 10.1517/14740330903099636.CrossRefPubMed
12.
go back to reference Carriere I, Fourrier-Reglat A, Dartigues JF, Rouaud O, Pasquier F, Ritchie K, et al: Drugs with anticholinergic properties, cognitive decline, and dementia in an elderly general population: the 3-city study. Arch Intern Med. 2009, 169: 1317-1324. 10.1001/archinternmed.2009.229.CrossRefPubMedPubMedCentral Carriere I, Fourrier-Reglat A, Dartigues JF, Rouaud O, Pasquier F, Ritchie K, et al: Drugs with anticholinergic properties, cognitive decline, and dementia in an elderly general population: the 3-city study. Arch Intern Med. 2009, 169: 1317-1324. 10.1001/archinternmed.2009.229.CrossRefPubMedPubMedCentral
13.
go back to reference Giron MS, Wang HX, Bernsten C, Thorslund M, Winblad B, Fastbom J: The appropriateness of drug use in an older nondemented and demented population. J Am Geriatr Soc. 2001, 49: 277-283. 10.1046/j.1532-5415.2001.4930277.x.CrossRefPubMed Giron MS, Wang HX, Bernsten C, Thorslund M, Winblad B, Fastbom J: The appropriateness of drug use in an older nondemented and demented population. J Am Geriatr Soc. 2001, 49: 277-283. 10.1046/j.1532-5415.2001.4930277.x.CrossRefPubMed
14.
go back to reference van der Velde N, Stricker BH, Pols HA, van der Cammen TJ: Risk of falls after withdrawal of fall-risk-increasing drugs: a prospective cohort study. Br J Clin Pharmacol. 2007, 63: 232-237. 10.1111/j.1365-2125.2006.02736.x.CrossRefPubMed van der Velde N, Stricker BH, Pols HA, van der Cammen TJ: Risk of falls after withdrawal of fall-risk-increasing drugs: a prospective cohort study. Br J Clin Pharmacol. 2007, 63: 232-237. 10.1111/j.1365-2125.2006.02736.x.CrossRefPubMed
15.
go back to reference Hoffmann W, van den Berg N, Thyrian JR, Fiss T: Frequency and determinants of potential drug-drug interactions in an elderly population receiving regular home visits by GPs–results of the home medication review in the AGnES-studies. Pharmacoepidemiol Drug Saf. 2011, 20 (12): 1311-1318. 10.1002/pds.2224.CrossRefPubMed Hoffmann W, van den Berg N, Thyrian JR, Fiss T: Frequency and determinants of potential drug-drug interactions in an elderly population receiving regular home visits by GPs–results of the home medication review in the AGnES-studies. Pharmacoepidemiol Drug Saf. 2011, 20 (12): 1311-1318. 10.1002/pds.2224.CrossRefPubMed
16.
go back to reference Arlt S, Lindner R, Rosler A, Von Renteln-Kruse W: Adherence to medication in patients with dementia: predictors and strategies for improvement. Drugs Aging. 2008, 25: 1033-1047. 10.2165/0002512-200825120-00005.CrossRefPubMed Arlt S, Lindner R, Rosler A, Von Renteln-Kruse W: Adherence to medication in patients with dementia: predictors and strategies for improvement. Drugs Aging. 2008, 25: 1033-1047. 10.2165/0002512-200825120-00005.CrossRefPubMed
17.
go back to reference Jackson SH, Jansen PA, Mangoni AA: Off-label prescribing in older patients. Drugs Aging. 2012, 29: 427-434. 10.2165/11633520-000000000-00000.CrossRefPubMed Jackson SH, Jansen PA, Mangoni AA: Off-label prescribing in older patients. Drugs Aging. 2012, 29: 427-434. 10.2165/11633520-000000000-00000.CrossRefPubMed
18.
go back to reference Holland R, Lenaghan E, Harvey I, Smith R, Shepstone L, Lipp A, et al: Does home based medication review keep older people out of hospital? The HOMER randomised controlled trial. BMJ. 2005, 330: 293-10.1136/bmj.38338.674583.AE.CrossRefPubMedPubMedCentral Holland R, Lenaghan E, Harvey I, Smith R, Shepstone L, Lipp A, et al: Does home based medication review keep older people out of hospital? The HOMER randomised controlled trial. BMJ. 2005, 330: 293-10.1136/bmj.38338.674583.AE.CrossRefPubMedPubMedCentral
19.
go back to reference Holland R, Smith R, Harvey I: Where now for pharmacist led medication review?. J Epidemiol Community Health. 2006, 60: 92-93. 10.1136/jech.2005.035188.CrossRefPubMedPubMedCentral Holland R, Smith R, Harvey I: Where now for pharmacist led medication review?. J Epidemiol Community Health. 2006, 60: 92-93. 10.1136/jech.2005.035188.CrossRefPubMedPubMedCentral
20.
go back to reference Holland R, Desborough J, Goodyer L, Hall S, Wright D, Loke YK: Does pharmacist-led medication review help to reduce hospital admissions and deaths in older people? A systematic review and meta-analysis. Br J Clin Pharmacol. 2008, 65: 303-316. 10.1111/j.1365-2125.2007.03071.x.CrossRefPubMed Holland R, Desborough J, Goodyer L, Hall S, Wright D, Loke YK: Does pharmacist-led medication review help to reduce hospital admissions and deaths in older people? A systematic review and meta-analysis. Br J Clin Pharmacol. 2008, 65: 303-316. 10.1111/j.1365-2125.2007.03071.x.CrossRefPubMed
21.
go back to reference Schaefer M, Schulz M, Emmermann A, Mühlbauer K, Verheyen F: Manuale zur Pharmazeutischen Betreuung-Band 1: Grundlagen der Pharmazeutischen Betreuung [manual fo pharmaceutical care: part I: basics]. 2000, ABDA-Bundesvereinigung Deutscher Apotheker GOVI-Verlag Eschborn Schaefer M, Schulz M, Emmermann A, Mühlbauer K, Verheyen F: Manuale zur Pharmazeutischen Betreuung-Band 1: Grundlagen der Pharmazeutischen Betreuung [manual fo pharmaceutical care: part I: basics]. 2000, ABDA-Bundesvereinigung Deutscher Apotheker GOVI-Verlag Eschborn
22.
go back to reference Fiss T: Erfassung und Lösung arzneimittelbezogener Probleme in einer Kohorte älterer, multimorbider Hausbesuchspatienten. 2011, Hamburg: Verlag Dr. Kovac GmbH, Eschborn preceding to the year 2000 Fiss T: Erfassung und Lösung arzneimittelbezogener Probleme in einer Kohorte älterer, multimorbider Hausbesuchspatienten. 2011, Hamburg: Verlag Dr. Kovac GmbH, Eschborn preceding to the year 2000
23.
go back to reference Maidment ID, Fox C, Boustani M, Katona C: Medication management-the missing link in dementia interventions. Circulation. 2006, 114 (13): 1432-1445. 10.1161/CIRCULATIONAHA.106.177322.CrossRef Maidment ID, Fox C, Boustani M, Katona C: Medication management-the missing link in dementia interventions. Circulation. 2006, 114 (13): 1432-1445. 10.1161/CIRCULATIONAHA.106.177322.CrossRef
24.
go back to reference Krumholz HM, Currie PM, Riegel B, Phillips CO, Peterson ED, Smith R, et al: A taxonomy for disease management: a scientific statement from the American Heart Association Disease Management Taxonomy Writing Group. Circulation. 2006, 114: 1432-1445. 10.1161/CIRCULATIONAHA.106.177322.CrossRefPubMed Krumholz HM, Currie PM, Riegel B, Phillips CO, Peterson ED, Smith R, et al: A taxonomy for disease management: a scientific statement from the American Heart Association Disease Management Taxonomy Writing Group. Circulation. 2006, 114: 1432-1445. 10.1161/CIRCULATIONAHA.106.177322.CrossRefPubMed
25.
go back to reference Eickhoff C, Schulz M: Pharmaceutical care in community pharmacies: practice and research in Germany. Ann Pharmacother. 2006, 40: 729-735. 10.1345/aph.1G458.CrossRefPubMed Eickhoff C, Schulz M: Pharmaceutical care in community pharmacies: practice and research in Germany. Ann Pharmacother. 2006, 40: 729-735. 10.1345/aph.1G458.CrossRefPubMed
26.
go back to reference Karopka T, Bruder I, van den Berg N, Hoffmann W, Heuer A: ICT architecture for a community medicine nurse project. Healthinf 2008: Proc First Int Conf Health Inform. 2008, 2: 26-30. Karopka T, Bruder I, van den Berg N, Hoffmann W, Heuer A: ICT architecture for a community medicine nurse project. Healthinf 2008: Proc First Int Conf Health Inform. 2008, 2: 26-30.
27.
go back to reference Thyrian JR, Fiss T, Dreier A, Bowing G, Angelow A, Lueke S, et al: Life-and person-centred help in Mecklenburg-Western Pomerania, Germany (DelpHi): study protocol for a randomised controlled trial. Trials. 2012, 13: 56-10.1186/1745-6215-13-56.CrossRefPubMedPubMedCentral Thyrian JR, Fiss T, Dreier A, Bowing G, Angelow A, Lueke S, et al: Life-and person-centred help in Mecklenburg-Western Pomerania, Germany (DelpHi): study protocol for a randomised controlled trial. Trials. 2012, 13: 56-10.1186/1745-6215-13-56.CrossRefPubMedPubMedCentral
28.
go back to reference Kalbe E, Kessler J, Calabrese P, Smith R, Passmore AP, Brand M, et al: DemTect: a new, sensitive cognitive screening test to support the diagnosis of mild cognitive impairment and early dementia. Int J Geriatr Psychiatry. 2004, 19: 136-143. 10.1002/gps.1042.CrossRefPubMed Kalbe E, Kessler J, Calabrese P, Smith R, Passmore AP, Brand M, et al: DemTect: a new, sensitive cognitive screening test to support the diagnosis of mild cognitive impairment and early dementia. Int J Geriatr Psychiatry. 2004, 19: 136-143. 10.1002/gps.1042.CrossRefPubMed
29.
go back to reference Dreier A, Thyrian JR, Hoffmann W: Dementia care manager in der ambulanten Demenzversorgung: Entwicklung einer innovativen Qualifizierung für Pflegefachkräfte. Pflege&Gesellschaft. 2011, 16: 53-64. Dreier A, Thyrian JR, Hoffmann W: Dementia care manager in der ambulanten Demenzversorgung: Entwicklung einer innovativen Qualifizierung für Pflegefachkräfte. Pflege&Gesellschaft. 2011, 16: 53-64.
30.
go back to reference Sandholzer H, Hellenbrand W, Renteln-Kruse W, Van WC, Walker P: STEP–standardized assessment of elderly people in primary care. Dtsch Med Wochenschr. 2004, 129 (Suppl 4): S183-S226.CrossRefPubMed Sandholzer H, Hellenbrand W, Renteln-Kruse W, Van WC, Walker P: STEP–standardized assessment of elderly people in primary care. Dtsch Med Wochenschr. 2004, 129 (Suppl 4): S183-S226.CrossRefPubMed
31.
go back to reference Zaudig M: A new systematic method of measurement and diagnosis of “mild cognitive impairment” and dementia according to ICD-10 and DSM-III-R criteria. Int Psychogeriatr. 1992, 4 (Suppl 2): 203-219.CrossRefPubMed Zaudig M: A new systematic method of measurement and diagnosis of “mild cognitive impairment” and dementia according to ICD-10 and DSM-III-R criteria. Int Psychogeriatr. 1992, 4 (Suppl 2): 203-219.CrossRefPubMed
32.
go back to reference Fiss T, Ritter CA, Alte D, van den Berg N, Hoffmann W: Detection of drug related problems in an interdisciplinary health care model for rural areas in Germany. Pharm World Sci. 2010, 32: 566-576. 10.1007/s11096-010-9409-6.CrossRefPubMed Fiss T, Ritter CA, Alte D, van den Berg N, Hoffmann W: Detection of drug related problems in an interdisciplinary health care model for rural areas in Germany. Pharm World Sci. 2010, 32: 566-576. 10.1007/s11096-010-9409-6.CrossRefPubMed
33.
go back to reference de KE, Van der HD, Landewe R, Van der TH, Van der LS: The compliance-questionnaire-rheumatology compared with electronic medication event monitoring: a validation study. J Rheumatol. 2003, 30: 2469-2475. de KE, Van der HD, Landewe R, Van der TH, Van der LS: The compliance-questionnaire-rheumatology compared with electronic medication event monitoring: a validation study. J Rheumatol. 2003, 30: 2469-2475.
34.
go back to reference Morisky DE, Green LW, Levine DM: Concurrent and predictive validity of a self-reported measure of medication adherence. Med Care. 1986, 24: 67-74. 10.1097/00005650-198601000-00007.CrossRefPubMed Morisky DE, Green LW, Levine DM: Concurrent and predictive validity of a self-reported measure of medication adherence. Med Care. 1986, 24: 67-74. 10.1097/00005650-198601000-00007.CrossRefPubMed
35.
go back to reference Thompson K, Kulkarni J, Sergejew AA: Reliability and validity of a new Medication Adherence Rating Scale (MARS) for the psychoses. Schizophr Res. 2000, 42: 241-247. 10.1016/S0920-9964(99)00130-9.CrossRefPubMed Thompson K, Kulkarni J, Sergejew AA: Reliability and validity of a new Medication Adherence Rating Scale (MARS) for the psychoses. Schizophr Res. 2000, 42: 241-247. 10.1016/S0920-9964(99)00130-9.CrossRefPubMed
36.
go back to reference Jank S, Bertsche T, Schellberg D, Herzog W, Haefeli WE: The A14-scale: development and evaluation of a questionnaire for assessment of adherence and individual barriers. Pharm World Sci. 2009, 31 (4): 426-431. 10.1007/s11096-009-9296-x.CrossRefPubMed Jank S, Bertsche T, Schellberg D, Herzog W, Haefeli WE: The A14-scale: development and evaluation of a questionnaire for assessment of adherence and individual barriers. Pharm World Sci. 2009, 31 (4): 426-431. 10.1007/s11096-009-9296-x.CrossRefPubMed
37.
go back to reference Meyer J, Ostrzinski S, Fredrich D, Havemann C, Krafczyk J, Hoffmann W: Efficient data management in a large-scale epidemiology research project. Comput Methods Programs Biomed. 2012, 107: 425-435. 10.1016/j.cmpb.2010.12.016.CrossRefPubMed Meyer J, Ostrzinski S, Fredrich D, Havemann C, Krafczyk J, Hoffmann W: Efficient data management in a large-scale epidemiology research project. Comput Methods Programs Biomed. 2012, 107: 425-435. 10.1016/j.cmpb.2010.12.016.CrossRefPubMed
38.
go back to reference Hansten PD, Horn JR, Hazlet TK: ORCA: OpeRational classificAtion of drug interactions. J Am Pharm Assoc (Wash ). 2001, 41: 161-165.CrossRef Hansten PD, Horn JR, Hazlet TK: ORCA: OpeRational classificAtion of drug interactions. J Am Pharm Assoc (Wash ). 2001, 41: 161-165.CrossRef
39.
go back to reference Vonbach P, Dubied A, Krahenbuhl S, Beer JH: Evaluation of frequently used drug interaction screening programs. Pharm World Sci. 2008, 30: 367-374. 10.1007/s11096-008-9191-x.CrossRefPubMed Vonbach P, Dubied A, Krahenbuhl S, Beer JH: Evaluation of frequently used drug interaction screening programs. Pharm World Sci. 2008, 30: 367-374. 10.1007/s11096-008-9191-x.CrossRefPubMed
41.
go back to reference Beers MH, Ouslander JG, Rollingher I, Reuben DB, Brooks J, Beck JC: Explicit criteria for determining inappropriate medication use in nursing home residents. UCLA Division of Geriatric Medicine. Arch Intern Med. 1991, 151: 1825-1832. 10.1001/archinte.1991.00400090107019.CrossRefPubMed Beers MH, Ouslander JG, Rollingher I, Reuben DB, Brooks J, Beck JC: Explicit criteria for determining inappropriate medication use in nursing home residents. UCLA Division of Geriatric Medicine. Arch Intern Med. 1991, 151: 1825-1832. 10.1001/archinte.1991.00400090107019.CrossRefPubMed
42.
go back to reference Chien WT, Lee IY: Randomized controlled trial of a dementia care programme for families of home-resided older people with dementia. J Adv Nurs. 2010, 67 (4): 774-87.CrossRefPubMed Chien WT, Lee IY: Randomized controlled trial of a dementia care programme for families of home-resided older people with dementia. J Adv Nurs. 2010, 67 (4): 774-87.CrossRefPubMed
43.
go back to reference Zuckerman IH, Hernandez JJ, Gruber-Baldini AL, Hebel JR, Stuart B, Zimmerman S, Magaziner J: Potentially inappropriate prescribing before and after nursing home admission among patients with and without dementia. Am J Geriatr Pharmacother. 2005, 3: 246-254. 10.1016/j.amjopharm.2005.12.007.CrossRefPubMed Zuckerman IH, Hernandez JJ, Gruber-Baldini AL, Hebel JR, Stuart B, Zimmerman S, Magaziner J: Potentially inappropriate prescribing before and after nursing home admission among patients with and without dementia. Am J Geriatr Pharmacother. 2005, 3: 246-254. 10.1016/j.amjopharm.2005.12.007.CrossRefPubMed
44.
go back to reference Geurts MM, Talsma J, Brouwers JR, De Gier JJ: Medication review and reconciliation with cooperation between pharmacist and general practitioner and the benefit for the patient: a systematic review. Br J Clin Pharmacol. 2012 Geurts MM, Talsma J, Brouwers JR, De Gier JJ: Medication review and reconciliation with cooperation between pharmacist and general practitioner and the benefit for the patient: a systematic review. Br J Clin Pharmacol. 2012
45.
go back to reference Topinkova E, Baeyens JP, Michel JP, Lang PO: Evidence-based strategies for the optimization of pharmacotherapy in older people. Drugs Aging. 2012, 29: 477-494. 10.2165/11632400-000000000-00000.CrossRefPubMed Topinkova E, Baeyens JP, Michel JP, Lang PO: Evidence-based strategies for the optimization of pharmacotherapy in older people. Drugs Aging. 2012, 29: 477-494. 10.2165/11632400-000000000-00000.CrossRefPubMed
46.
go back to reference Schaefer M: Systematic drug documentation. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2005, 48: 736-741. 10.1007/s00103-005-1072-z.CrossRefPubMed Schaefer M: Systematic drug documentation. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2005, 48: 736-741. 10.1007/s00103-005-1072-z.CrossRefPubMed
47.
go back to reference Spinewine A, Fialova D, Byrne S: The role of the pharmacist in optimizing pharmacotherapy in older people. Drugs Aging. 2012, 29: 495-510. 10.2165/11631720-000000000-00000.CrossRefPubMed Spinewine A, Fialova D, Byrne S: The role of the pharmacist in optimizing pharmacotherapy in older people. Drugs Aging. 2012, 29: 495-510. 10.2165/11631720-000000000-00000.CrossRefPubMed
Metadata
Title
Medication management for people with dementia in primary care: description of implementation in the DelpHi study
Authors
Thomas Fiß
Jochen René Thyrian
Diana Wucherer
Grit Aßmann
Ingo Kilimann
Stefan J Teipel
Wolfgang Hoffmann
Publication date
01-12-2013
Publisher
BioMed Central
Published in
BMC Geriatrics / Issue 1/2013
Electronic ISSN: 1471-2318
DOI
https://doi.org/10.1186/1471-2318-13-121

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