Published in:
Open Access
01-12-2022 | Malignant Hyperthermia | Case report
Use of remimazolam in living donor liver transplantation: a case report
Authors:
Tsuguhiro Matsumoto, Kotaro Sakurai, Kazuyo Takahashi, Shuji Kawamoto
Published in:
JA Clinical Reports
|
Issue 1/2022
Login to get access
Abstract
Background
Remimazolam is an intravenous ultra-short-acting benzodiazepine with the benefit of hemodynamic stability, including blood pressure and pulse rate. We report a case in which remimazolam was used in living donor liver transplantation with stable hemodynamics.
Case presentation
A 19-year-old woman underwent living donor liver transplantation due to end-stage liver disease, which is associated with a hyperdynamic state and hemodynamic instability. The patient’s sister had a history of malignant hyperthermia, so we chose total intravenous anesthesia with remimazolam. Intraoperative bleeding of seven liters occurred, but she had mild intraoperative blood pressure changes, and continuous catecholamine administration was not necessary. The patient had no memories or discomfort during the surgery.
Conclusions
We maintained stable hemodynamics using remimazolam for anesthetic management of a patient undergoing a liver transplantation, which is characterized by a hyperdynamic state and circulatory instability.