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JA Clinical Reports

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Open Access 01-12-2022 | Case report

Rapid cyclic fluctuations in blood pressure during two surgeries associated with pheochromocytoma: a case report

Authors: Tomoyuki Watanabe, Hirotsugu Miyoshi, Ryuji Nakamura, Sachiko Otsuki, Noboru Saeki, Yasuo M. Tsutsumi

Published in: JA Clinical Reports | Issue 1/2022

Abstract

Background

We measured catecholamine levels during periodic blood pressure fluctuations in patients with pheochromocytoma.

Case presentation

A 43-year-old man presented with periodic blood pressure fluctuations during surgery for a renal pelvic tumor. His blood levels of catecholamines (ng/mL) changed dramatically over a short time during blood pressure fluctuations: adrenaline 0.36 to 3.22, noradrenaline 0.47 to 1.98, and dopamine 0.02. After the diagnosis of pheochromocytoma, oral treatment with doxazosin 2 mg/day was administered, and left adrenalectomy was performed 4 months after the initial surgery. Periodic circulation fluctuations occurred after tracheal intubation at the time of anesthesia induction, but the degree of fluctuation was smaller than that of the first surgery.

Conclusions

The data suggest that the periodic blood pressure fluctuations in pheochromocytoma patients are caused by changes in blood catecholamine levels. Our data suggests that alpha blockers may also be effective against the cyclic fluctuations that occur in patients with pheochromocytoma.

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Title: Rapid cyclic fluctuations in blood pressure during two surgeries associated with pheochromocytoma: a case report
Authors: Tomoyuki Watanabe
Hirotsugu Miyoshi
Ryuji Nakamura
Sachiko Otsuki
Noboru Saeki
Yasuo M. Tsutsumi
Publication date: 01-12-2022
Publisher: Springer Berlin Heidelberg
Published in: JA Clinical Reports / Issue 1/2022
Electronic ISSN: 2363-9024
DOI: https://doi.org/10.1186/s40981-022-00569-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Rapid cyclic fluctuations in blood pressure during two surgeries associated with pheochromocytoma: a case report

Abstract

Background

Case presentation

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Case presentation

Conclusions

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