Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
Malaria Journal
Published in: Malaria Journal 1/2020

Open Access 01-12-2020 | Malaria | Commentary

Highlighting the burden of malarial infection and disease in the neonatal period: making sense of different concepts

Authors: Abel Nhama, Rosauro Varo, Quique Bassat

Published in: Malaria Journal | Issue 1/2020

Login to get access

Excerpt

In malaria-endemic areas, the first year of life is indisputably considered one of the most vulnerable periods for malaria disease, and malaria-associated mortality in this age group is typically high, usually as a consequence of severe anaemia, among other possible complications [1]. However, malaria disease during the first 4 weeks of life (which includes both congenital and neonatal malaria) is comparatively much less common than among older infants. Congenital and neonatal malaria show important differences in terms of acquisition route and timing of the infection. They both are also importantly influenced by background malaria endemicity and degrees of population-acquired immunity. …
Literature
1.
WHO. World malaria report 2019. Geneva, World Health Organization, 2019.
2.
Menendez C, Mayor A. Congenital malaria: the least known consequence of malaria in pregnancy. Semin Fetal Neonatal Med. 2007;12:207–13.CrossRef
3.
Doolan DL, Dobaño C, Baird JK. Acquired immunity to malaria. Clin Microbiol Rev. 2009;22:13–36.CrossRef
4.
Galatas B, Bassat Q, Mayor A. Malaria parasites in the asymptomatic: looking for the hay in the haystack. Trends Parasitol. 2016;32:296–308.CrossRef
5.
Guinovart C, Bassat Q, Sigaúque B, Aide P, Sacarlal J, Nhampossa T, et al. Malaria in rural Mozambique. Part I children attending the outpatient clinic. Malar J. 2008;7:36.CrossRef
6.
Amaratunga C, Lopera-Mesa TM, Brittain NJ, Cholera R, Arie T, Fujioka H, et al. A role for fetal hemoglobin and maternal immune IgG in infant resistance to Plasmodium falciparum malaria. PLoS ONE. 2011;6:e14798.CrossRef
7.
Tobian AA, Mehlotra RK, Malhotra I, Wamachi A, Mungai P, Koech D, et al. Frequent umbilical cord-blood and maternal-blood infections with Plasmodium falciparum, P malariae, and P. ovale in Kenya. J Infect Dis. 2000;182:558–63.CrossRef
8.
McGovern LM, Boyce TG, Fischer PR. Congenital infections associated with international travel during pregnancy. J Travel Med. 2007;14:117–28.CrossRef
9.
Rai P, Majumdar K, Sharma S, Chauhan R, Chandra J. Congenital malaria in a neonate: case report with a comprehensive review on differential diagnosis, treatment and prevention in Indian perspective. J Parasit Dis. 2015;39:345–8.CrossRef
10.
Tao ZY, Fang Q, Liu X, Culleton R, Tao L, Xia H, et al. Congenital malaria in China. PLoS Negl Trop Dis. 2014;8:e2622.CrossRef
11.
Vottier G, Arsac M, Farnoux C, Mariani-Kurkdjian P, Baud O, Aujard Y. Congenital malaria in neonates: two case reports and review of the literature. Acta Paediatr. 2008;97:505–8.CrossRef
12.
Lesko CR, Arguin PM, Newman RD. Congenital malaria in the United States: a review of cases from 1966 to 2005. Arch Pediatr Adolesc Med. 2007;161:1062–7.CrossRef
13.
Pengsaa K. Congenital malaria in Thailand. Ann Trop Paediatr. 2007;27:133–9.CrossRef
14.
Danwang C, Bigma JJ, Tuku Nzalie RN, Robert A. Epidemiology of clinical congenital and neonatal malaria in endemic settings: a systematic review and meta-analysis. Mala J. 2020;19:in press.
15.
Bilal JA, Malik EE, Al-Nafeesah A, Adam I. Global prevalence of congenital malaria: A systematic review and meta-analysis. Eur J Obstet Gynecol Reprod Biol. 2020;S0301-2115(20)30392-4. Online ahead of print.
16.
D’Alessandro U, Ubben D, Hamed K, Ceesay SJ, Okebe J, Taal M, et al. Malaria in infants aged less than six months –is it an area of unmet medical need? Malar J. 2012;11:400.CrossRef
Metadata
Title
Highlighting the burden of malarial infection and disease in the neonatal period: making sense of different concepts
Authors
Abel Nhama
Rosauro Varo
Quique Bassat
Publication date
01-12-2020
Publisher
BioMed Central
Keyword
Malaria
Published in
Malaria Journal / Issue 1/2020
Electronic ISSN: 1475-2875
DOI
https://doi.org/10.1186/s12936-020-03394-3

Other articles of this Issue 1/2020

Malaria Journal 1/2020 Go to the issue

Research

Cost-effectiveness of rapid diagnostic tests, compared to microscopic tests, for the diagnosis and treatment of gestational malaria in Colombia from an institutional perspective

Research

Community factors affecting participation in larval source management for malaria control in Chikwawa District, Southern Malawi

Research

Amplicon deep sequencing of kelch13 in Plasmodium falciparum isolates from Senegal

Research

Genetic diversity of Plasmodium falciparum and genetic profile in children affected by uncomplicated malaria in Cameroon

Case study

Classification of induced malaria case in an elimination setting: investigation of transfusion-transmitted malaria cases

Research

Genetic polymorphism of merozoite surface protein-3 in Myanmar Plasmodium falciparum field isolates
Obesity Clinical Trial Summary

At a glance: The STEP trials

Read more

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Pediatric Cardiology Video

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

Cardiopulmonary Comorbidity Video

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Valvular Heart Disease Video

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discuss last year's major advances in heart failure and cardiomyopathies.

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discuss last year's major advances in heart failure and cardiomyopathies.

Watch now

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

Incentivised to exercise

11-04-2024 Lifestyle Modifications News

New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

Image Credits