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Published in: Insights into Imaging 1/2023

Open Access 01-12-2023 | Magnetic Resonance Imaging | Educational Review

Radiologic-pathologic correlation of prostatic cancer extracapsular extension (ECE)

Authors: Adalgisa Guerra, Beatriz Flor-de-Lima, Gonçalo Freire, Ana Lopes, João Cassis

Published in: Insights into Imaging | Issue 1/2023

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Abstract

Recent advancements on nerve-sparing robotic prostatectomy allow fewer side effects such as urinary incontinence and sexual dysfunction. To perform such techniques, it is essential for the surgeon to know if the neurovascular bundle is involved. Despite being the gold-standard imaging method for Prostate Cancer (PCa) staging, Magnetic Resonance Imaging (MRI) lacks high specificity for detecting extracapsular extension (ECE). Therefore, it is essential to understand the pathologic aspects of ECE to better evaluate the MRI findings of PCa. We reviewed the normal MRI appearance of the prostate gland and the periprostatic space and correlated them to prostatectomy specimens. The different findings of ECE and neurovascular bundle invasion are exemplified with images of both MRI and histologic specimens.

Graphical abstract

Literature
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go back to reference Magi-Galluzzi C, Evans AJ, Delahunt B, et al (2011) International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 3: extraprostatic extension, lymphovascular invasion and locally advanced disease. Mod Pathol 24:26–38. https://doi.org/10.1038/MODPATHOL.2010.158 Magi-Galluzzi C, Evans AJ, Delahunt B, et al (2011) International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 3: extraprostatic extension, lymphovascular invasion and locally advanced disease. Mod Pathol 24:26–38. https://​doi.​org/​10.​1038/​MODPATHOL.​2010.​158
Metadata
Title
Radiologic-pathologic correlation of prostatic cancer extracapsular extension (ECE)
Authors
Adalgisa Guerra
Beatriz Flor-de-Lima
Gonçalo Freire
Ana Lopes
João Cassis
Publication date
01-12-2023
Publisher
Springer Vienna
Published in
Insights into Imaging / Issue 1/2023
Electronic ISSN: 1869-4101
DOI
https://doi.org/10.1186/s13244-023-01428-3

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