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01-09-2019 | Lymphoma | Case Report

Post-transplant lymphoproliferative disorder manifesting as lymphomatoid granulomatosis: report of two cases and review of the literature highlighting current challenges in pathologic classification

Authors: Jonathan J. Douds, Joyce E. Johnson, Ty W. Abel, John P. Greer, Mary Ann Thompson, Alexandra E. Kovach

Published in: Journal of Hematopathology | Issue 3/2019

Abstract

Classification of viral- and immunodeficiency-associated lymphoproliferative disorders continues to evolve. Entities in these categories recognized in the 2016 revision of the World Health Organization Classification of Lymphoid Neoplasms show considerable morphologic overlap, and it is unclear whether the current classification conceptualizes the scenarios in which these lesions arise and how they might be best managed. Here, we report two cases of lymphoproliferative disorders meeting histologic criteria for lymphomatoid granulomatosis that arose following solid organ transplant. In reviewing the clinicopathologic features of these examples and those of similar cases in the literature, we highlight challenges in current classification and opportunities for their refinement.

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Title: Post-transplant lymphoproliferative disorder manifesting as lymphomatoid granulomatosis: report of two cases and review of the literature highlighting current challenges in pathologic classification
Authors: Jonathan J. Douds
Joyce E. Johnson
Ty W. Abel
John P. Greer
Mary Ann Thompson
Alexandra E. Kovach
Publication date: 01-09-2019
Publisher: Springer Berlin Heidelberg
Keywords: Lymphoma
Epstein-Barr Virus
Rituximab
Immunodeficiency
Rituximab
Published in: Journal of Hematopathology / Issue 3/2019
Print ISSN: 1868-9256
Electronic ISSN: 1865-5785
DOI: https://doi.org/10.1007/s12308-019-00364-w

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Post-transplant lymphoproliferative disorder manifesting as lymphomatoid granulomatosis: report of two cases and review of the literature highlighting current challenges in pathologic classification

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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