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01-04-2015 | Original Article

Long-term results of thulium laser resection of the prostate: a prospective study at multiple centers

Authors: Feng Sun, Bangmin Han, Di Cui, Fujun Zhao, Xiaowen Sun, Jian Zhuo, Yifeng Jing, Haitao Liu, Shujie Xia, Yong Yang, Guangheng Luo, Fengfu Guo

Published in: World Journal of Urology | Issue 4/2015

Abstract

Purpose

To evaluate the long-term durability and complication rates after thulium laser resection of prostate (TmLRP) through a prospective multiple-center study.

Materials and methods

From November 2004 to December 2011, we prospectively studied 2,216 patients with symptomatic benign prostatic hyperplasia (BPH) treated with thulium laser resection of the prostate at four medical centers. Patients were assessed on International Prostate Symptom Score (IPSS), quality of life (QoL), maximum urinary flow rate (Q_max), and postvoid residual urine (PVR). Perioperative complications were classified according to the modified Clavien classification system.

Results

Of 2,216 patients treated with TmLRP, 1,353 (61.1 %), 1,129 (50.9 %), 847 (38.2 %), and 541 (24.4 %) patients were followed at 5, 6, 7, and 8 years, respectively. Postoperatively, IPSS, QoL, Q_max, and PVR showed a significant improvement from 3 month after surgery and remained significantly improved during the entire follow-up period (p < 0.01). Minor complications occurred in 526 (23.7 %) of the 2,216 patients (Clavien 1: 21.5 %; Clavien 2: 2.3 %). Major complications requiring re-interventions occurred in 48 (2.2 %) of the 2,216 patients (Clavien 3: 2.2 %). No Clavien 4 or Clavien 5 complication had occurred. Urethral stricture and bladder neck contracture occurred in 2.6 % (58) and 1.6 % (35) patients, respectively. Persistent stress incontinence was found in 0.1 % (2) of the patients. Re-operation as a result of BPH recurrence was required in 1.2 % (27) patients.

Conclusions

Thulium laser resection of the prostate is a safe and effective procedure with excellent durability in the treatment of symptomatic BPH.

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Title: Long-term results of thulium laser resection of the prostate: a prospective study at multiple centers
Authors: Feng Sun
Bangmin Han
Di Cui
Fujun Zhao
Xiaowen Sun
Jian Zhuo
Yifeng Jing
Haitao Liu
Shujie Xia
Yong Yang
Guangheng Luo
Fengfu Guo
Publication date: 01-04-2015
Publisher: Springer Berlin Heidelberg
Published in: World Journal of Urology / Issue 4/2015
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI: https://doi.org/10.1007/s00345-014-1456-5

At a glance: The STEP trials

Springer Medicine

Long-term results of thulium laser resection of the prostate: a prospective study at multiple centers

Abstract

Purpose

Materials and methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose

Materials and methods

Results

Conclusions

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