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World Journal of Urology
Published in: World Journal of Urology 4/2015

01-04-2015 | Topic Paper

Transurethral anatomical enucleation of the prostate with Tm:YAG support (ThuLEP): review of the literature on a novel surgical approach in the management of benign prostatic enlargement

Authors: Iason Kyriazis, Piotr P. Świniarski, Stephan Jutzi, Mathias Wolters, Christopher Netsch, Martin Burchardt, Evangelos Liatsikos, Shujie Xia, Thorsten Bach, Andreas J. Gross, Thomas R. W. Herrmann

Published in: World Journal of Urology | Issue 4/2015

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Abstract

Purpose

Retrograde transurethral anatomical enucleation of the prostate is gaining momentum as a new concept in transurethral surgery of benign prostatic hyperplasia. Its adaptation is boosted by the familiarity of urologists with the finger-assisted anatomical enucleation of the adenoma during open prostatectomy and the combination of this well-established concept with the minimal invasive characteristics of transurethral surgery. The thulium laser appears as an ideal energy source for such operation. In this work, current evidence on thulium laser-assisted anatomical enucleation of the prostate (ThuLEP) is being reviewed.

Materials and Methods

A comprehensive literature review was performed on Medline, PubMed, and Cochrane databases retrieving all literature on thulium laser-assisted prostatectomy between 2006 and 2015. Experimental studies, review articles and editorial comments as well as studies on thulium laser-assisted approaches other than ThuLEP (i.e., ThuVEP, ThuVAP or ThuVARP) were excluded from the analysis.

Results

In total, six original articles on either surgical technique or clinical outcomes were retrieved. With regard to functional results, ThuLEP presented no significant differences toward the standard treatment (TURP/HoLEP) arm in two randomized controlled trials and favorable outcomes in available prospective cohorts. Observed morbidity was minimum and comparable with the rest of transurethral literature.

Conclusions

ThuLEP literature is still very limited. Based on the available data, the approach is safe and effective, demonstrating favorable outcomes, comparable with the current standard treatment options. Further documentation of ThuLEP outcomes is necessary to define the optimum indications of this novel technique.
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Metadata
Title
Transurethral anatomical enucleation of the prostate with Tm:YAG support (ThuLEP): review of the literature on a novel surgical approach in the management of benign prostatic enlargement
Authors
Iason Kyriazis
Piotr P. Świniarski
Stephan Jutzi
Mathias Wolters
Christopher Netsch
Martin Burchardt
Evangelos Liatsikos
Shujie Xia
Thorsten Bach
Andreas J. Gross
Thomas R. W. Herrmann
Publication date
01-04-2015
Publisher
Springer Berlin Heidelberg
Published in
World Journal of Urology / Issue 4/2015
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI
https://doi.org/10.1007/s00345-015-1529-0

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