Skip to main content
Top
Published in: Annals of Surgical Oncology 13/2022

13-09-2022 | Hepatocellular Carcinoma | ASO Author Reflections

ASO Author Reflections: Understanding How to Improve Surveillance in Hepatocellular Carcinoma

Authors: Marianna V. Papageorge, MD, MPH, Teviah E. Sachs, MD, MPH

Published in: Annals of Surgical Oncology | Issue 13/2022

Login to get access

Excerpt

Routine screening for hepatocellular carcinoma (HCC) is currently recommended among high-risk patients, including those with cirrhosis, hepatitis B, and hepatitis C. Prior studies have demonstrated that although adherence to screening guidelines is associated with earlier stage of diagnosis, receipt of curative treatment and improved survival, fewer than 25% of eligible patients undergo appropriate surveillance.1,2 This is thought to be in large part due to insurance status and access to healthcare resources, particularly as patients with risk factors for HCC are often of a more vulnerable cohort.3 More so, as the median age of diagnosis is 62 years in the US, it can be hypothesized that these low screening rates are more pronounced among older patients. This study evaluated surveillance patterns and the association with stage at diagnosis and overall survival in the older, insured population represented by SEER-Medicare.4
Literature
1.
go back to reference Singal AG, Zhang E, Narasimman M, Rich NE, Waljee AK, YujinHoshida J, et al. HCC surveillance improves early detection, curative treatment receipt, and survival in patients with cirrhosis: a systematic review and meta-analysis. J Hepatol. 2022;77(1):128–39.CrossRefPubMed Singal AG, Zhang E, Narasimman M, Rich NE, Waljee AK, YujinHoshida J, et al. HCC surveillance improves early detection, curative treatment receipt, and survival in patients with cirrhosis: a systematic review and meta-analysis. J Hepatol. 2022;77(1):128–39.CrossRefPubMed
2.
go back to reference Tran SA, Le AN, Zhao C, Hoang J, Yasukawa LA, Weber S, et al. Rate of hepatocellular carcinoma surveillance remains low for a large, real-life cohort of patients with hepatitis C cirrhosis. BMJ Open Gastroenterol. 2018;5(1):e000192.CrossRefPubMedPubMedCentral Tran SA, Le AN, Zhao C, Hoang J, Yasukawa LA, Weber S, et al. Rate of hepatocellular carcinoma surveillance remains low for a large, real-life cohort of patients with hepatitis C cirrhosis. BMJ Open Gastroenterol. 2018;5(1):e000192.CrossRefPubMedPubMedCentral
3.
go back to reference Kronenfeld JP, Goel N. An analysis of individual and contextual-level disparities in screening, treatment, and outcomes for hepatocellular carcinoma. J Hepatocell Carcinoma. 2021;8:1209–19.CrossRefPubMedPubMedCentral Kronenfeld JP, Goel N. An analysis of individual and contextual-level disparities in screening, treatment, and outcomes for hepatocellular carcinoma. J Hepatocell Carcinoma. 2021;8:1209–19.CrossRefPubMedPubMedCentral
5.
go back to reference Davila JA, Morgan RO, Richardson PA, Du XL, McGlynn KA, El-Serag HB. Use of surveillance for hepatocellular carcinoma among patients with cirrhosis in the United States. Hepatology. 2010;52(1):132–41.CrossRefPubMed Davila JA, Morgan RO, Richardson PA, Du XL, McGlynn KA, El-Serag HB. Use of surveillance for hepatocellular carcinoma among patients with cirrhosis in the United States. Hepatology. 2010;52(1):132–41.CrossRefPubMed
Metadata
Title
ASO Author Reflections: Understanding How to Improve Surveillance in Hepatocellular Carcinoma
Authors
Marianna V. Papageorge, MD, MPH
Teviah E. Sachs, MD, MPH
Publication date
13-09-2022
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology / Issue 13/2022
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-022-12523-y

Other articles of this Issue 13/2022

Annals of Surgical Oncology 13/2022 Go to the issue