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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 12/2021

01-11-2021 | Cholangiocarcinoma | ASO Author Reflections

The Role of Surgery in the Treatment of Bismuth–Corlette Type IV Perihilar Cholangiocarcinoma

Authors: Laura Alaimo, MD, Fabio Bagante, MD, PhD, Andrea Ruzzenente, MD, PhD

Published in: Annals of Surgical Oncology | Issue 12/2021

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Excerpt

Bismuth–Corlette (BC) type IV perihilar cholangiocarcinoma (pCCA) involving the second-order biliary ducts has traditionally been considered a locally advanced and unresectable tumor. In recent decades, several authors have proposed an aggressive surgical approach for the treatment of BC type IV pCCA, including extended hepatectomies (i.e., trisectionectomy) and vascular resections.1,2 Although these approaches might be associated with a higher risk of complications and in-hospital mortality, Eastern and Western authors recently reported that surgical resections with curative intent might represent a valid treatment option for these patients.1,3,4 …
Literature
1.
Ku D, Tang R, Pang T, Pleass H, Richardson A, Yuen L, et al. Survival outcomes of hepatic resections in Bismuth–Corlette type IV cholangiocarcinoma. ANZ J Surg. 2020;90(9):1604–14.CrossRef
2.
Mizuno T, Ebata T, Nagino M. Advanced hilar cholangiocarcinoma: an aggressive surgical approach for the treatment of advanced hilar cholangiocarcinoma—perioperative management, extended procedures, and multidisciplinary approaches. Surg Oncol. 2020;33:201–6.CrossRef
3.
Ebata T, Mizuno T, Yokoyama Y, Igami T, Sugawara G, Nagino M. Surgical resection for Bismuth type IV perihilar cholangiocarcinoma. Br J Surg. 2018;105(7):829–38.CrossRef
4.
Wiggers JK, Groot Koerkamp B, Cieslak KP, Doussot A, van Klaveren D, Allen PJ, et al. Postoperative mortality after liver resection for perihilar cholangiocarcinoma: development of a risk score and importance of biliary drainage of the future liver remnant. J Am Coll Surg. 2016;223(2):321–31e1.CrossRef
5.
Metadata
Title
The Role of Surgery in the Treatment of Bismuth–Corlette Type IV Perihilar Cholangiocarcinoma
Authors
Laura Alaimo, MD
Fabio Bagante, MD, PhD
Andrea Ruzzenente, MD, PhD
Publication date
01-11-2021
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology / Issue 12/2021
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-021-09980-2

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