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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 12/2021

01-11-2021 | Esophagus Resection | ASO Author Reflections

ASO Author Reflections: Serum Squamous Cell Carcinoma Antigen in Recurrent Esophageal Squamous Cell Carcinoma

Authors: Yasukazu Kanie, MD, Akihiko Okamura, MD, PhD, Masayuki Watanabe, MD, PhD, FACS

Published in: Annals of Surgical Oncology | Issue 12/2021

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Excerpt

Serum squamous cell carcinoma antigen (SCC-Ag) has been primarily identified in patients with uterine cervical squamous cell carcinoma. Increased serum SCC-Ag levels are often observed in patients with SCC, regardless of cancer origin. When managing patients with esophageal squamous cell carcinoma (ESCC), serum SCC-Ag is utilized for various purposes, such as preoperative assessment, therapeutic effect evaluation, or follow-up. …
Literature
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Suzuki T, Okamura A, Watanabe M, et al. Neoadjuvant Chemoradiotherapy with cisplatin plus fluorouracil for borderline resectable esophageal squamous cell carcinoma. Ann Surg Oncol. 2020;27:1510–7.CrossRef
2.
Okamura A, Matsuda S, Mayanagi S, et al. Clinical significance of pretherapeutic serum squamous cell carcinoma antigen level in patients with neoadjuvant chemotherapy for esophageal squamous cell carcinoma. Ann Surg Oncol. 2021;28:1209–16.CrossRef
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Kanda M, Koike M, Shimizu D, et al. Optimized cutoff value of serum squamous cell carcinoma antigen concentration accurately predicts recurrence after curative resection of squamous cell carcinoma of the esophagus. Ann Surg Oncol. 2020;27:1233–40.CrossRef
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Kato K, Cho BC, Takahashi M, et al. Nivolumab versus chemotherapy in patients with advanced oesophageal squamous cell carcinoma refractory or intolerant to previous chemotherapy (ATTRACTION-3): a multicentre, randomised, open-label, phase 3 trial. Lancet Oncol. 2019;20(11):1506–17.CrossRef
Metadata
Title
ASO Author Reflections: Serum Squamous Cell Carcinoma Antigen in Recurrent Esophageal Squamous Cell Carcinoma
Authors
Yasukazu Kanie, MD
Akihiko Okamura, MD, PhD
Masayuki Watanabe, MD, PhD, FACS
Publication date
01-11-2021
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology / Issue 12/2021
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-021-09986-w

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