Published in:
01-12-2020 | ASO Author Reflections
ASO Author Reflections: Margin-Positive Pancreatic Ductal Adenocarcinoma During Pancreaticoduodenectomy: Additional Resection Does Not Improve Survival
Authors:
Richard Zheng, MD, David Nauheim, BA, Jonathan Bassig, BS, Matthew Chadwick, BS, Christopher W. Schultz, PhD, Geoffrey Krampitz, MD, PhD, Harish Lavu, MD, FACS, Jordan R. Winter, MD, FACS, Charles J. Yeo, MD, FACS, Adam C. Berger, MD, FACS
Published in:
Annals of Surgical Oncology
|
Special Issue 3/2020
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Excerpt
Obtaining “frozen” resection margins during pancreaticoduodenectomy (PD) is a common practice, but the benefit of re-resecting positive margins has been debated. Recently, several large studies have suggested that resection of positive neck margins does not improve survival after PD.
1,
2 However, there is other evidence that contradicts these findings.
3,
4 For this reason, we sought to add more conclusive evidence to this discussion and performed a retrospective cohort study to assess the impact of resecting all commonly obtained margins—pancreatic neck, uncinate, and bile duct—separately and together.
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