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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 3/2020

01-12-2020 | Lung Cancer | Thoracic Oncology

Lung Cancer Associated with Cystic Airspaces in the Screening Perspective

Author: Mario Mascalchi, MD, PhD

Published in: Annals of Surgical Oncology | Special Issue 3/2020

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Excerpt

After demonstrating, in large trials, that low-dose computed tomography (LDCT) screening decreases lung cancer (LC) mortality1,2 in smokers and former smokers, establishing screening programs in high-risk subjects has become a priority for health systems. LC associated with cystic airspaces (LCCA) is a distinct although uncommon presentation of screen-detected LC, accounting for 2% of LCs identified at baseline and for 12% of LCs identified at annual repeat LDCT.3 …
Literature
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National Lung Screening Trial Research Team; Aberle DR, Adams AM, Berg CD, et al. Reduced lung-cancer mortality with low-dose computed tomographic screening. N Engl J Med. 2011;365:395–409.
2.
de Koning HJ, van der Aalst CM, de Jong PA et al. Reduced lung-cancer mortality with volume CT screening in a randomized trial. N Engl J Med. 2020;382:503–13.CrossRef
3.
Farooqi AO, Matt C, Lijuan Z, et al. Lung cancer associated with cystic airspaces. AJR Am J Roentgenol. 2012;199:781–6.CrossRef
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Sheard S, Moser J, Sayer C, et al. Lung cancers associated with cystic airspaces: underrecognized features of early disease. RadioGraphics. 2018;38:704–17.CrossRef
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Fintelmann FJ, Brinkmann JK, Jeck WR, et al. Lung cancers associated with cystic airspaces: natural history, pathologic correlation, and mutational analysis. J Thorac Imaging. 2017;32:176–88.CrossRef
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Oudkerk M, Devaraj A, Vliegenthart R, et al. European position statement on lung cancer screening. Lancet Oncol. 2017;18:e754–66.CrossRef
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Metadata
Title
Lung Cancer Associated with Cystic Airspaces in the Screening Perspective
Author
Mario Mascalchi, MD, PhD
Publication date
01-12-2020
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology / Issue Special Issue 3/2020
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-020-08929-1

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