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Addiction Science & Clinical Practice
Published in: Addiction Science & Clinical Practice 1/2021

Open Access 01-12-2021 | Opioids | Study Protocol

Housing, opportunities, motivation and engagement (HOME) for homeless youth at-risk for opioid use disorder: study protocol for a randomized controlled trial

Authors: Natasha Slesnick, Laura Chavez, Alicia Bunger, Ruri Famelia, Jodi Ford, Xin Feng, Sarah Higgins, Eugene Holowacz, Soren Jaderlund, Ellison Luthy, Allen Mallory, Jared Martin, Laura Walsh, Tansel Yilmazer, Kelly Kelleher

Published in: Addiction Science & Clinical Practice | Issue 1/2021

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Abstract

Background

Homeless youth experience high rates of substance use disorders, exposures to violence, mental and physical health conditions, and mortality. They have been particularly affected by the opioid crisis. However, no study to date has used a randomized controlled design to test preventive interventions of opioid and other drug use among this vulnerable population. Resolution of youth homelessness through housing and supportive services including prevention services, often referred to as “Housing First,” has great potential to reduce the likelihood for the development of an opioid use disorder as well as other problem behaviors associated with living on the streets. Housing First has been tested through randomized trials among homeless adults with mental health and substance use disorders, but has not been empirically tested for opioid prevention among homeless youth.

Methods

Homeless youth will be recruited from a drop-in shelter site frequented by disconnected youth; they will be screened for eligibility, including current homelessness, age 18–24 years, and not currently meeting criteria for opioid use disorder (OUD). In a controlled trial, 240 youth will then be randomized to one of two conditions, (1) housing + opioid and related risk prevention services, or (2) opioid and related risk prevention services alone. This project utilizes existing efficacious models of prevention to address opioid-related risks, including motivational interviewing, strengths-based outreach and advocacy, and an HIV risk preventive intervention. Follow-up will be conducted at 3, 6, 9 and 12-months post-baseline. The economic cost of each intervention will be determined to support implementation decisions with other providers and their funders.

Discussion

This study will provide essential information for researchers and providers on the efficacy of housing + opioid and related risk prevention services in an RCT for effects on opioid use and mechanisms underlying change. Because youth experiencing homelessness are at increased risk for a variety of adverse outcomes, the proposed intervention may produce substantial health care benefits to the youths and society at large.
Trial registration ClinicalTrials.gov, NCT04135703, Registered October 13, 2019, https://​clinicaltrials.​gov/​ct2/​show/​NCT04135703?​term=​NCT04135703&​draw=​2&​rank=​1#contacts
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Metadata
Title
Housing, opportunities, motivation and engagement (HOME) for homeless youth at-risk for opioid use disorder: study protocol for a randomized controlled trial
Authors
Natasha Slesnick
Laura Chavez
Alicia Bunger
Ruri Famelia
Jodi Ford
Xin Feng
Sarah Higgins
Eugene Holowacz
Soren Jaderlund
Ellison Luthy
Allen Mallory
Jared Martin
Laura Walsh
Tansel Yilmazer
Kelly Kelleher
Publication date
01-12-2021
Publisher
BioMed Central
Keywords
Opioids
Opioids
Published in
Addiction Science & Clinical Practice / Issue 1/2021
Electronic ISSN: 1940-0640
DOI
https://doi.org/10.1186/s13722-021-00237-7

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