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Systematic Reviews
Published in: Systematic Reviews 1/2019

Open Access 01-12-2019 | Malnutrition | Systematic review update

Recovery rate and determinants of severe acute malnutrition children treatment in Ethiopia: a systematic review and meta-analysis

Authors: Kassahun Gebeyehu Yazew, Chanyalew Worku Kassahun, Amare Wondim Ewnetie, Habtamu Kerebih Mekonen, Endalamaw Salilew Abagez

Published in: Systematic Reviews | Issue 1/2019

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Abstract

Background

Severe acute malnutrition affects more than 20 million children. Africa is pointed out as a region where the problem is highly prevalent. There were individual studies on the recovery rate and its determinants among children with severe acute malnutrition in Ethiopia. But, there is no national pooled estimate. Therefore, this systematic review and meta-analysis aimed to estimate the recovery rate and determinants among children with severe acute malnutrition admitted to the therapeutic feeding unit in Ethiopia.

Methods

The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline was followed in this study. Studies were accessed through electronic web-based search from PubMed, Cochrane Library, Google Scholar, and EMBASE. The statistical analysis was conducted using STATA version-11 software. The pooled prevalence was estimated with 95% confidence intervals using a random-effects model.

Result

A total of 12 studies were included with 2658 participants in the analysis. The overall pooled estimated recovery rate among children with severe acute malnutrition admitted to the inpatient therapeutic feeding unit in Ethiopia was 72.02 % (CI, 64.83, 79.22%). In the subgroup analysis, the highest estimate (80.29%) was observed in studies conducted in Oromia regional state, while 68.63% was observed in studies Southern Nation Nationality of people region 68.63%. Children who had no congestive heart failure were 4.88 times (OR, 4.88; 95% CI, 2.246, 10.586) more likely to recover than their counterparts.

Conclusion

The recovery rate among severe acute malnourished children on the therapeutic feeding unit in Ethiopia lied within the international minimum sphere. Hence, health care providers shall strengthen the management of severe acute malnutrition and management other co-morbidities like congestive heart failure.

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Appendix
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Literature
1.
Collins S, Dent N, Binns P, Bahwere P, Sadler K, Hallam A. Management of severe acute malnutrition in children. Lancet. 2006;368(9551):1992–2000.CrossRefPubMed
2.
Organization WH. World Food Program, United Nations System Standing Committee on Nutrition, United Nations Children’s Fund (2007) Community-based management of severe acute malnutrition. Geneva: World Health Organization; 2008.
3.
MoH F. National strategy for child survival in Ethiopia. Ethiopia: Addis Ababa; 2005.
4.
WHO U. Basics Nutrition Essentials: a guide for health managers. Geneva: World Health organization; 1999.
5.
Lenters LM, Wazny K, Webb P, Ahmed T, Bhutta ZA. Treatment of severe and moderate acute malnutrition in low- and middle-income settings: a systematic review, meta-analysis and Delphi process. BMC Public Health. 2013;13(3):S23.CrossRefPubMedPubMedCentral
6.
Collins S, Sadler K, Dent N, Khara T, Guerrero S, Myatt M, et al. Key issues in the success of community-based management of severe malnutrition. Food Nutr Bull. 2006;27(3_suppl3):S49–82.CrossRefPubMed
7.
8.
Grobler-Tanner C, Collins S. Community Therapeutic Care (CTC): a new approach to managing acute malnutrition in emergencies and beyond; 2004.
9.
Balaseltan EYs, Macro O. Ethiopia demographic and health survey, 2005: Central Statistical Authority; 2006.
10.
Caulfield LE, de Onis M, Blössner M, Black RE. Undernutrition as an underlying cause of child deaths associated with diarrhea, pneumonia, malaria, and measles. Am J Clin Nutr. 2004;80(1):193–8.CrossRefPubMed
11.
Esubalew D, Kiflu M, Tessema T. Community based emergency response to reduce acute malnutrition and improved access to nutritional support and care. Jarcoo consulting. 2009.
12.
Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JP, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. PLoS Med. 2009;6(7):e1000100.PubMedPubMedCentral
13.
Munn Z, Moola S, Riitano D, Lisy K. The development of a critical appraisal tool for use in systematic reviews addressing questions of prevalence. Int J Health Policy Manag. 2014;3(3):123.CrossRefPubMedPubMedCentral
14.
George BJ, Aban IB. An application of meta-analysis based on DerSimonian and Laird method. Springer; 2016.
15.
IntHout J, Ioannidis JP, Borm GF. The Hartung-Knapp-Sidik-Jonkman method for random effects meta-analysis is straightforward and considerably outperforms the standard DerSimonian-Laird method. BMC Med Res Methodol. 2014;14(1):25.CrossRefPubMedPubMedCentral
16.
Knol M, Twisk JW, Beekman AT, Heine R, Snoek FJ, Pouwer F. Depression as a risk factor for the onset of type 2 diabetes mellitus. A meta-analysis. Diabetologia. 2006;49(5):837.CrossRefPubMed
17.
Park M, Katon WJ, Wolf FM. Depression and risk of mortality in individuals with diabetes: a meta-analysis and systematic review. Gen Hosp Psychiatry. 2013;35(3):217–25.CrossRefPubMedPubMedCentral
18.
Nouwen A, Winkley K, Twisk J, Lloyd CE, Peyrot M, Ismail K, et al. Type 2 diabetes mellitus as a risk factor for the onset of depression: a systematic review and meta-analysis. Springer; 2010.
19.
Sarokhani D, Delpisheh A, Veisani Y, Sarokhani MT, Manesh RE, Sayehmiri K. Prevalence of depression among university students: a systematic review and meta-analysis study. Depress Res Treat. 2013;2013.
20.
Jarso H, Workicho A, Alemseged F. Survival status and predictors of mortality in severely malnourished children admitted to Jimma University Specialized Hospital from 2010 to 2012, Jimma, Ethiopia: a retrospective longitudinal study. BMC Pediatr. 2015;15(1):76.CrossRefPubMedPubMedCentral
21.
Mena MB, Dedefo MG, Billoro BB. Treatment outcome of severe acute malnutrition and its determinants among pediatric patients in West Ethiopia. Int J Pediatr. 2018;2018.
22.
Ashagrie Terefe Abeje TWG, Malefia YD, Befftu BB. Analysis of hospital records on treatment outcome of severe acute malnutrition: the case of Gondar University Tertiary Hospital. Pediatric therapeutics. 2016;6(2):1000283.
23.
Berti A, Bregani ER, Manenti F, Pizzi C. Outcome of severely malnourished children treated according to UNICEF 2004 guidelines: a one-year experience in a zone hospital in rural Ethiopia. Trans R Soc Trop Med Hyg. 2008;102(9):939–44.CrossRefPubMed
24.
Kabeta A, Bekele G. Factors associated with treatment outcomes of under-five children with severe acute malnutrition admitted to therapeutic feeding unit of Yirgalem Hospital. Clinics Mother Child Health. 2017;14(261):2.
25.
Misganaw C, Mesfin M, Tesfaye M, Derese A. Retrospective study on outcome of in-patient treatment of severe acute malnutrition in Jimma University specialized hospital from September 2011-September 2012. Journal of Diagnostics. 2014;1(2):18–28.CrossRef
26.
Mekuria G, Derese T, Hailu G. Treatment outcome and associated factors of severe acute malnutrition among 6–59 months old children in Debre Markos and Finote Selam hospitals, Northwest Ethiopia: a retrospective cohort study. BMC Nutrition. 2017;3(1):42.CrossRefPubMedPubMedCentral
27.
Chane T, Oljira L, Atomesa E, Agedew E. Treatment outcome and associated factors among under-five children with severe acute malnutrition admitted to therapeutic feeding unit in Woldia hospital, North Ethiopia. Nutrition & Food Sciences. 2014.
28.
Desyibelew HD, Fekadu A, Woldie H. Recovery rate and associated factors of children age 6 to 59 months admitted with severe acute malnutrition at inpatient unit of Bahir Dar Felege Hiwot Referral hospital therapeutic feeding unite, northwest Ethiopia. PLoS One. 2017;12(2):e0171020.CrossRefPubMedPubMedCentral
29.
Oumer A, Mesfin F, Demena M. Survival status and predictors of mortality among children aged 0-59 months admitted with severe acute malnutrition in dilchora referral hospital, Eastern Ethiopia. East African Journal of Health and Biomedical Sciences. 2016;1(1):13–22.
30.
Desta K. Survival status and predictors of mortality among children aged 0–59 months with severe acute malnutrition admitted to stabilization center at Sekota Hospital Waghemra Zone. J Nutr Disord Ther. 2015;5:160.
31.
Girum T, Kote M, Tariku B, Bekele H. Survival status and predictors of mortality among severely acute malnourished children< 5 years of age admitted to stabilization centers in Gedeo Zone: a retrospective cohort study. Ther Clin Risk Manag. 2017;13:101.CrossRefPubMedPubMedCentral
32.
Baker W, Michael White C, Cappelleri J, Kluger J, Coleman C. From the Health Outcomes P, et al. Understanding heterogeneity in meta-analysis: the role of meta-regression. Int J Clin Pract. 2009;63(10):1426–34.CrossRefPubMed
33.
Melsen W, Bootsma M, Rovers M, Bonten M. The effects of clinical and statistical heterogeneity on the predictive values of results from meta-analyses. Clin Microbiol Infect. 2014;20(2):123–9.CrossRefPubMed
34.
Hardy RJ, Thompson SG. Detecting and describing heterogeneity in meta-analysis. Stat Med. 1998;17(8):841–56.CrossRefPubMed
35.
36.
Layton R. The Sphere Project: Humanitarian charter and minimum standards in disaster response [book review]. Australian Journal of Emergency Management, The. 2001;16(1):37.
37.
Yvonne G. Management of severe acute malnutrition in Africa. University of Aberdeen, Department of Medicine and Therapeutics: UK. 2000;8:24-32.
38.
Mbaya D, Bitok LK, Karani AK, Osano B, Habtu M. Outcomes of severely malnourished children aged 6-59 months on outpatient management program in Kitui County Hospital, Kenya. Open Journal of Pediatrics. 2015;5(04):326.CrossRef
39.
Singh K, Badgaiyan N, Ranjan A, Dixit HO, Kaushik A, Kushwaha KP, et al. Management of children with severe acute malnutrition: experience of Nutrition Rehabilitation Centers in Uttar Pradesh, India. Indian Pediatr. 2014;51(1):21–5.CrossRefPubMed
40.
Ahmed S, Ejaz K, Mehnaz A, Adil F. Implementing WHO feeding guidelines for inpatient management of malnourished children. Journal of the College of Physicians and Surgeons--Pakistan: JCPSP. 2014;24(7):493–7.PubMed
41.
Sadler K, Puett C, Mothabbir G, Myatt M. Community case management of severe acute malnutrition in southern Bangladesh. Boston: Tufts University; 2011.
42.
Defourny I, Drouhin E, Terzian M, Taty M, Sekkenes J, Tectonidis M. Scaling up the treatment of acute childhood malnutrition in Niger. Field Exchange. 2006.
43.
Dent N. Outpatient management of acute malnutrition in a Kenyan urban slum context: caseloads and challenges. Malawi Med J. 2009;21:123–59.
44.
Dale NM, Myatt M, Prudhon C, Briend A. Using mid-upper arm circumference to end treatment of severe acute malnutrition leads to higher weight gains in the most malnourished children. PLoS One. 2013;8(2):e55404.CrossRefPubMedPubMedCentral
45.
De Maayer T, Saloojee H. Clinical outcomes of severe malnutrition in a high tuberculosis and HIV setting. Archives of disease in childhood. 2011:archdischild 205039.
Metadata
Title
Recovery rate and determinants of severe acute malnutrition children treatment in Ethiopia: a systematic review and meta-analysis
Authors
Kassahun Gebeyehu Yazew
Chanyalew Worku Kassahun
Amare Wondim Ewnetie
Habtamu Kerebih Mekonen
Endalamaw Salilew Abagez
Publication date
01-12-2019
Publisher
BioMed Central
Keyword
Malnutrition
Published in
Systematic Reviews / Issue 1/2019
Electronic ISSN: 2046-4053
DOI
https://doi.org/10.1186/s13643-019-1249-4

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