Top

EJNMMI Research

Published in:

Open Access 01-12-2019 | Magnetic Resonance Imaging | Letter to the Editor

¹⁸F-florbetapir PET/MRI for quantitatively monitoring demyelination and remyelination in acute disseminated encephalomyelitis

Authors: Min Zhang, Jun Liu, Biao Li, Sheng Chen

Published in: EJNMMI Research | Issue 1/2019

Excerpt

Dear Editor, …

Available only for authorised users

Young NP, Weinshenker BG, Lucchinetti CF. Acute disseminated encephalomyelitis: current understanding and controversies. Semin Neurol. 2008;28(1):84–94. https://doi.org/10.1055/s-2007-1019130.CrossRefPubMed

Thompson AJ, Banwell BL, Barkhof F, Carroll WM, Coetzee T, Comi G, et al. Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria. The Lancet Neurol. 2018;17(2):162–73. https://doi.org/10.1016/S1474-4422(17)30470-2.CrossRefPubMed

McCreary CR, Bjarnason TA, Skihar V, Mitchell JR, Yong VW, Dunn JF. Multiexponential T2 and magnetization transfer MRI of demyelination and remyelination in murine spinal cord. NeuroImage. 2009;45(4):1173–82. https://doi.org/10.1016/j.neuroimage.2008.12.071.CrossRefPubMedPubMedCentral

Zhang J, Kolind SH, Laule C, MacKay AL. Comparison of myelin water fraction from multiecho T2 decay curve and steady-state methods. Magn Reson Med. 2015;73(1):223–32. https://doi.org/10.1002/mrm.25125.CrossRefPubMed

Stankoff B, Freeman L, Aigrot MS, Chardain A, Dolle F, Williams A, et al. Imaging central nervous system myelin by positron emission tomography in multiple sclerosis using [methyl-(1)(1)C]-2-(4′-methylaminophenyl)- 6-hydroxybenzothiazole. Ann Neurol. 2011;69(4):673–80. https://doi.org/10.1002/ana.22320.CrossRefPubMed

Faria Dde P, Copray S, Sijbesma JW, Willemsen AT, Buchpiguel CA, Dierckx RA, et al. PET imaging of focal demyelination and remyelination in a rat model of multiple sclerosis: comparison of [11C] MeDAS, [11C] CIC and [11C]PIB. Eur J Nucl Med Mol Imaging. 2014;41(5):995–1003. https://doi.org/10.1007/s00259-013-2682-6.CrossRefPubMed

Bodini B, Veronese M, Garcia-Lorenzo D, Battaglini M, Poirion E, Chardain A, et al. Dynamic imaging of individual remyelination profiles in multiple sclerosis. Ann Neurol. 2016;79(5):726–38. https://doi.org/10.1002/ana.24620.CrossRefPubMedPubMedCentral

Goodheart AE, Tamburo E, Minhas D, Aizenstein HJ, McDade E, Snitz BE, et al. Reduced binding of Pittsburgh Compound-B in areas of white matter hyperintensities. NeuroImage Clinical. 2015;9:479–83. https://doi.org/10.1016/j.nicl.2015.09.009.CrossRefPubMedPubMedCentral

Zeydan B, Lowe VJ, Schwarz CG, Przybelski SA, Tosakulwong N, Zuk SM, et al. Pittsburgh compound-B PET white matter imaging and cognitive function in late multiple sclerosis. Mult Scler. 2018;24(6):739–49. https://doi.org/10.1177/1352458517707346.CrossRefPubMed

10.

Glodzik L, Rusinek H, Li J, Zhou C, Tsui W, Mosconi L, et al. Reduced retention of Pittsburgh compound B in white matter lesions. Eur J Nucl Med Mol Imaging. 2015;42(1):97–102. https://doi.org/10.1007/s00259-014-2897-1.CrossRefPubMed

11.

Matias-Guiu JA, Cabrera-Martin MN, Matias-Guiu J, Oreja-Guevara C, Riola-Parada C, Moreno-Ramos T, et al. Amyloid PET imaging in multiple sclerosis: an (18)F-florbetaben study. BMC Neurol. 2015;15:243. https://doi.org/10.1186/s12883-015-0502-2.CrossRefPubMedPubMedCentral

12.

Matias-Guiu JA, Cabrera-Martin MN, Cortes-Martinez A, Pytel V, Moreno-Ramos T, Oreja-Guevara C, et al. Amyloid PET in pseudotumoral multiple sclerosis. Mult Scler Relat Disord. 2017;15:15–7. https://doi.org/10.1016/j.msard.2017.05.002.CrossRefPubMed

13.

Pietroboni AM, Carandini T, Colombi A, Mercurio M, Ghezzi L, Giulietti G, et al. Amyloid PET as a marker of normal-appearing white matter early damage in multiple sclerosis: correlation with CSF beta-amyloid levels and brain volumes. Eur J Nucl Med Mol Imaging. 2019;46(2):280–7. https://doi.org/10.1007/s00259-018-4182-1.CrossRefPubMed

14.

Zhang M, Hugon G, Bouillot C, Bolbos R, Langlois JB, Billard T, et al. Evaluation of myelin radiotracers in the lysolecithin rat model of focal demyelination: beware of pitfalls! Contrast Media Mol Imaging. 2019;2019:9294586. https://doi.org/10.1155/2019/9294586.CrossRefPubMedPubMedCentral

15.

Plemel JR, Liu WQ, Yong VW. Remyelination therapies: a new direction and challenge in multiple sclerosis. Nat Rev Drug Discov. 2017;16(9):617–34. https://doi.org/10.1038/nrd.2017.115.CrossRefPubMed

Title: 18F-florbetapir PET/MRI for quantitatively monitoring demyelination and remyelination in acute disseminated encephalomyelitis
Authors: Min Zhang
Jun Liu
Biao Li
Sheng Chen
Publication date: 01-12-2019
Publisher: Springer Berlin Heidelberg
Keywords: Magnetic Resonance Imaging
Magnetic Resonance Imaging
Multiple Sclerosis
Demyelinating Disease
Positron Emission Tomography
Published in: EJNMMI Research / Issue 1/2019
Electronic ISSN: 2191-219X
DOI: https://doi.org/10.1186/s13550-019-0568-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

¹⁸F-florbetapir PET/MRI for quantitatively monitoring demyelination and remyelination in acute disseminated encephalomyelitis

Excerpt

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Excerpt

Please log in to get access to this content

Other articles of this Issue 1/2019

Phase analysis single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) detects dyssynchrony in myocardial scar and increases specificity of MPI

Reliability of visual assessment by non-expert nuclear medicine physicians and appropriateness of indications of [123I]FP-CIT SPECT imaging by neurologists in patients with early drug-naive Parkinson’s disease

Repeatability of tumor blood flow quantification with 82Rubidium PET/CT in prostate cancer — a test-retest study

Quantifying disease activity in rheumatoid arthritis with the TSPO PET ligand 18F-GE-180 and comparison with 18F-FDG and DCE-MRI

Correction to: 3D skeletal uptake of 18F sodium fluoride in PET/CT images is associated with overall survival in patients with prostate cancer

Biodistribution and radiation dosimetry of [18F]-JK-PSMA-7 as a novel prostate-specific membrane antigen-specific ligand for PET/CT imaging of prostate cancer