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Insights into Imaging
Published in: Insights into Imaging 1/2020

01-12-2020 | Ultrasound | Original Article

The value of 2D speckle-tracking strain echocardiography in evaluating the relationship between carotid elasticity and left ventricular systolic function in patients with diabetic nephropathy

Authors: Xiuyun Li, Hongju Kou, Yanyan Dong, Chao Zheng, Pengfei Wang, Maosheng Xu, Chunpeng Zou, Liang Wang

Published in: Insights into Imaging | Issue 1/2020

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Abstract

Objective

To investigate the relationship between the elasticity of the carotid artery and the LV (left ventricle) systolic function in patients with diabetic nephropathy (DN) by using two-dimensional speckle-tracking strain echocardiography (2D-STE).

Methods

DN patients (n = 108) and control subjects (n = 112), all of whom underwent echocardiography and carotid ultrasound. Analysis of LV GLS (global longitudinal strain) from the apical two-chamber (2C), three-chamber (3C), and four-chamber (4C) views. Meanwhile, the circumferential strain (CS) of the carotid artery was obtained from the view of the short-axis right common carotid artery. The differences between the two groups were compared, and a correlation analysis between CS and GLS was performed.

Results

The 4CGLS, 2CGLS, 3CGLS, and CS of the DN group were significantly lower at significant levels in contrast to the control group (p < 0.05). There was a significantly positive correlation of CS with 4CGLS, 2CGLS, and 3CGLS in all subjects (r = 0.809, p = 0.000; r = 0.830, p = 0.000; r = 0.830, p = 0.000, respectively).

Conclusion

2D-STE is a relatively new technique for assessing the mechanical characteristics of the carotid artery in patients with DN. Reduced values of CS correlate with reduced LV systolic function as evaluated by strain measurements, which can predict the risk of systolic dysfunction of LV.
Literature
1.
2.
Guariguata L, Whiting DR, Hambleton I, Beagley J, Linnenkamp U, Shaw JE (2014) Global estimates of diabetes prevalence for 2013 and projections for 2035. Diabetes Res Clin Pract 103:137–149PubMedCrossRef
3.
4.
Wang J, Wang F, Liu S, Zhou M, Zhang L, Zhao M (2017) Reduced kidney function, albuminuria, and risks for all-cause and cardiovascular mortality in China: a population-based cohort study. BMC Nephrol 18:188PubMedPubMedCentralCrossRef
5.
Chronic Kidney Disease Prognosis Consortium, Matsushita K, van der Velde M et al (2010) Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis. Lancet 375:2073–2081
6.
Sasso FC, Chiodini P, Carbonara O et al (2012) High cardiovascular risk in patients with type 2 diabetic nephropathy: the predictive role of albuminuria and glomerular filtration rate. The NID-2 Prospective Cohort Study. Nephrol Dial Transplant 27:2269–2274PubMedCrossRef
7.
Laurent S, Katsahian S, Fassot C et al (2003) Aortic stiffness is an independent predictor of fatal stroke in essential hypertension. Stroke 34:1203–1206PubMedCrossRef
8.
Chow B, Rabkin SW (2015) The relationship between arterial stiffness and heart failure with preserved ejection fraction: a systemic meta-analysis. Heart Fail Rev 20:291–303PubMedCrossRef
9.
Mancia G, De Backer G, Dominiczak A et al (2007) 2007 Guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J 28:1462–1536PubMed
10.
Groenink M, de Roos A, Mulder BJ, Spaan JA, van der Wall EE (1998) Changes in aortic distensibility and pulse wave velocity assessed with magnetic resonance imaging following beta-blocker therapy in the Marfan syndrome. Am J Cardiol 82:203–208PubMedCrossRef
11.
Mackenzie IS, Wilkinson IB, Cockcroft JR (2002) Assessment of arterial stiffness in clinical practice. QJM 95:67–74PubMedCrossRef
12.
Chan J, Shiino K, Obonyo NG et al (2017) Left ventricular global strain analysis by two-dimensional speckle-tracking echocardiography: the learning curve. J Am Soc Echocardiogr 30:1081–1090PubMedCrossRef
13.
14.
Ryczek R, Krzesinski P, Krzywicki P, Smurzynski P, Cwetsch A (2011) Two-dimensional longitudinal strain for the assessment of the left ventricular systolic function as compared with conventional echocardiographic methods in patients with acute coronary syndromes. Kardiol Pol 69:357–362PubMed
15.
Moreira HT, Nwabuo CC, Armstrong AC et al (2017) Reference ranges and regional patterns of left ventricular strain and strain rate using two-dimensional speckle-tracking echocardiography in a healthy middle-aged black and white population: the CARDIA study. J Am Soc Echocardiogr 30:647–658PubMedPubMedCentralCrossRef
16.
Collier P, Phelan D, Klein A (2017) A test in context: myocardial strain measured by speckle-tracking echocardiography. J Am Coll Cardiol 69:1043–1056PubMedCrossRef
17.
Hubbard RT, Arciniegas Calle MC, Barros-Gomes S et al (2017) 2-dimensional speckle tracking echocardiography predicts severe coronary artery disease in women with normal left ventricular function: a case-control study. BMC Cardiovasc Disord 17:231PubMedPubMedCentralCrossRef
18.
Kowalczyk E, Kasprzak JD, Wejner-Mik P, Wdowiak-Okrojek K, Lipiec P (2019) Diagnostic utility of two-dimensional speckle tracking echocardiography to identify ischemic etiology of left ventricular systolic dysfunction. Echocardiography 36:702–706PubMedCrossRef
19.
Atici A, Barman HA, Durmaz E et al (2019) Predictive value of global and territorial longitudinal strain imaging in detecting significant coronary artery disease in patients with myocardial infarction without persistent ST-segment elevation. Echocardiography 36:512–520PubMedCrossRef
20.
Al Saikhan L, Hughes AD, Chung WS, Alsharqi M, Nihoyannopoulos P (2019) Left atrial function in heart failure with mid-range ejection fraction differs from that of heart failure with preserved ejection fraction: a 2D speckle-tracking echocardiographic study. Eur Heart J Cardiovasc Imaging 20:279–290PubMedCrossRef
21.
Zou C, Jiao Y, Li X, Zheng C, Chen M, Hu C (2015) Role of ultrasonography in the evaluation of correlation between strain and elasticity of common carotid artery in patients with diabetic nephropathy. Int J Clin Exp Med 8:17765–17772PubMedPubMedCentral
22.
Oishi Y, Mizuguchi Y, Miyoshi H, Iuchi A, Nagase N, Oki T (2008) A novel approach to assess aortic stiffness related to changes in aging using a two-dimensional strain imaging. Echocardiography 25:941–945PubMedCrossRef
23.
Tervaert TW, Mooyaart AL, Amann K et al (2010) Pathologic classification of diabetic nephropathy. J Am Soc Nephrol 21:556–563CrossRef
24.
Li R, Cai J, Tegeler C, Sorlie P, Metcalf PA, Heiss G (1996) Reproducibility of extracranial carotid atherosclerotic lesions assessed by B-mode ultrasound: the Atherosclerosis Risk in Communities Study. Ultrasound Med Biol 22:791–799PubMedCrossRef
25.
Nambi V, Chambless L, He M et al (2012) Common carotid artery intima-media thickness is as good as carotid intima-media thickness of all carotid artery segments in improving prediction of coronary heart disease risk in the Atherosclerosis Risk in Communities (ARIC) study. Eur Heart J 33:183–190PubMedCrossRef
26.
Johnson HM, Turke TL, Grossklaus M et al (2011) Effects of an office-based carotid ultrasound screening intervention. J Am Soc Echocardiogr 24:738–747PubMedPubMedCentralCrossRef
27.
Polak JF, Alessi-Chinetti JM, Estes JM, Patel AR (2015) Left ventricular ejection time derived from the common carotid artery Doppler waveform: association with left ventricular ejection fraction and prediction of heart failure. J Ultrasound Med 34:1237–1242PubMedCrossRef
28.
Rhee MY, Chang HK, Kim SK (2007) Intima-media thickness and arterial stiffness of carotid artery in Korean patients with Behcet’s disease. J Korean Med Sci 22:387–392PubMedPubMedCentralCrossRef
29.
Price DJ, Wallbridge DR, Stewart MJ (2000) Tissue Doppler imaging: current and potential clinical applications. Heart 84(Suppl 2):II11–II18PubMedPubMedCentral
30.
Triantafyllou KA, Karabinos E, Kalkandi H, Kranidis AI, Babalis D (2009) Clinical implications of the echocardiographic assessment of left ventricular long axis function. Clin Res Cardiol 98:521–532PubMedCrossRef
31.
Shanks M, Thompson RB, Paterson ID et al (2013) Systolic and diastolic function assessment in fabry disease patients using speckle-tracking imaging and comparison with conventional echocardiographic measurements. J Am Soc Echocardiogr 26:1407–1414PubMedCrossRef
32.
Mizuguchi Y, Oishi Y, Miyoshi H, Iuchi A, Nagase N, Oki T (2008) The functional role of longitudinal, circumferential, and radial myocardial deformation for regulating the early impairment of left ventricular contraction and relaxation in patients with cardiovascular risk factors: a study with two-dimensional strain imaging. J Am Soc Echocardiogr 21:1138–1144PubMedCrossRef
33.
Radwan H, Hussein E (2017) Value of global longitudinal strain by two dimensional speckle tracking echocardiography in predicting coronary artery disease severity. Egypt Heart J 69:95–101PubMedCrossRef
34.
Shiino K, Yamada A, Scalia GM et al (2019) Early changes of myocardial function after transcatheter aortic valve implantation using multilayer strain speckle tracking echocardiography. Am J Cardiol 123:956–960PubMedCrossRef
35.
Vriz O, Bossone E, Bettio M, Pavan D, Carerj S, Antonini-Canterin F (2011) Carotid artery stiffness and diastolic function in subjects without known cardiovascular disease. J Am Soc Echocardiogr 24:915–921PubMedCrossRef
Metadata
Title
The value of 2D speckle-tracking strain echocardiography in evaluating the relationship between carotid elasticity and left ventricular systolic function in patients with diabetic nephropathy
Authors
Xiuyun Li
Hongju Kou
Yanyan Dong
Chao Zheng
Pengfei Wang
Maosheng Xu
Chunpeng Zou
Liang Wang
Publication date
01-12-2020
Publisher
Springer Berlin Heidelberg
Published in
Insights into Imaging / Issue 1/2020
Electronic ISSN: 1869-4101
DOI
https://doi.org/10.1186/s13244-020-00897-0

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