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Published in: Arthritis Research & Therapy 1/2018

Open Access 01-12-2018 | Research article

Functional consultation and exercises improve grip strength in osteoarthritis of the hand – a randomised controlled trial

Authors: Michaela A. Stoffer-Marx, Meike Klinger, Simone Luschin, Silvia Meriaux-Kratochvila, Monika Zettel-Tomenendal, Valerie Nell-Duxneuner, Jochen Zwerina, Ingvild Kjeken, Marion Hackl, Sylvia Öhlinger, Anthony Woolf, Kurt Redlich, Josef S. Smolen, Tanja A. Stamm

Published in: Arthritis Research & Therapy | Issue 1/2018

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Abstract

Background

Evidence for non-pharmacological interventions in hand osteoarthritis is promising but still scarce. Combined interventions are most likely to best cover the clinical needs of patients with hand osteoarthritis (OA). The aim of this study was to evaluate the effect of a combined, interdisciplinary intervention feasible in both primary and specialist care compared to routine care plus placebo in patients with hand OA.

Methods

This was a randomised, controlled 2-month trial with a blinded assessor. In the combined-intervention group, rheumatology-trained health professionals from different disciplines delivered a one-session individual intervention with detailed information on functioning, activities of daily living, physical activity, nutrition, assistive devices, instructions on pain management and exercises. Telephone follow up was performed after 4 weeks. The primary outcome was grip strength after 8 weeks. Secondary outcomes were self-reported pain, satisfaction with treatment, health status, two of the Jebsen-Taylor Hand Function subtests and the total score of the Australian/Canadian Hand Osteoarthritis Index (AUSCAN). Statistical significance was calculated by Student’s t test or the Mann-Whitney U test depending on data distribution. Binominal logistic regression models were fitted, with the primary outcome being the dependent and the group allocation being the independent variable.

Results

There were 151 participating patients (74 in the combined-intervention and 77 in the routine-care-plus-placebo group) with 2-month follow-up attendance of 84% (n = 128). Grip strength significantly increased in the combined-intervention group and decreased in the routine-care group (dominant hand, mean 0.03 bar (SD 0.11) versus − 0.03 (SD 0.13), p value = 0.001, baseline corrected values) after 8 weeks.

Conclusion

The combined one-session individual intervention significantly improved grip strength and self-reported satisfaction with treatment in patients with hand OA. It can be delivered by different rheumatology-trained health professionals and is thus also feasible in primary care.

Trial registration

ISRCTN registry, ISRCTN62513257. Registered on 17 May 2012.
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Metadata
Title
Functional consultation and exercises improve grip strength in osteoarthritis of the hand – a randomised controlled trial
Authors
Michaela A. Stoffer-Marx
Meike Klinger
Simone Luschin
Silvia Meriaux-Kratochvila
Monika Zettel-Tomenendal
Valerie Nell-Duxneuner
Jochen Zwerina
Ingvild Kjeken
Marion Hackl
Sylvia Öhlinger
Anthony Woolf
Kurt Redlich
Josef S. Smolen
Tanja A. Stamm
Publication date
01-12-2018
Publisher
BioMed Central
Published in
Arthritis Research & Therapy / Issue 1/2018
Electronic ISSN: 1478-6362
DOI
https://doi.org/10.1186/s13075-018-1747-0

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